dissertation topics on pharmacology

Pharmacology Research Paper Topics

In this page on pharmacology research paper topics , we explore the diverse and dynamic field of pharmacology and provide valuable resources for students who are tasked with writing research papers in this discipline. Pharmacology, as a branch of science, encompasses the study of how drugs interact with biological systems, aiming to understand their mechanisms of action, therapeutic uses, and potential side effects. With the growing importance of pharmacology in healthcare and drug development, it is crucial for students to delve into relevant pharmacology research paper topics that contribute to advancing knowledge and addressing current challenges in the field. Additionally, we highlight iResearchNet’s writing services, offering students the opportunity to order custom pharmacology research papers tailored to their specific needs. Our team of expert writers, equipped with in-depth knowledge of pharmacology and related fields, ensures high-quality, well-researched papers that adhere to the highest academic standards.

In the field of pharmacology, research plays a critical role in advancing our understanding of drugs, their mechanisms of action, and their impact on human health. As students of pharmacology, you may be tasked with writing research papers that explore various aspects of this dynamic discipline. To assist you in your research journey, we have curated a comprehensive list of pharmacology research paper topics that cover a wide range of subfields and emerging areas of interest. Whether you are interested in drug discovery, clinical pharmacology, pharmacogenomics, or drug safety, this list provides a wealth of ideas to inspire and guide your research endeavors.

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Drug Discovery and Development

Role of Artificial Intelligence in Drug Discovery
Personalized Medicine: Tailoring Drug Therapy to Individual Patients
Drug Repurposing: Exploring New Indications for Existing Drugs
Pharmacogenomics and Drug Response Prediction
Nanomedicine: Applications in Drug Delivery and Targeting
Innovative Approaches for Drug Formulation and Delivery
Drug Combinations: Synergistic Effects and Therapeutic Opportunities
Natural Products as Sources of Novel Therapeutic Agents
Virtual Screening and Molecular Docking in Drug Design
Pharmacokinetics and Pharmacodynamics of New Drug Entities

Clinical Pharmacology

Precision Dosing: Optimizing Drug Therapy for Individual Patients
Pharmacokinetic Variability in Special Populations (Pediatrics, Geriatrics, Pregnant Women)
Drug-Drug Interactions: Mechanisms and Clinical Implications
Adverse Drug Reactions: Identification, Prevention, and Management
Pharmacovigilance and Drug Safety Monitoring
Therapeutic Drug Monitoring: Rationale and Practical Considerations
Clinical Trials in Pharmacology: Design, Implementation, and Analysis
Drug Development and Regulatory Approval Processes
Pharmacoeconomics: Evaluating the Cost-Effectiveness of Drug Therapy
Ethical Considerations in Clinical Pharmacology Research

Neuropharmacology and Psychopharmacology

Mechanisms of Action and Therapeutic Applications of Antidepressant Drugs
Neurotransmitter Systems and Their Role in Mental Health Disorders
Psychotropic Drugs and Their Impact on Cognitive Functioning
Novel Approaches for Targeting Neurodegenerative Disorders
Pharmacological Management of Substance Use Disorders
Pharmacogenetics in Psychiatry: Implications for Individualized Treatment
Role of Neuroinflammation in Neurological and Psychiatric Disorders
Neuropharmacology of Sleep and Wakefulness
Pharmacotherapy for Schizophrenia: Current Trends and Future Directions
Novel Treatments for Anxiety and Mood Disorders

Pharmacokinetics and Drug Metabolism

Drug Transporters and Their Role in Drug Disposition
Pharmacogenetics and Personalized Drug Therapy
Pharmacokinetic Variability and Its Impact on Drug Response
Drug Metabolism Pathways and Enzyme Polymorphisms
Drug-Drug Interactions: Mechanisms and Clinical Significance
Predictive Modeling in Pharmacokinetics and Dose Optimization
Pharmacokinetics in Special Populations: Pediatrics and Geriatrics
Impact of Genetic Variation on Drug Clearance and Toxicity
Role of Pharmacokinetics in Individualizing Drug Dosage
Strategies for Improving Oral Bioavailability of Drugs

Pharmacology of Infectious Diseases

Antimicrobial Resistance: Mechanisms, Epidemiology, and Strategies
Development of Novel Antiviral Agents: Challenges and Opportunities
Pharmacotherapy for Bacterial Infections: Current Approaches and Future Directions
Antifungal Drugs: Mechanisms of Action and Resistance
Host-Pathogen Interactions and Their Implications for Drug Development
Pharmacokinetic Considerations in the Treatment of Viral Infections
Targeting Virulence Factors in Bacterial Pathogens
Drug Combination Therapy for Multidrug-Resistant Infections
Pharmacogenomics of Antimicrobial Agents
New Approaches for Antiparasitic Drug Development

Cardiovascular Pharmacology

Novel Antiplatelet Agents: Mechanisms and Clinical Applications
Antihypertensive Therapy: Current Strategies and Future Perspectives
Pharmacotherapy for Heart Failure: Advancements and Challenges
Role of Pharmacogenomics in Cardiovascular Drug Therapy
Therapeutic Potential of Antiarrhythmic Agents
Pharmacological Management of Dyslipidemia and Atherosclerosis
Emerging Therapies for Pulmonary Hypertension
Pharmacological Approaches to Preventing Thromboembolic Disorders
Cardiotoxicity of Chemotherapeutic Agents: Mechanisms and Cardioprotective Strategies
Targeting Inflammatory Pathways in Cardiovascular Disease

Pharmacology and Aging

Geriatric Pharmacotherapy: Challenges and Approaches
Age-Related Changes in Pharmacokinetics and Pharmacodynamics
Polypharmacy and Its Impact on Older Adults
Adverse Drug Reactions in the Elderly: Recognition and Prevention
Pharmacological Management of Age-Related Neurodegenerative Disorders
Geriatric Pharmacogenomics: Implications for Personalized Medicine
Drug-Related Falls and Fractures in the Elderly: Prevention and Intervention
Medication Adherence in Older Adults: Barriers and Strategies
Geriatric Pain Management: Balancing Efficacy and Safety
Optimizing Drug Therapy in Older Adults with Multiple Comorbidities

Pharmacology of Cancer

Targeted Therapies for Solid Tumors: Recent Advances and Future Directions
Immunotherapy in Cancer Treatment: Current Approaches and Challenges
Pharmacogenomics of Chemotherapy: Implications for Personalized Treatment
Drug Resistance in Cancer: Mechanisms and Strategies for Overcoming Resistance
Pharmacokinetics and Pharmacodynamics of Anticancer Agents
Combination Therapies in Oncology: Rationale and Clinical Outcomes
Oncolytic Viruses: Exploiting Viral Infections for Cancer Treatment
Cancer Stem Cells: Targeting Tumor Initiation and Progression
Development of Novel Imaging Agents for Cancer Diagnosis and Monitoring
Pharmacological Interventions for Cancer-Associated Pain Management

Pharmacology and Immunology

Immune Checkpoint Inhibitors in Cancer Immunotherapy
Autoimmune Diseases: Novel Pharmacological Approaches and Therapies
Immunomodulatory Effects of Drugs: Implications for Therapeutic Interventions
Role of Pharmacogenomics in Immunomodulatory Drug Therapy
Immunopharmacology of Allergic Reactions: Mechanisms and Treatment Strategies
Immunosuppressive Drugs in Transplantation: Balancing Efficacy and Safety
Targeting Inflammatory Pathways in Autoimmune Disorders
Immunopharmacological Interventions for Infectious Diseases
Pharmacological Modulation of Cytokines in Inflammatory Disorders
Vaccines: Advancements in Development and Delivery

Pharmacovigilance and Drug Safety

Post-Marketing Surveillance: Detecting and Evaluating Adverse Drug Reactions
Signal Detection in Pharmacovigilance: Methods and Applications
Risk Management Strategies in Drug Development and Marketing
Pharmacogenomic Biomarkers for Predicting Drug Safety
Pharmacovigilance in Special Populations: Pregnant Women and Pediatrics
Drug Safety Communication: Enhancing Patient Awareness and Education
Role of Pharmacovigilance in Drug Regulatory Affairs
Pharmacovigilance Data Mining: Leveraging Big Data for Drug Safety
Pharmacovigilance Systems and Reporting Structures
Pharmacogenetic Testing in Drug Safety Assessment

This comprehensive list of pharmacology research paper topics provides a broad range of ideas and areas to explore within the field of pharmacology. From drug discovery and development to clinical pharmacology, neuropharmacology, and pharmacokinetics, each category offers multiple topics for students to delve into and contribute to the advancement of pharmacological knowledge. Whether you are interested in the impact of pharmacogenomics on drug therapy, exploring novel treatment strategies, or investigating drug safety and pharmacovigilance, there is a wealth of research possibilities awaiting exploration. By selecting a topic of interest and following the expert advice on topic selection and research paper writing, students can embark on an enriching journey of discovery and make meaningful contributions to the field of pharmacology.

Pharmacology: Exploring the Range of Research Paper Topics

Pharmacology is a captivating and dynamic scientific discipline that focuses on the study of drugs and their effects on living organisms. It plays a crucial role in improving human health by advancing our understanding of how medications interact with biological systems. Within the field of pharmacology, there is a vast array of pharmacology research paper topics that offer students an opportunity to delve into various aspects of drug discovery, development, clinical application, and safety. In this article, we will explore the breadth and depth of pharmacology as a scientific field, highlighting the range of research paper topics it encompasses.

Drug Discovery and Development: One exciting area of pharmacology research is drug discovery and development. This field involves the identification and development of new therapeutic agents to treat a wide range of diseases. Students interested in this area can explore topics such as the exploration of novel drug targets and therapeutic approaches, investigating natural products for drug development, advancements in targeted drug delivery systems, pharmacokinetics and pharmacodynamics of new drug entities, and understanding and overcoming drug resistance mechanisms.

Clinical Pharmacology: Clinical pharmacology focuses on the application of pharmacological principles in the clinical setting. It plays a vital role in optimizing drug therapy and ensuring patient safety. Pharmacology research paper topics in this area may include pharmacogenomics, which explores the relationship between an individual’s genetic makeup and their response to medication. Other topics of interest include the identification, prevention, and management of adverse drug reactions, the design and ethical considerations in clinical trials, pharmacovigilance, and optimizing drug regimens for special populations such as pediatrics, geriatrics, and pregnant women.

Neuropharmacology and Psychopharmacology: The field of neuropharmacology examines how drugs interact with the central nervous system and influence brain function. Pharmacology research paper topics in this area may involve investigating the mechanisms of action and therapeutic applications of psychotropic drugs, exploring neurotransmitter systems and their role in neurological disorders, pharmacological interventions for Alzheimer’s disease and other neurodegenerative disorders, the psychopharmacology of substance use disorders, and the pharmacological management of mental health disorders.

Pharmacokinetics and Drug Metabolism: Pharmacokinetics and drug metabolism focus on understanding how drugs are absorbed, distributed, metabolized, and eliminated by the body. Pharmacology research paper topics in this area may include studying drug interactions, such as the mechanisms, predictions, and clinical implications of drug-drug interactions. Other topics of interest include pharmacogenetics and individual variations in drug response, the role of drug transporters in drug disposition, drug metabolism and its impact on drug-drug interactions, and the use of predictive modeling in pharmacokinetics and dosing optimization.

Pharmacology of Infectious Diseases: The pharmacology of infectious diseases involves studying how drugs can effectively treat and prevent infections. Research topics in this area may include exploring antimicrobial resistance, including its mechanisms, epidemiology, and strategies to combat it. Additionally, students may investigate the development of new antiviral agents, the pharmacological management of bacterial infections, host-pathogen interactions, and the pharmacokinetic considerations in the treatment of infectious diseases.

Cardiovascular Pharmacology: Cardiovascular pharmacology focuses on understanding the effects of drugs on the cardiovascular system. Research topics in this area may include exploring drug therapy for hypertension and current guidelines for treatment, novel anticoagulants in the prevention and treatment of thromboembolic disorders, pharmacological approaches to managing heart failure, drug-induced cardiotoxicity and strategies for prevention, and emerging pharmacotherapies for atherosclerosis and coronary artery disease.

Pharmacology and Aging: Pharmacology and aging is a specialized field that investigates how drug therapy can be optimized in older adults. Research topics in this area may include exploring geriatric pharmacotherapy, age-related changes in pharmacokinetics and pharmacodynamics, the impact of polypharmacy on older adults, the recognition and prevention of adverse drug reactions, pharmacological management of age-related neurodegenerative disorders, and strategies for improving medication adherence in the elderly.

The field of pharmacology offers a wide range of exciting research paper topics that span from drug discovery and development to clinical pharmacology, neuropharmacology, pharmacokinetics, and beyond. By exploring these topics, students can contribute to the advancement of pharmacological knowledge and make meaningful contributions to the field. Remember to choose a research topic that aligns with your interests and career aspirations, and be sure to consult with your instructors or mentors for guidance throughout your research journey. With dedication, curiosity, and a passion for improving patient care, you have the opportunity to shape the future of pharmacology research.

How to Choose a Pharmacology Research Topic

Choosing the right research paper topic is crucial for a successful academic journey in pharmacology. It allows you to explore your interests, contribute to the field, and showcase your knowledge and skills. However, with the vast scope of pharmacology, selecting a research topic can be a daunting task. In this section, we will provide you with expert advice on how to choose pharmacology research paper topics that are engaging, relevant, and have the potential for significant contribution.

Identify Your Interests : Start by identifying your areas of interest within pharmacology. Reflect on the topics that have captivated your attention during your coursework or sparked your curiosity. Consider whether you are more inclined towards drug discovery, clinical applications, pharmacokinetics, neuropharmacology, or any other subfield of pharmacology. This self-reflection will help you narrow down your options and select a topic that resonates with your passion.
Stay Updated with Current Research : To choose a compelling research topic, it is essential to stay updated with the latest advancements and trends in pharmacology. Follow reputable scientific journals, attend conferences, and engage with the pharmacological community to gain insights into the ongoing research and emerging areas of interest. This will help you identify gaps in the current knowledge and select a topic that offers the potential for novel discoveries or addressing existing challenges.
Consult with Faculty and Experts : Seek guidance from your faculty members, mentors, or experts in the field of pharmacology. They can provide valuable insights and suggest potential research areas based on their expertise and experience. Discuss your interests, goals, and research aspirations with them, and they can help you refine your research topic, provide relevant literature references, and offer valuable advice on the feasibility and scope of your chosen topic.
Consider Practicality and Resources : When selecting a research topic, consider the practicality and availability of resources. Assess whether the necessary laboratory facilities, equipment, or access to clinical data are readily accessible to conduct your research. Additionally, consider the time and resources required to complete the research within the given timeframe. Choosing a topic that aligns with the available resources will enhance the feasibility and success of your research endeavor.
Address Current Challenges or Gaps : Pharmacology is a field that constantly evolves, presenting new challenges and unanswered questions. Consider selecting a research topic that addresses current challenges or explores gaps in the existing knowledge. This could involve investigating the mechanisms of drug resistance, exploring novel drug targets, or optimizing drug regimens for specific patient populations. By tackling these challenges, you can contribute to the advancement of pharmacological science and make a meaningful impact.
Collaborate with Peers : Consider collaborating with fellow students or researchers who share similar research interests. Collaborative research projects can provide a broader perspective, foster knowledge sharing, and enhance the overall quality of your research. Collaborating with peers also allows you to divide the workload, share resources, and receive feedback and support throughout the research process.
Seek Ethical Considerations : When selecting a pharmacology research topic, it is essential to consider ethical considerations and adhere to the principles of research ethics. Ensure that your chosen topic respects patient confidentiality, follows the guidelines for the ethical use of animal subjects (if applicable), and aligns with the ethical principles outlined by regulatory bodies. Consulting with your institution’s ethics committee or research advisor can help ensure that your research project meets the required ethical standards.
Evaluate Feasibility and Novelty : Evaluate the feasibility and novelty of your chosen research topic. Consider whether the research question is answerable within the available resources and time constraints. Additionally, assess whether your topic brings something new to the field, whether it fills a knowledge gap, or offers a fresh perspective on an existing topic. A balance between feasibility and novelty is essential for a successful research paper.
Consult Literature Reviews : Conduct thorough literature reviews on your chosen topic to gain a comprehensive understanding of the existing research. Literature reviews help you identify gaps in the current knowledge and provide a foundation for your research question. They also enable you to build on previous findings, develop a robust research methodology, and position your research within the context of the broader field of pharmacology.
Remain Flexible : Lastly, remain flexible throughout the process of choosing a research topic. As you delve deeper into the literature and research process, you may discover new avenues of interest or encounter unexpected challenges. It is essential to remain open to refining or adjusting your research topic based on new insights, emerging data, or feedback from your research advisors. Flexibility allows you to adapt and ensure that your research remains relevant and impactful.

Choosing a pharmacology research paper topic is an exciting and important step in your academic journey. By following expert advice, identifying your interests, staying updated with current research, seeking guidance, considering practicality and resources, addressing current challenges or gaps, collaborating with peers, adhering to ethical considerations, evaluating feasibility and novelty, consulting literature reviews, and remaining flexible, you can select a research topic that is engaging, relevant, and has the potential to contribute to the field of pharmacology. Remember, this is your opportunity to explore, innovate, and make a lasting impact in the dynamic field of pharmacology research.

How to Write a Pharmacology Research Paper

Writing a pharmacology research paper requires careful planning, organization, and attention to detail. It is an opportunity for you to showcase your understanding of the subject matter, critical thinking skills, and ability to communicate scientific information effectively. In this section, we will provide you with expert guidance on how to write a pharmacology research paper that is well-structured, informative, and compelling.

Choose a Well-Defined Research Question : Start by formulating a clear and well-defined research question. Your research question should be focused, specific, and address a gap in the existing knowledge. Consider the significance of your research question in the context of pharmacology and how it contributes to the overall understanding of the field. A well-defined research question sets the foundation for your entire research paper.
Conduct a Thorough Literature Review : Before diving into your research, conduct a thorough literature review on the chosen topic. Familiarize yourself with the existing research, theories, and findings related to your research question. This will provide you with a solid understanding of the current state of knowledge and help you identify gaps or areas for further investigation. Additionally, the literature review will inform your research methodology and discussion of results.
Develop a Clear Structure : A well-structured research paper is essential for effectively conveying your ideas and findings. Begin with an engaging introduction that provides background information, context, and clearly states your research question. Follow with a comprehensive literature review that supports your research question and highlights the gaps in knowledge. Next, present your research methodology, including details on sample selection, data collection, and analysis methods. In the results section, present your findings in a clear and organized manner using tables, graphs, or figures as necessary. Finally, discuss your results, interpret their significance, and relate them back to your research question in the discussion section. Conclude with a concise summary of your findings and their implications.
Use Reliable and Credible Sources : Ensure that the sources you use for your research paper are reliable, credible, and peer-reviewed. Consult reputable scientific journals, textbooks, and conference proceedings. Avoid relying solely on internet sources or non-scholarly publications. Citations are critical to acknowledge the work of other researchers and to support your claims and arguments. Use a consistent citation style, such as APA, MLA, or Chicago, and follow the guidelines carefully.
Analyze and Interpret Your Data : If your research involves collecting and analyzing data, ensure that your data analysis is thorough and accurate. Use appropriate statistical methods to analyze your data and present the results in a clear and meaningful way. Interpret the findings in the context of your research question and discuss any limitations or potential sources of bias. Remember to relate your findings back to the existing literature and explain how they contribute to the broader understanding of pharmacology.
Write Clearly and Concisely : Effective scientific writing is clear, concise, and free of unnecessary jargon. Use language that is precise and straightforward, avoiding ambiguous or vague statements. Clearly articulate your ideas and ensure that your arguments are logical and well-supported by evidence. Use appropriate scientific terminology, but also consider your target audience and strive to communicate your findings in a way that is accessible to readers who may not have expertise in pharmacology.
Pay Attention to Formatting and Style : Follow the formatting and style guidelines specified by your instructor or the target journal. Pay attention to details such as font size, line spacing, margins, and headings. Use subheadings to organize your content and make it easier for readers to navigate. Adhere to the specific citation style required for your paper and ensure that your references are complete and accurate.
Revise and Edit : Revision and editing are essential steps in the writing process. Take the time to review your research paper for clarity, coherence, and accuracy. Check for grammatical errors, spelling mistakes, and punctuation errors. Ensure that your ideas flow logically and that your paper is well-structured. Consider seeking feedback from peers, instructors, or mentors to gain different perspectives and improve the overall quality of your paper.
Proofread : Before submitting your research paper, thoroughly proofread it to ensure that it is error-free. Check for any typos, inconsistencies, or formatting issues. Read your paper aloud to catch any awkward phrasing or unclear sentences. It can also be helpful to have someone else read your paper to identify any errors or areas that need improvement.
Ethical Considerations : Ensure that your research paper adheres to ethical considerations. If your research involved human subjects, ensure that you have obtained the necessary approvals and informed consent. Respect patient confidentiality and anonymity when presenting your research findings. Adhere to the ethical guidelines set by your institution or the relevant regulatory bodies.

Writing a pharmacology research paper requires careful planning, thorough research, effective communication, and attention to detail. By following the expert advice provided in this section, you can develop a well-structured and informative research paper that contributes to the field of pharmacology. Remember to choose a well-defined research question, conduct a thorough literature review, use reliable sources, analyze and interpret your data, write clearly and concisely, pay attention to formatting and style, revise and edit your paper, proofread for errors, and ensure ethical considerations are met. With diligence and commitment, your pharmacology research paper has the potential to make a meaningful impact in the field of pharmacology.

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Know the Best Pharmacology Dissertation Topics from Experts

40+ Pharmacology Dissertation Topics | Assignment Desk

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How to Choose a Pharmacology Dissertation Idea?

Excellent list of 40+ pharmacology dissertation topics, tips to write a pharmacology dissertation from experts, how can we help you with your pharmacology dissertation.

Are you asked to write a pharmacology dissertation? Well completing such a lengthy document requires accurate research, in-depth drafting, and thorough proofreading. But all this is only possible if you have a good idea to work on. So, if you are looking for pharmacology dissertation topics, then this is it! In this blog, the researchers of the Assignment Desk will offer 40+ options to choose from. But first, let us understand how to pick one topic from a long list of ideas.

Documents like dissertations are very complex and involve extensive research and analysis. Students seek dissertation help online because they cannot find a good topic for their project. So, let us learn from our experts how to choose the best idea and score decent grades on this academic task.

1. Understanding Requirements

To choose ideas for pharmacology dissertation, you should have an in-depth understanding of all the instructions and requirements provided by the professor. It is because even if you defy even the slightest rule, the dissertation can be rejected.

2. Developing Niche

The next thing to do to pick out the finest pharmacology dissertation ideas is to develop a niche. It is the main focus of your entire document, and it can be a trending issue, an unsolved problem, or a research gap.

3. Formulating Hypothesis

Every dissertation has objectives that the student wishes to accomplish using pre-defined research methods. So, before finalising the topic and dissertation titles on pharmacology, you need to formulate all your objectives and other goals.

4. Reading Literature Review

Dissertation topics on pharmacology are only useful if an ample literature review is available for reference. So, after formulating the hypothesis, browse the internet and find articles, journals, and other information relevant to the topic.

5. Considering Ethical Factors

Following ethical guidelines is very essential while writing dissertations on pharmacology. Your research should not hamper anyone's emotions, personal property, or anything else. Therefore, take into consideration rules like information consent, voluntary participation, etc.

6. Seeking Professor's Approval

Before beginning a dissertation, students need to seek the professor's approval. So, finalise your idea, and if you have any doubts, then seek assistance from experts. After this, discuss with the professor and get their approval.

Well, now that you know how to select an idea, we can move ahead. So, let us jump to the next section and unravel the list of pharmacology dissertation topics. Read each idea and pick the one that matches your requirements.

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Our researchers can provide you with a list of ideas on any subject you like. So, if you are looking for medical, psychology, or chemistry dissertation topics , then this is it! Just contact our experts, and you will get your perfect idea. Until then, dive into the list of ideas for pharmacology dissertation. So, dive ahead and pick out an amazing topic.

1. What are the current practice guidelines in pharmacology?

2. How can we make safer drugs for the treatment and care of children?

3. Discuss the future scope of clinical pharmacology in the UK.

4. What are the problems associated with integrative pharmacology? Explain in detail.

5. What are your opinions on the prevailing status of behavioural pharmacology in the UK?

6. What changes is the BPS, or British Pharmacological Society, going through?

7. Explain in detail the clinical pharmacology of anti-HIV drugs.

8. What challenges do scientists face during the development of cancer drugs?

9. Does hemodynamics have any adverse effects of oxytocin in the C-section under spinal anaesthesia?

10. What is vaccinology? State the current advancements in this area.

11. Explain the neurobiology of rapid-acting anti-depressants.

12. System pharmacology concerning metabolic bone disease.

13. What is the pharmacology of inhaled anaesthetics? Also, discuss your opinions.

14. Discuss the molecular pharmacology of rapid-acting anti-depressants.

15. What is the pharmacology of cancer, and are there any recent developments?

16. What is the apelin receptor? What are its biased agonists?

17. How can we control signalling bias, and how does the intracellular loop of the adenosine A receptor assist?

18. Explain the process of intracellular store refill.

19. Does fluoride have any effects on ion transport? Explain in detail.

20. Discuss sensory neurons and their characteristics.

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21. What is the significance of Ca signals in the chemotaxis of glioma cells?

22. Explain the novel vasoactive cardiometabolism and its uses.

23. Does anxiety affect the prothrombotic responses of the endothelium? If yes, then how?

24. Analyse the BCA as basal-like breast cancer and explain in detail.

25. What is therapeutic potential? What is the potential of intrabodies?

26. How can nig data impact healthcare and drugs?

27. What are the practice guidelines for anti-depressants in pharmacology?

28. How is the working memory of rodents affected by lamotrigine?

29. What is the prescription pattern in tertiary hospitals for antihypertensive drugs?

30. What is the treatment approach used for tuberculosis patients?

31. What processes are used in the treatment of MDR? Explain in detail.

32. What is the incremental cost of treatment for patients suffering from antimicrobial-resistant infections in the UK?

33. What intervention approach and methods are used for the treatment of generalised anxiety disorder?

34. What are somatoform disorders, and how are their patients treated? Explain the process in detail.

35. Evaluate negative drug reactions in a dermatology department.

36. What is anti-retroviral therapy, its type, and its adverse effects? Discuss in detail.

37. What are the effects and uses of cilostazol on patients suffering from peripheral arterial disease?

38. How is herpes zoster treated, and what is the common prescription pattern?

39. What is the efficacy of levocetirizine? Does it have any adverse effects?

40. Conduct an efficacy study on topical retapamulin. Also, explain its negative impacts.

41. How is a patient suffering from MDR tuberculosis treated? What methods and drugs are used?

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Recent Pharmacology Theses

Here is a list of students who have recently defended their Ph.D. Thesis in Pharmacology, along with a brief description of their thesis work.

03/10/2023 Joel Sexton - Disentangling Sequence Constraints on the Coflin N-terminal Phosphorylation Site

Mar 2023 Iris van Alderwerelt van Rosenburgh - Kinase Dynamics Underlie Mechanisms of Sensitivity and Resistance of EGFR with LUAD Mutations to Tyrosine Kinase Inhibitors

Feb 2023 Zechen Wang (Anderson Lab) - Tackling FGFR Fusion-Positive Cancers with a Novel Synergistic Combination of FGFR and HDAC Inhibitors

Mar 2022 Chun Hu - Understanding distinct roles of EGFR family mutations in different cancers

Feb 2022 Michael Bond - Towards Tumor-Cell Specific Proteolysis Targeting Chimeras: Identification of first-in-class degraders of oncogenic KRASG12C, DcpS, and MAGE-A3

Jan 2022 Joshua Sheetz - The Dead Receptor Paradox: Insights into Receptor Tyrosine Kinases with Intracellular Pseudokinase Domains

Jan 2022 Joseph Fowler - Inflammatory stress disrupts endothelial cell cholesterol homeostasis and increases SREBP2-dependent gene expression to amplify the acute inflammatory response

Aug 2021 Courtney Smith - Regulation of TIM-3 by Phosphatidylserine

Jul 2021 Brian Shi - Proteome-wide screening for mitogen-activated protein kinase docking motifs and interactors

03/02/2021 Eunice Cho - PPP6C Regulation of ERK Signaling in Melanoma

02/15/2021 Ban Edani - Structural Elucidation of the cis-prenyltransferase NgBR/DHDDS Complex Reveals Novel Insights in Regulation of Protein Glycosylation

12/14/2020 Shanique Alabi - Mutant-selective Degradation by BRAF-targeting PROTACs

11/20/2020 Valerie Su - Serine Phosphorylation of ICAP1 Inhibits its Nuclear Accumulation

11/04/2020 Vincent Duong - Evaluation of NRTI-mediated toxicity through the human mitochondrial polymerase PrimPol

08/04/2020 Victor Ruiz - Computer-Aided Discovery of New Inhibitors of C. hominis Thymidylate Synthase-Dihydrofolate Reductase

01/15/2020 Keith Weise - Regulation of activity and localization of the budding yeast kinases Kin1 and Kin2

01/10/2020 Eric Rosenberg - Perturbing the activities of chemokine receptors CXCR4 and CXCR5

11/25/2019 Yasmin Kadry - Biochemical and functional characterization of kindlin interactions

09/23/2019 Ashley Sizer - O-GlcNAc transferase-dependent regulation of serum response factor and vascular smooth muscle cell phenotype

03/01/2019 Zachary Gannam - Exploring the allosteric inhibition of a MAPK phosphatase linked to Duchenne muscular dystrophy

01/24/19 William Gray - Nucleoid Size Scaling and Intracellular Organization of Translation Across Bacteria.

01/14/19 Lee Ying - Epigentic Approaches to Understanding Adipogenesis, and Translational Approaches to Treating Obesity.

10/05/18 Molly Ryan - Understanding the Consequences of Oncogenic FGFR Mutations on Drug Resistance, Signaling, and Tumorigenesis

09/27/18 Daniel Iwamoto - Structural basis of the filamin A actin-binding domain interaction with F-actin

09/12/18 Lie Ma - Elucidation of the Activated State of Fibroblast Growth Factor Receptor

09/10/18 David E. Puleo -Targeting the Mutant JAK2 V617F Tyrosine Kinase by Small Molecules that Bind to its Pseudokinase Domain

03/01/18 Tomoaki Sasaki - Characterization of APOBEC3 Family Proteins as Potent DNA Mutators in Human Cancers

02/12/18 Elizabeth Mo - Augmentors are in vivo ligands to the ALK family of receptor tyrosine kinases: function and evolution

09/26/17 Chad Miller - Comprehensive Profiling of a Kinase Family Defines Features Essential for Selective Substrate Targeting

11/30/2016 Amelia Luciano - The Role of Akt1 & Clock S845 phosphorylation in Circadian Regulated Transcriptional Rhythms

09/23/2016 Allison Goldberg - An Exosite Required for Efficient Targeting of MAP Kinase Kinases by the Metalloproteinase Antrax Lethal Factor

08/12/2016 Yagmur Muftuoglu - Mechanisms of substrate specificity and insights into activation of phosphatidylionositol phosphate kinases

06/02/2016 Andrea Mislak - Insights into the Activity, Resistance, and Toxicity of Antivirals Targeting HIV Reverse Transcriptase

02/23/16 Phillip Murray - Discovery and Characterization of Ligands for the Receptor Tyrosine Kinase ALK: AUG-alpha, AUG-beta and Heparin

12/10/15 Yifei Yang - Molecular basis for Polycystin- 2 channel regulation and assembly its C-terminal tail

12/08/15 Jacqueline Heiss - Prion Protein Regulates Amyloid- Beta Dendritic Spine Pathology in a Mouse model if Alzheimer's Disease

10/15/15 Celeste Greer - Histone Deacetylases Positively Regulate Transcriptional Elongation

2/24/15 Oriana Fisher - Structural studies of Cerebral Cavernous Malformations 2 (CCM2) reveal the basis for its interactions with protein binding

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Home » Blog » Dissertation » Topics » Clinics » 80 Clinical Pharmacology Research Topics

80 Clinical Pharmacology Research Topics

FacebookXEmailWhatsAppRedditPinterestLinkedInIf you are an academic eager to explore captivating research topics in the domain of Clinical Pharmacology, you’re in the right spot, the quest for intriguing and impactful research topics is an essential endeavor. Whether you’re embarking on an undergraduate, master’s, or doctoral-level thesis or dissertation, selecting the right research topics can set the tone […]

If you are an academic eager to explore captivating research topics in the domain of Clinical Pharmacology, you’re in the right spot, the quest for intriguing and impactful research topics is an essential endeavor. Whether you’re embarking on an undergraduate, master’s, or doctoral-level thesis or dissertation, selecting the right research topics can set the tone for a fruitful and intellectually stimulating academic journey. Clinical Pharmacology, at its core, is a multidisciplinary field that delves into the effects of drugs and medicines on living organisms, the selection of your research topics will significantly influence the depth and breadth of knowledge you acquire and contribute to the advancement of this vital discipline.

Clinical Pharmacology, also known as pharmacological research, medicine interactions, and therapeutic drug studies, at its essence, is the scientific exploration of how drugs and medications interact with the human body, influencing their efficacy and safety profiles. It involves investigating the pharmacokinetics, pharmacodynamics, and therapeutic effects of drugs to optimize their use and improve patient outcomes.

A List Of Potential Research Topics In Clinical Pharmacology:

Analyzing the pharmacokinetics and pharmacodynamics of antiviral drugs in patients with herpes simplex virus infections.
Assessing the effects of drug-drug interactions on the pharmacokinetics and pharmacodynamics of antiepileptic drugs in pediatric epilepsy patients.
Understanding the role of pharmacogenomics in predicting response to biologic therapies for rheumatoid arthritis.
Assessing the role of personalized drug dosing strategies in optimizing chemotherapy outcomes for pediatric cancer patients.
Exploring the use of pharmacogenomic data to optimize dosing and minimize adverse effects of chemotherapy.
Analyzing the pharmacokinetics and pharmacodynamics of anticoagulant drugs in patients with venous thromboembolism.
Assessing the potential of drug-loaded liposomes in improving drug delivery to arthritic joints for rheumatoid arthritis treatment.
Assessing the pharmacological interactions and effects of herbal supplements on conventional drug therapy in chronic disease management.
Assessing the potential of nanomedicine in improving drug delivery to the central nervous system for the treatment of neurological disorders.
Examining the effects of drug-induced ocular toxicity on visual function and its implications for drug safety assessment.
Analyzing the impact of polypharmacy on adverse drug reactions and patient safety in clinical practice.
Assessing the role of clinical pharmacology in addressing antimicrobial resistance in the UK.
Evaluating the implementation and outcomes of medication reconciliation processes in UK healthcare settings.
Analyzing the pharmacokinetics and pharmacodynamics of immune checkpoint inhibitors in cancer therapy.
Investigating the potential drug-drug interactions in COVID-19 patients receiving multiple medications.
Investigating the effectiveness of medication therapy management programs in optimizing drug use in the UK.
Exploring the synergies of clinical pharmacology in addressing climate policy challenges and sustainable healthcare solutions.
Assessing the efficacy and safety of repurposed drugs for COVID-19 treatment in the UK population.
Exploring the implications of digital health technologies on medication adherence and patient outcomes in the UK.
Assessing the role of gut microbiota in drug metabolism and personalized medicine.
Analyzing the pharmacogenetic basis of individual responses to antipsychotic medications in patients with schizophrenia.
Evaluating the role of drug metabolism and transporter polymorphisms in the variability of statin response and lipid-lowering effects.
Analyzing the disparities in drug utilization and access among different socioeconomic groups in the UK.
Investigating the pharmacological interventions to mitigate the opioid epidemic and improve pain management.
Understanding the pharmacological mechanisms of drug-induced QT prolongation and its implications for drug safety assessment and monitoring.
Investigating the pharmacological mechanisms of drug-induced nephrotoxicity and its implications for drug development and clinical use.
Examining the advancements and challenges in orphan drug development and accessibility in clinical pharmacology.
Understanding the role of pharmacogenetic variations in response to antiretroviral therapy in HIV-infected individuals.
Understanding the pharmacological mechanisms and therapeutic potential of targeting neuroinflammation in neurodegenerative diseases.
Examining the effects of drug-induced kidney injury on drug clearance and dosing in critically ill patients.
Analyzing the pharmacokinetics and pharmacodynamics of antifungal drugs in critically ill patients with invasive fungal infections.
Understanding the role of pharmacogenetic variations in response to antiviral therapy in hepatitis B patients.
Evaluating the potential of personalized dosing regimens in optimizing anticoagulant therapy for atrial fibrillation patients.
Studying the impact of COVID-19 on medication adherence and patient outcomes in clinical settings.
Investigating the impact of Brexit on pharmaceutical regulations and drug accessibility in the UK.
Evaluating the potential of nano-based drug delivery systems to enhance the bioavailability and therapeutic efficacy of poorly soluble drugs.
Assessing the integration of pharmacogenomics into routine clinical practice for personalized medicine in the UK.
Investigating the role of clinical pharmacists in optimizing COVID-19 medication regimens and outcomes.
Examining the effects of drug-induced hematological toxicity on blood cell counts and clotting parameters.
Evaluating the pharmacological management of COVID-19 in elderly patients and its impact on geriatric care.
Analyzing the pharmacokinetics and pharmacodynamics of antibiotics in critically ill patients with sepsis.
Evaluating the effects of drug-induced musculoskeletal toxicity on bone density and muscle strength.
Examining the effects of drug-induced cardiotoxicity on cardiac function and its implications for clinical management.
Analyzing the impact of environmental factors on drug metabolism and pharmacological outcomes.
Understanding the role of pharmacogenetic variations in response to antifibrotic therapy in idiopathic pulmonary fibrosis patients.
Assessing the effects of drug interactions on the efficacy and safety of direct-acting antiviral agents in hepatitis C treatment.
Assessing the potential of drug-loaded microparticles in enhancing pulmonary drug delivery for respiratory diseases.
Understanding the pharmacological basis of drug-induced liver injury and its implications for drug development and clinical practice.
Examining the effectiveness of antiviral therapies in managing post-COVID complications.
Investigating the pharmacological mechanisms of drug-induced endocrine disruption and its implications for drug development and clinical use.
Examining the effectiveness of therapeutic drug monitoring in optimizing dosing regimens for immunosuppressive agents in organ transplant recipients.
Examining the effects of drug-induced dermatologic toxicity on skin barrier function and its implications for drug safety assessment.
Assessing the potential of drug-loaded hydrogels in enhancing localized drug delivery for osteoarthritis management.
Examining the effects of drug-induced respiratory toxicity on lung function and its implications for drug safety assessment.
Studying the potential therapeutic effects and safety of medical cannabis in managing chronic conditions.
Investigating the pharmacological basis of drug-induced hematological toxicity and its implications for drug development and clinical use.
Evaluating the pharmacokinetics and pharmacodynamics of biologic drugs in various disease states.
Assessing the potential of drug-loaded nanoparticles in enhancing drug delivery to solid tumors for cancer therapy.
Investigating the role of machine learning and artificial intelligence in drug discovery and development.
Understanding the role of pharmacogenetic variations in response to antipsoriatic drugs in psoriasis patients.
Integrating clinical pharmacology and advanced clinical nutrition for optimized therapeutic outcomes and patient well-being.
Studying the role of real-world evidence in drug development and post-marketing surveillance in the UK.
Investigating the pharmacological basis of drug-induced pulmonary toxicity and its implications for drug safety assessment.
Evaluating the effects of drug-induced metabolic toxicity on metabolic pathways and energy metabolism.
Evaluating the long-term cardiovascular effects of COVID-19 treatments in a clinical setting.
Evaluating the effects of drug-induced ototoxicity on hearing function and its implications for drug safety assessment.
Evaluating the potential of novel drug delivery systems for enhancing antipsychotic medication efficacy in schizophrenia patients.
Assessing the role of pharmacogenetic variations in response to antiplatelet therapy and its impact on cardiovascular outcomes in post-stent patients.
Evaluating the potential of drug repurposing in oncology for enhancing treatment options and improving patient outcomes.
Examining the effects of drug-induced liver injury on drug metabolism and disposition in human hepatocytes.
Investigating the pharmacological mechanisms of drug-induced genotoxicity and its implications for drug development and clinical use.
Investigating the pharmacokinetics and pharmacodynamics of biologic drugs for the treatment of inflammatory bowel disease.
Examining the effects of drug-induced reproductive toxicity on fertility and reproductive organs.
Understanding the role of pharmacogenetic variations in response to anti-malarial drugs in malaria patients.
Exploring the mental health implications of COVID-19 and its influence on medication adherence and efficacy.
Analyzing the pharmacokinetics and pharmacodynamics of immunosuppressive agents in transplant recipients with autoimmunity.
Investigating the impact of drug-induced QT prolongation on patient outcomes and its implications for drug development and clinical use.
Assessing the impact of COVID-19 on drug metabolism and pharmacokinetics in the UK population.
Investigating the potential of pharmacogenomic-guided opioid therapy in optimizing pain management and reducing opioid-related adverse effects.
Analyzing the effects of pharmacogenomic-guided antidepressant therapy on treatment response and remission rates in individuals with major depressive disorder.

In conclusion, Clinical Pharmacology opens the door to a rich realm of research possibilities across different academic levels. For undergraduates, delving into topics like drug metabolism pathways or medication adherence among specific patient populations can foster a foundational understanding of drug actions. Masters students can explore areas such as personalized medicine, drug-drug interactions, or novel drug delivery systems. On a doctoral level, the research scope expands further, allowing for in-depth investigation into topics like pharmacogenomics, clinical trial design, or pharmacoeconomics. Selecting a research topic aligned with your academic level and interests will not only enrich your understanding of Clinical Pharmacology but also contribute to the continuous advancement of this vital field.

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How To Choose The Best Dissertation Topic For Pharmacology And Pharmacy

Choosing a dissertation topic is an important process for the success of any research project. This is particularly true in pharmacology and pharmacy, which are two disciplines that involve complex scientific concepts and potentially impactful research outcomes.

In this article, an online tutor will provide guidance on how to choose the best dissertation topic for pharmacology and pharmacy. By following the advice offered by this tutorial, students can ensure that their chosen topic meets all requirements and provides them with the opportunity to contribute meaningfully to the field.

This article will begin by highlighting some of the key considerations when choosing a topic for one’s dissertation. It will then outline several effective approaches for narrowing down potential topics and locating relevant resources that may be useful during the research process. Finally, it will provide suggestions on how to refine one’s chosen topic and begin working towards its completion.

With these tips in mind, readers can gain a greater understanding of how to choose a suitable dissertation topic in pharmacology and pharmacy.

What Is A Dissertation Topic?

A dissertation topic is a research question or problem that guides the development of an extended academic paper.

When choosing a dissertation topic for pharmacology and pharmacy, it is important to consider the researching methods, experimental designs, ethical implications, data analysis, and literature reviews that will be required to answer the research question.

It is also important to choose a topic that is manageable within the scope of the project being undertaken.

The chosen dissertation topic should be interesting enough to keep you motivated as you progress through your research.

Additionally, make sure that there is sufficient scholarly material available on your chosen topic so that you can complete a thorough investigation of the subject matter.

Considerations For Selecting A Dissertation Topic

When it comes to choosing a dissertation topic for pharmacology and pharmacy, it is important to carefully consider a number of factors. Here are some tips to help you get started:

Brainstorming techniques: Take the time to come up with as many ideas as possible. This can involve talking to experts in the field, conducting research, and drawing inspiration from current literature.

Literature review methods: Read up on related topics to get an understanding of what has been studied before, and use this information as a starting point for your own research.

Data analysis approaches: Think about the best way to analyze data. Will you be using statistical analysis? What software will you need?

Research objectives formulation: Once you have an idea of what you would like to study, outline the specific objectives that you want to achieve with your research.

Ethical considerations: Make sure that ethical guidelines are followed throughout the process. This includes obtaining informed consent when needed and adhering to relevant regulations.

It is also important to ensure that the topic is feasible within the given timeline and resources available.

Taking all these aspects into consideration will help make sure that your dissertation project is successful.

Identifying Areas Of Interest In Pharmacology And Pharmacy

Exploring research opportunities in the field of pharmacology and pharmacy can help identify potential areas of exploration and specialization. Examining the current topics of interest in the field can help narrow down the focus of a dissertation topic that could be relevant to the field.

Exploring Research Opportunities

Exploring research opportunities in pharmacology and pharmacy can be a great way to identify areas of interest.

There are many career paths available that involve researching in the fields of pharmacology and pharmacy, and it is important to assess potential risks when considering these options.

It is also important to stay up to date on current developments within the fields so that you can make informed decisions about research opportunities.

This involves staying abreast of new research projects, industry trends, and changes in regulations or technology that may affect your work.

Doing this will help you determine which topics are best suited for your own research interests and skillset.

Ultimately, understanding the landscape of pharmacology and pharmacy is an essential part of choosing the right dissertation topic for you.

Examining Current Topics

When exploring research opportunities in pharmacology and pharmacy, it is important to consider current topics of interest.

Examining the various medical terminologies, drug interactions, and legal implications associated with a particular topic can help to determine if the research will be beneficial to those involved.

It is also essential to stay up-to-date on the latest developments within these fields so that you can make informed decisions and ensure that your research aligns with industry trends.

Ultimately, researching current topics before committing to a dissertation or any other form of research will help you identify whether this field is right for you.

Researching A Topic

In order to choose the best dissertation topic for pharmacology and pharmacy, it is important to first define a research question that is relevant to the topic. Gathering evidence to support the research question is also essential for formulating a successful dissertation.

Defining A Research Question

It is essential for pharmacologists and pharmacists to define a research question before beginning their dissertation.

Investigating literature, identifying trends, and formulating hypotheses are all key steps in this process.

It is important to ensure that the question being asked has not been addressed previously or is not too broad to be adequately addressed in a dissertation.

Gathering as much information as possible on the topic of interest and making sure that it is relevant will provide valuable insight into the scope of the project.

Additionally, conducting an exhaustive literature review of related topics can help refine the research question by identifying potential gaps or areas needing further examination.

Ultimately, defining a research question properly will set the foundation for an effective dissertation.

Gathering Evidence

Once a research question has been defined, it is time to gather evidence to help answer the question.

This can be done through a variety of methods, such as collecting empirical data, conducting a literature review, or observing clinical trials.

All of these methods provide valuable insights into the topic and help to build a strong foundation for the dissertation.

Additionally, it is important to critically evaluate any sources used to ensure accuracy and relevance in order to make sure that only reliable information is included in the dissertation.

By taking the time to properly research and gather evidence from both primary and secondary sources, one can ensure that their dissertation is well supported by facts and evidence.

Analyzing Resources

When choosing the best dissertation topic for pharmacology and pharmacy, it is important to thoroughly analyze available resources.

Engaging experts in the field of pharmacology or pharmacy can provide key insights into current topics of interest.

Moreover, exploring methodologies used by other researchers can help you gain an understanding of what approaches may be most effective in your research.

Additionally, evaluating data from previous studies can help identify potential gaps that may need to be addressed in your research.

Finally, surveying literature related to a particular topic can assist you in forming a hypothesis or developing an argument that will inform your work.

By comparing results from various sources, you can build a strong foundation for your dissertation topic.

Ultimately, carefully assessing all available resources is essential when selecting the best dissertation topic for pharmacology and pharmacy.

Developing A Research Question

When it comes to selecting a dissertation topic, it is important to prioritize your goals and identify the methods you will use.

Start by analyzing data related to pharmacology and pharmacy, research current trends in the field, and consider the implications of your findings.

It can be helpful to brainstorm ideas with your peers or professors who may have experience in your chosen field.

Additionally, some universities offer resources such as workshops or writing groups that could provide valuable insight into selecting a dissertation topic.

Ultimately, take time to carefully consider all of your options before deciding on a specific topic for your dissertation.

Writing A Research Proposal

When writing a research proposal, it is important to consider all elements of the project.

Analysis of data, data collection and methodology selection are crucial steps in the process.

Conducting a thorough literature review will ensure that your research topic is relevant and up-to-date.

Additionally, research ethics must be taken into account when selecting a topic and conducting the study.

All of these steps must be completed in order to ensure that your dissertation meets the highest standards of quality and integrity.

Therefore, it is essential to create an extensive plan for research before beginning any project.

This will ensure that all aspects of the project are properly considered, allowing you to develop an effective and comprehensive dissertation topic for pharmacology and pharmacy.

Seeking Advice From Advisors

It is important to check that your advisor has expertise and experience in the subject of pharmacology and pharmacy before seeking advice. Asking for topic ideas from your advisor is a good way to narrow down your dissertation topic and get an idea of what research you may be able to conduct.

Checking Advisor’s Expertise

When searching for advice from advisors, it is important to evaluate the expertise of the advisor. A good way to do this is by formulating objectives, conducting surveys, and analyzing data. This will provide a comprehensive overview of the advisor’s knowledge and experience in the field of pharmacology and pharmacy.

Furthermore, it will allow you to make an informed decision about whether or not they are qualified to provide guidance on selecting a dissertation topic. Additionally, don’t forget to check with other reliable sources such as professional associations or online forums for additional opinions on the advisor’s qualifications.

Ultimately, it is essential that you choose an advisor who has relevant expertise and experience necessary to help you select the best dissertation topic for pharmacology and pharmacy.

Asking For Topic Ideas

Once a suitable advisor has been identified, it is important to have an open dialogue about potential dissertation topics.

Asking for topic ideas related to pharmacology and pharmacy can help narrow down the possible topics.

For example, potential topics could include drugs and society, pharmaceutical regulation, or drug development.

Moreover, these are just some of the many areas that can be explored when selecting a dissertation topic for pharmacology and pharmacy.

It is thus essential to discuss any ideas with the advisor so that they can provide guidance and feedback on which direction to take.

This will ensure that the chosen dissertation topic is suitable for both the student’s research goals and interests as well as their academic field of study.

Obtaining Institutional Approval

Gathering Necessary Documentation is an important first step when obtaining institutional approval for your dissertation topic in pharmacology and pharmacy. It is necessary to ensure that you have all the relevant and necessary paperwork in order to move forward with the approval process.

Seeking IRB Approval is another important step when obtaining institutional approval for your dissertation topic in pharmacology and pharmacy. It is imperative to make sure that you go through all the necessary steps to ensure that your research is approved and that it follows all the ethical guidelines.

Gathering Necessary Documentation

When seeking approval for a dissertation topic in the field of pharmacology and pharmacy, it is important to gather the necessary documents that will be needed for review.

It is essential to explore all resources available and assess the data provided in order to formulate questions related to the dissertation topic.

When exploring potential resources, it is critical to contact faculty members who can provide insight into the type of research required.

Additionally, students should seek out any relevant policies or procedures associated with their institution’s approval process.

By taking these steps in advance, students can ensure they have all of the documentation they need when submitting their proposal for approval.

Seeking Irb Approval

Once the initial steps of institutional approval are complete, the next step for a student seeking to undertake a research project or dissertation in the field of pharmacology and pharmacy is to seek out IRB (Institutional Review Board) approval.

It is essential for students to ensure that all ethical standards are met when conducting any research involving human subjects. This involves identifying the study population and obtaining consent from participants.

Furthermore, it may be necessary to obtain funding from external sources, such as government grants and pharmaceutical companies.

As an online tutor, it is important to guide students through this process so they can confidently move forward with their research projects while ensuring that all ethical considerations have been taken into account.

Finalizing A Dissertation Topic

Now that you have obtained the necessary institutional approval, it is time to finalize your dissertation topic.

Brainstorming techniques can be a great way to come up with ideas for a research project. You may also consider looking at recent literature reviews in the field of pharmacology and pharmacy to see what topics have already been covered and how you could build on past findings.

Once you have brainstormed some ideas and identified areas of interest, you should start formulating hypotheses for your research. After that, you will need to decide on data collection methods and data analysis techniques that will be used to test your hypotheses.

By using these steps, you can arrive at an engaged and relevant dissertation topic in pharmacology or pharmacy that has potential to make valuable contributions to the field.

Frequently Asked Questions

What are the best practices for conducting research for a dissertation topic in pharmacology and pharmacy.

When conducting research for a dissertation topic in pharmacology and pharmacy, the best practices involve analyzing data, exploring literature, selecting resources, researching methods, and formulating hypotheses.

In order to ensure that you have the most reliable information available, it is important to review the literature carefully. Additionally, you should select a variety of resources that are relevant to your topic and analyze data stemming from those sources. It is also important to consider any potential biases when evaluating data.

Once you have gathered sufficient evidence and analyzed it carefully, you can begin to formulate a hypothesis which can be tested through further research. By following these best practices when conducting research for a dissertation topic in pharmacology and pharmacy, students will be able to form an informed opinion on their chosen subject matter.

What Is The Timeline For Completing A Dissertation In Pharmacology And Pharmacy?

Completing a dissertation in pharmacology and pharmacy requires data-driven decisions, critical thinking, analytical skills, ethical considerations, and problem solving.

Developing a timeline for completing the dissertation is essential for successful completion. It is important to develop realistic goals and timelines that are based on the scope of the project which will ensure progress is made in a timely manner.

Setting milestones along the way can help keep you on track while allowing you to adjust your timeline if needed. As an online tutor, I can provide support and guidance throughout this process to set you up for success.

What Are The Common Pitfalls To Avoid When Selecting A Dissertation Topic In Pharmacology And Pharmacy?

Selecting a dissertation topic in pharmacology and pharmacy can be a daunting task. It is important to apply criteria to the topic selection process and ensure that there is sufficient research background, literature review, and data collection available for the chosen topic.

Common pitfalls to avoid include selecting overly broad topics or topics with too narrow of a scope. Additionally, selecting overly complicated topics may lead to difficulty in collecting data or understanding the research findings.

Choosing a well thought-out dissertation topic is an essential step for writing a successful dissertation in pharmacology and pharmacy.

How Do I Know When I Have Gathered Enough Research For My Dissertation Topic In Pharmacology And Pharmacy?

When selecting a dissertation topic in pharmacology and pharmacy, it is important to ensure that the research has been sufficiently gathered.

This can involve finding resources, data analysis, time management, research ethics and conducting a literature review.

Once these steps have been completed and discussed with an academic supervisor, it should be possible to ascertain whether enough research has been conducted for the dissertation topic.

Furthermore, an online tutor can provide guidance on how to approach this process and offer practical advice on how best to move forward.

How Do I Go About Finding A Faculty Member To Serve As My Advisor For My Dissertation Project In Pharmacology And Pharmacy?

Choosing a faculty member to serve as your advisor for your dissertation project in pharmacology and pharmacy can be a daunting task.

It is important to find an advisor who is familiar with your research topic and the expectations of the publication process, who can provide guidance on data analysis, literature reviews and other research resources.

This person should also have the ability to help you navigate the publication process, as well as offer constructive feedback throughout your project.

Making sure that you choose someone who meets these criteria will help ensure that you have a successful dissertation experience.

When it comes to choosing a dissertation topic in pharmacology and pharmacy, there are a few best practices to consider.

It is important to begin the process early and develop a timeline for completion.

Additionally, it is essential to research the topic thoroughly and ensure that enough background material has been gathered for the project.

Finally, students should seek out faculty members who can provide guidance and serve as advisors throughout their dissertation project.

With careful consideration of these points, students can be well on their way to selecting an appropriate dissertation topic in pharmacology and pharmacy.

The selection of an appropriate dissertation topic is a crucial step in the successful completion of a graduate degree in pharmacology and pharmacy.

By following best practices such as early planning, thorough research, and faculty advisement, students can make sure they choose the most suitable project for their academic pursuits.

Doing so will not only help them achieve their desired end goal but also demonstrate their knowledge and abilities within their chosen field of study.

Ultimately, with thoughtful consideration of these key elements when selecting a dissertation topic in pharmacology and pharmacy, students can position themselves for success when it comes time to complete their project.

With the right approach and support from advisors, they will be able to complete their degree with confidence and pride knowing that they have achieved something remarkable.

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Clinical Pharmacology: Current Topics and Case Studies

© 2010
Markus Müller (Professor and Head of Department) 0

Department of Clinical Pharmacology, Medical University Vienna, Vienna General Hospital (AKH), Vienna, Austria

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Comprehensive overview of current topics in clinical pharmacology

Case studies for every issue

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Table of contents (26 chapters)

Front matter, introduction, the discipline of clinical pharmacology.

Markus Müller

Current issues in drug development

Current issues in drug regulation.

Marcus Müllner, Hans-Georg Eichler

Current issues in drug reimbursement

Anna Bucsics

Clinical Trials

Ethics in clinical research.

Ernst Singer, Christiane Druml

Good Clinical Practice (GCP) and scientific misconduct

Brigitte Bloechl-Daum, Christiane Druml

Phase-I studies and first-in-human trials

Ulla Derhaschnig, Bernd Jilma

Clinical trials - interventional studies

Michael Wolzt, Stefan Aschauer

Observational studies

Harald Herkner, Christoph Male

Pharmacokinetics I: PK-PD approaches - antibiotic drug development

Sreedharan N. Sabarinath, Rajendra Pratap Singh, Hartmut Derendorf

Pharmacokinetics II: 14C-labelled microdosing in assessing drug pharmacokinetics at Phase-0

Graham Lappin

Epidemiology and bio statistics

Gerhard Garhöfer, Leopold Schmetterer

Placebo effects and placebo control in clinical trials

Magdalena Pilz, Johannes Pleiner

Tools in Clinical Pharmacology

Tools in clinical pharmacology - imaging techniques.

Martin Bauer, Oliver Langer

Current concepts of pharmacogenetics, pharmacogenomics, and the “druggable” genome

Wolfgang M. Schmidt
Volker Wacheck
clinical research
clinical trial
drug development
drug research
gene therapy
pharmacodynamics
pharmacokinetics
pharmacology

About this book

Editors and affiliations, about the editor, bibliographic information.

Book Title : Clinical Pharmacology: Current Topics and Case Studies

Editors : Markus Müller

DOI : https://doi.org/10.1007/978-3-7091-0144-5

Publisher : Springer Vienna

eBook Packages : Biomedical and Life Sciences , Biomedical and Life Sciences (R0)

eBook ISBN : 978-3-7091-0144-5 Published: 04 February 2011

Edition Number : 1

Number of Pages : XXIV, 430

Topics : Pharmacology/Toxicology , Pharmacy

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Recent research project titles in Part II Pharmacology

The department offers a wide range of research projects, which are undertaken during the Lent Term. Below are a selection of projects offered recently. The subheadings are fairly arbitrary – many projects have clear impact in a range of areas – but hopefully convey the breadth of research topics available.

Understanding receptors

The role of intracellular loop 1 of the adenosine A2a receptor in mediating signalling bias
Biased agonists of the Apelin receptor
RAMP-directed signalling bias of the calcitonin-receptor-like receptor
Visualizing activation-induced structural changes in ionotropic glutamate receptors using AFM imaging

Intracellular signalling

Repurposing known drugs as inhibitors of the store-operated calcium entry pathway
How do intracellular Ca 2+ stores refill?
Calcium responses underlying Insulin-like peptide 5 signalling in mouse colonic epithelium
Effects of fluoride on ion transport in epithelial cell monolayers

Neuropharmacology

Characterisation of sensory neurones using retrograde tracing
Role of Ca 2+ signals in chemotaxis of glioma cells

Cardiovascular pharmacology

The effect of shear stress on the prothrombotic responses of the endothelium
Cl - -sensing properties of WNK4 modulates K + homeostasis in the distal nephron
‘Surfing the PHOME ’: extending and probing the druggable platelet proteome
Elucidating the mechanisms underlying neutrophil recruitment to the vascular endothelium
Novel vasoactive peptides and cardio-metabolic function

Cancer pharmacology

Novel approaches for the inhibition and degradation of intracellular protein targets associated with pancreatic and colorectal cancers
Investigating the biology of BCL11A in basal-like breast cancer
Searching for modifiers of Aurora kinase stability using tandem fluorescent protein tags

Antibacterial pharmacology

Evaluating the intrinsic mammalian toxicity of some molecules that inhibit lipoteichoic acid synthase of Gram-positive bacteria
Transport mechanism of a multidrug transporter from Vibrio cholera

Recent pharmacology dissertation titles offered in Part II BBS

The department offers a wide range of dissertation titles for students taking Part II BBS. Below are a selection of titles offered recently. The subheadings are somewhat arbitrary, but hopefully convey the wide scope of themes on offer and the huge importance of pharmacology to biomedical science.

New therapeutic strategies

Therapeutic potential of intrabodies
Targeting protein-protein interactions as a therapeutic strategy
The use of pluripotent stem cells in regenerative medicine
Quantitative systems pharmacology – is this the future of drug discovery?
Is germline CRISPR editing ready for the clinic?
Impact of big data on drug R&D and healthcare
Targeting virulence as a potential strategy for combating pathogenic bacteria
Pharmacological chaperones and their application in treating diseases

Challenging the dogma

Is aspirin a useful anti-thrombotic?
Are SSRIs really competitive inhibitors of SERT?
What are the mechanisms of drug entry in cells and tissues?
The relative significance of drugs and diet in influencing plasma lipid levels?

Understanding disease to guide therapy

The amyloid hypothesis and potential treatments for neurodegenerative diseases
Cystic fibrosis-related diabetes
The role of neutrophils in arterial thrombosis
What are the links between hypoxia and neurodegenerative diseases (e.g. Alzheimer’s disease)?
Is chronic visceral pain a manifestation of central or peripheral processes?
Bacterial host interactions in the development of chronic visceral pain: does early life exposure to pathogen influence pain sensitivity in adulthood?
Bacterial host interactions in cystic fibrosis

From molecular mechanism to drug target

Targeted degradation of CFTR: prospects for therapeutic interventions in CF
Duel glucagon and glucagon-like peptide 1 agonists as new treatments for type II diabetes
The structure of the exocytotic fusion pore
How do SNAREs mediate membrane fusion?
Trapping pain with TRPs: are TRP channels good targets for alleviating pain?
Pharmacological intervention in the cell cycle
Lipid transporters in health and disease
Store-operated calcium entry pathway as a potential therapeutic target
Cellular functions of Bax inhibitor-1
Can the naked mole-rat cure cancer?

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Pharmacology Thesis Topics for MD/DNB

Remember Subscribing to the premium thesis topics not only will enable you to browse through premium thesis topics but also you will get access to online guidance about synopsis writing, sample size calculation, inclusion and exclusion criteria and guidance throughout thesis writing. In case you dont subscribe still do not hesitate to contact me for guidance.

The effect of lamotrigine on working memory in rats.
Effectiveness of drug information pamphlets in improving patient medication adherence and usage of commonly prescribed medications and antibiotics among patients in a tertiary care hospital.
Study of prescription pattern of antihypertensive drugs in a tertiary care hospital.
A study to evaluate the antibacterial drugs used in upper-respiratory tract infection in pediatric age group.
Fluorouracil Degradation Rate (5-FUDR) as a predictive biomarker for adverse effects with 5- Fluorouracil / Capecitabine therapy in South Indian cancer patients – a prospective phenotype genotype association study.
Hepatoprotective effect of 7 – methoxy coumarin in paracetamol and ethanol toxicity induced cell lines.
Pattern of adverse drug reaction and medication use in neonatal care units in a tertiary care hospital: a longitudinal observational study.
Antidiabetic and pleiotropic effects of Psidium guajava Linn leaf extract. as an add on treatment in patients with type 2 diabetes mellitus – A randomized double-blind placebo controlled trial
Characterization of pncA mutation and treatment outcome among tuberculosis patients
Characterization of cyclosporine trough (C0) and two-hour post dose concentration (C2) monitoring in children with idiopathic nephrotic syndrome
Clinical characteristics and early outcome of bedaquiline containing regimens for the treatment of MDR
Clinical characteristics and treatment outcome of Isoniazid mono-resistance tuberculosis patients: A mixed-method study
ICMR Rational use of medicines “Evaluation of the prescription pattern of drugs in different OPDs of a tertiary care hospital” task force project
The cytokine levels and miRNA expression in patients with major depressive disorder and its modulation by silymarin.
Subclinical hypothyroidism and plasma levels of commonly prescribed antiepileptic drugs – a cross sectional study.
Pharmacogenetics of sodium valproate – induced weight gain in South Indian patients
Formulation and evaluation of topical preparation of Lawsonia inermis L. (Lythraceae) for the evaluation of Capecitabine induced hand – foot syndrome in cancer patients.
Are the users of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) at a higher risk of severe COVID-19? – A Case Control study.
Association of Nucleoside Diphosphate linked moiety X Type motif 15 (NUDT15) C415T and Inosine Triphosphate Pyrophosphatase (ITPA) C94A genetic polymorphisms with azathioprine induced adverse effects in south Indian patients.
Effect of VDR (Vitamin D Receptor) gene polymorphisms on efficacy of zoledronic acid in south Indian women with postmenopausal osteoporosis; A cross sectional study.
Cytogenetic and molecular characterization of teenage and young adult acute lymphoblastic leukaemia with special emphasis on identification of “Philadelphia like” profile
Influence of EPHX1 C and UGT2B7*2 genetic polymorphism on carbamazepine maintenance dose requirement in person with epilepsy .
Estimating Incremental Cost of treating Antimicrobial Resistant infections in India.
Study of prescription pattern of anti-epileptic agents in a tertiary care hospital.
Evaluation of anti-inflammatory and analgesic activities of thiophene derivatives in wistar albino rats
Evaluation of learning and memory enhancing activities of thiazolidinone arecoline derivatives in wistar albino rats.
Evaluation of hepatoprotective effect of gallic acid in murine model of isoniazid-induced hepatotoxicity.
Study of prescription pattern of Antimicrobial drugs in a tertiary care hospital.
Evaluation of effect of ciprofloxacin and levofloxacin on depressive behaviour in mice.
Evaluation of anti-ulcer activity of vanillin using stress and aspirin induced ulcer models in wistar albino rats
A comparative study of efficacy and safety of timolol versus latanoprost in the treatment of primary open angle glaucoma at a tertiary care hospital
A comparative prospective study to assess the efficacy and safety of iron sucrose versus iron sorbitol citric acid complex in pregnant women with iron deficiency anaemia in a tertiary care hospital
Comparison of the effects of imipramine and fluoxetine on the diagnostic parameters of metabolic syndrome in patients with depressive episode at a tertiary care hospital.
A comparitive study of efficacy and safety of intralesional triamcinolone with verapamilin treatment of keloid and hypertrophic scar in tertiary care hospital
A comparative study of the clinical efficacy and safety of topical retapamulin and mupirocin in the treatment of acute bacterial skin infections.
A prospective randomized open- labelled comparative study of the clinical efficacy and safety of the fixed dose combination of arterolane maleate and piperaquine phosphate with artesunate and sulfadoxine – pyrimethamine in uncomplicated falciparum malaria.
Prospective comparitive study of effect of two cephalosporin sulbactam combinations in chemoprophylaxis of open reduction & internal fixation surgery in closed limb fractures.
The efficacy and adverse drug profile of risperidone versus olanzapine in the treatment of patients with bipolar affective disorder on combination therapy – a prospective, naturalistic, hospital based clinical study.
Comparison of the effect of selective serotonin reuptake inhibitors and selective serotonin norepinephrine reuptake inhibitors on body mass index in patients on long term treatment.
Comparative assessment of the efficacy of morning dose versus evening dose levothyroxine in hypothyroid patients.
Study of prescription pattern of antitubercular drugs in a tertiary care hospital.
Comparative assessment of oral and local probiotics as an adjunct to standard therapy for vulvo vaginitis
Antiasthmatic effect of ethanolic extract of moringa oleifera (drumstick) seed kernels in an experimental animal mode.
Comparison of efficacy and safety of newer antifungal agent sertaconazole with clotrimazole and fluconazole in the treatment of acute vulvovaginal candidiasis.
Preliminary evaluation of anticonvulsant activity of aqueous extract of adhatoda vasica leaves in male and female albino rats.
Preliminary evaluation of hypoglycemic activity of methanol extract of roots of acorus calamus in alloxan induced diabetic albino rats.
To study effectiveness and tolerability of opipramol in the treatment of generalized anxiety disorder and somatoform disorders
A comparative study for efficacy `of combination therapy of inhaled levosalbutamol and ipratropium bromide against combination therapy of inhaled levosalbutamol and beclomethasone dipropionate in the treatment of bronchial asthma in adults
Monitoring and evaluation of adverse drug reactions in antiretroviraltherapy centre and dermatology department in a tertiary hospital
A prospective observational study on pattern of steroid utilization in a rural teaching hospital
A study of prescription pattern in musculoskeletal disorders causing low back pain(lbp) at kvg medical college, hospital,sullia,Karnataka
A study of prescription pattern in the drug therapy of rheumatoid arthrits at kvg medical college and hospital, sullia (d.k), karnataka.
A prospective study on the use of anaesthetic agents in modern surgical practice at k.v.g. medical college & hospital, sullia (d.k.), karnataka.
Adverse drug reaction monitoring in a teaching hospital, mandya.
Study of analgesics usage in third trimester of pregnancy and its illeffects on pregnancy course and outcome.
To evaluate the analgesic activity of garlic extract in rats.
A study to assess adverse drug reactions to anti retro viral therapy: type and risk factors in art centre at k. R. Hospital, mysore.
A randomized, prospective study of single dose epidural 0.2% levobupivacaine with 25µg fentanyl and single dose epidural 0.2% ropivacaine with 25µg fentanyl for post-operative analgesia in patients undergoing elective lower limb surgeries.
A prospective study of oral betahistine and ondansetron in the prevention of post operative nausea and vomiting, in patients undergoing tympanomastoid surgeries under local anaesthesia
Effect of minoxidil on blood glucose levels in normal and type 2 diabetic model of rats and its pharmacodynamic interation with glibenclamide: an experimental study
Prescription audit of antibacterials in suspected neonatal sepsis at a tertiary care hospital
Efficacy of supplementation of probiotics along with antimicrobial agents in vulvovaginal infections in a tertiary care hospital
Study of anticonvulsant effect of nebivolol in maximal electro shock (mes) and pentylenetetrazole (ptz) induced seizure models in mice
A prospective study to evaluate the effect of cilostazol on the lipid profile in patients of peripheral arterial disease as an adjunct to statins.
Experimental evaluation of anti convulsant activity of atorvastatin in wistar rats.
A randomised controlled study to compare the efficacy of racecadotril versus diphenoxylate in acute radiation enteritis.
Assessment of adverse drug reactions in geriatric patients in a tertiary care hospital
Factors affecting adherence to drugs and its influence on outcomes in select chronic disese (cardiovascular disease and diabetes mellitus at a tertiary care hospital
Patterns and determinants of poly pharmacy in perioperative patients in general surgical war ds of a tertiary care hospital: a prospective observational study
Pattern of use of analgesis for post-operative pain managment in adults undergoing laparotomy surgery-a prospective observational study in a tertiary care hospital
Patterns of drug use and factors affecting adherence to medication in rheumatoid arthritis- a prospective, observational, hospital based study
Study of prescription pattern in the management of herpes zoster at brims hospital, bidar
A comparative study of efficacy and safety of alternate day rosuvastatin dosing versus daily rosuvastatin dosing in patients with dyslipidemia”
Evaluation of the appropriateness of prescribing in geriatric patients admitted in various departments in government teaching hospital, bidar institute of medical sciences, bidar. Karnataka
A prospective study of various poisoning, pattern, pharmacological management and their outcome in a tertiary care hospital
Drug utilization study of antibiotics use in orthopaedic units of basaveshwar teaching and general hospital attached to hke society mahadevappa rampure medical college Gulbarga
A comparative study to evaluate the efficacy, tolerability and response rates of two antidepressants escitalopram with sertraline in patients of major depressive disorder.
Role of antimicrobial agents for the prevention of surgical site infections with pharmacoeconomics in the general surgery units.
A prospective study to compare efficacy and tolerability of ranolazine and nicorandil in the patients of angina pectoris.
Drug utilisation study of anticonvulsant agents in paediatric unit in a teritiary care hospital.
Comparative study of safety and efficacy of inhalation anti-asthma drugs versus systemic anti-asthma drugs in a tertiary care hospital.
Study of prescription pattern of antiemetic drugs in a tertiary care hospital.
A comparative study of antinociceptive activity of paroxitine with pethidine in acute pain in albino rats.
A comparative study of efficacy, tolerabilty and safety profile of fluoxetine with desvenlafaxine in patients with depression in a tertiary care hospital.
A comparative study of efficacy of silodosin and tamsulosin in patients of lower ureteric culculi in a tertiary care hospital
A prospective comparative efficacy & safety study of topical retapamulin and mupirocin.
A comparative study of the efficacy and safety of levocetirizine and rupatadine.
A comparative study of the efficacy and safety of amitryptyline and topiramate in the prophylaxis of migraine.
A comparative study of intravenous paracetamol and tramadol for post operative analgesic efficacy in orthopedic surgeries at a tertiary care hospital, bangalore.
Study of anti inflammatory activity of ficus racemosa linn stem bark extract in albino rats.
Study of analgesic activity of murraya koenigii leaves extractin albino mice.
A comparative study of the efficacy and safety of oral flunarizine to oral propranalol in prophylaxis of migraine .
A comparitive study of efficacy and tolerability of oral desloratadine, ketotifen and rupatadine in seasonal allergic rhinitis.
A study of the pattern of drug use for postoperative analgesia following lower abdominal surgeries in a tertiary care hospital.
Study of prescription pattern of oral contraceptive pills in a tertiary care hospital.
A study of the pattern of preanaesthetic medication for major surgeries under general anaesthesia in a tertiary care hospital
A comparative study of efficacy and tolerability of olopatadine, ketotifen and epinastine in seasonal allergic conjunctivitis.
A comparative study of efficacy and tolerability of methotrexate, sulfasalazine and leflunomide in rheumatoid arthritis.
A study of the pattern of drug use for general and regional anesthesia for caesarean section and to compare the maternal and neonatal outcome.
Adverse effects of anti tubercular treatment in cases of MDR tuberculosis.

Pharmacology & Toxicology Department Theses and Dissertations

Permanent uri for this collection.

About the programs

The advanced degree programs at the Indiana University of Medicine Department of Pharmacology and Toxicology prepare scientists for careers across the spectrum of biomedical research. The Master of Science (M.S.) degree is a thesis research degree that gives a student the intellectual background to understand and participate in ongoing research projects. The Doctor of Philosophy (Ph.D.) degree is offered for the student who wants to pursue an independent career in research. Students with the Ph.D. degree are prepared for an academic career combining research with teaching or for a career in industrial pharmaceutical research. A combined M.D./Ph.D. degree is open to qualified individuals who ultimately seek to direct biomedical research with a clinical emphasis.

For more information visit http://medicine.iu.edu/body.cfm?id=4418&oTopID=4418

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Home > FACULTIES > Physiology and Pharmacology > PHARMTOX-ETD

Pharmacology and Toxicology Theses and Dissertations

This collection contains theses and dissertations from the Department of Pharmacology and Toxicology, collected from the Scholarship@Western Electronic Thesis and Dissertation Repository

Theses/Dissertations from 2017 2017

The Effects of Acetylenic Tricyclic Bis-(Cyano Enone) on Cell Migration , Eddie Chan

Regulation of Cardiac Hypertrophy and Metabolism by Regulator of G Protein Signalling 2 (RGS2) , Katherine N. Lee

Theses/Dissertations from 2016 2016

Effects of Prenatal Exposure to Bisphenol A on Fetal Lung Development , Ayten Hijazi

Regulation of E2F1 in Keratinocytes During UV-Damage and Differentiation , Randeep K. Singh

Theses/Dissertations from 2015 2015

Quantitative Estimation of P-glycorptein-Mediated Drug Transport by Mechanistically Modeled Intrinsic Clearance , Alex D. Morgan

Epidermal Growth Factor Receptor in Joint Health and Osteoarthritis , Michael A. Pest

Regulation of Hepatic Drug Metabolizing Enzymes in Chronic Kidney Disease , Thomas J. Velenosi

Theses/Dissertations from 2014 2014

American Ginseng Modulation of Immune Function and Phytochemical Analysis , Chike G. Azike

Analysis of the Vascular Phenotype of the ENT1-null mouse , Keisha A. Best

Cortisol and Testosterone in Hair as Biological Markers of Systolic Heart Failure , Justin Chan

Regulation of the High-Affinity Choline Transporter Activity and Trafficking in Alzheimer’s Disease-Related Pathological Conditions , Leah K. Cuddy

Erythropoietin and Chronic Kidney Disease Alter Hepatic Expression of Cytochrome P450 Enzymes and Drug Transport Proteins , David A. Feere

The Role of c-Kit Receptor Tyrosine Kinase in Beta-Cell Proliferation, Function and Survival , Zhi Chao Feng

The Effects of Atypical Protein Kinase C on TGFβ Signalling , Adrian D. Gunaratne

Investigating Risk Factors for Pediatric Opioid Morbidity and Mortality , Lauren E. Kelly

Role Of Nitric Oxide In Embryonic Heart Development And Adult Aortic Valve Disease , Yin Liu

The ATP2C2 Gene as Transcribed from a Novel Transcriptional Start Site in Pancreatic Acinar Cells , Caitlin M. Sullivan

Effect of Ascorbate on Coagulation and Fibrinolytic Factors in the Septic Microvasculature , Scott Swarbreck

In Vitro Functional Analysis Of Novel Single Nucleotide Polymorphisms In OATP1B1 And Potential Clinical Relevance , Zhiyuan P. Yin

Theses/Dissertations from 2013 2013

Role of iNOS in septic pulmonary microvascular endothelial cell activation , Zahra Asad

ER stress coupled pannexin channel activation via STIM proteins , Ankur Bodalia

Pharmacogenetics of Oral Anticoagulants and Antiplatelets , Inna Gong

N-acetylcysteine as a chemoprotectant against ifosfamide nephrotoxicity; from mechanism to prevention , Lauren Hanly

Fetal and Neonatal Exposure to Nicotine Augments Hepatic Fatty Acid Synthesis in Rat Offspring Long-Term , Noelle L. Ma

Reorganization of inhibitory synapses in experimental epilepsy , Emily J. Pollock

Mechanism of Ascorbate Protection Against Sepsis-Induced Capillary Blood Flow Impairment , Dan Secor

Theses/Dissertations from 2012 2012

Statin Transport by Hepatic Organic Anion-Transporting Polypeptides (OATPs) , Marianne K. DeGorter

The Role of Drug Transporters in Statin-Induced Myopathy , Michael J. Knauer

The role of GRK2 in hypertension and regulation of GPR30 , Bonan Liu

Human Equilibrative Nucleoside Transporter Subtype 1: Structure-Function Analysis Using Cysteine Mutagenesis and Thiol Modifying Techniques , Jamie Park

Methodological Challenges and Clinical Applications of Hair Cortisol Analysis , Evan W. Russell

Intestinal and hepatic drug transporters and their role in the disposition of lipid-lowering drugs , Ute I. Schwarz

Molecular Mechanisms of Cell Migration Inhibition by Synthetic Triterpenoids , Ciric Chi Wing To

Characterization of EIF2Be and Its Interaction with RGS2 , William H. Xue

Theses/Dissertations from 2011 2011

Purine Transport and Metabolism in Microvascular Endothelial Cells , Derek B J Bone

Predicting Drug Hypersensitivity Reactions: Mechanistic and Clinical Implications , Abdelbaset A. Elzagallaai

Regulation of G Protein Signaling by GoLoco Motif Containing Proteins , Peishen Zhao

Theses/Dissertations from 2010 2010

Pharmacokinetics and Therapeutic Uses of Mesna , Murray J. Cutler

Regulation of DNA Damage Processing by Covalent Modification of Thymine DNA Glycosylase , Ryan D. Mohan

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1. The effect of lamotrigine on working memory in rats.

2. Effectiveness of drug information pamphlets in improving patient medication adherence and usage of commonly prescribed medications and antibiotics among patients in a tertiary care hospital.

3. Study of prescription pattern of antihypertensive drugs in a tertiary care hospital.

4. A study to evaluate the antibacterial drugs used in upper-respiratory tract infection in pediatric age group.

5. 5- Fluorouracil Degradation Rate (5-FUDR) as a predictive biomarker for adverse effects with 5- Fluorouracil / Capecitabine therapy in South Indian cancer patients – a prospective phenotype genotype association study.

6. Hepatoprotective effect of 7 – methoxy coumarin in paracetamol and ethanol toxicity induced cell lines.

7. Pattern of adverse drug reaction and medication use in neonatal care units in a tertiary care hospital: a longitudinal observational study.

8. Antidiabetic and pleiotropic effects of Psidium guajava Linn leaf extract. as an add on treatment in patients with type 2 diabetes mellitus – A randomized double-blind placebo controlled trial

9. Characterization of pncA mutation and treatment outcome among tuberculosis patients

10. Characterization of cyclosporine trough (C0) and two-hour post dose concentration (C2) monitoring in children with idiopathic nephrotic syndrome

11. Clinical characteristics and early outcome of bedaquiline containing regimens for the treatment of MDR

12. Clinical characteristics and treatment outcome of Isoniazid mono-resistance tuberculosis patients: A mixed-method study

13. ICMR Rational use of medicines “Evaluation of the prescription pattern of drugs in different OPDs of a tertiary care hospital” task force project

14. The cytokine levels and miRNA expression in patients with major depressive disorder and its modulation by silymarin.

15. Subclinical hypothyroidism and plasma levels of commonly prescribed antiepileptic drugs – a cross sectional study.

16. Pharmacogenetics of sodium valproate – induced weight gain in South Indian patients

17. Formulation and evaluation of topical preparation of Lawsonia inermis L. (Lythraceae) for the evaluation of Capecitabine induced hand – foot syndrome in cancer patients

18. Are the users of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) at a higher risk of severe COVID-19? – A Case Control study

19. Association of Nucleoside Diphosphate linked moiety X Type motif 15 (NUDT15) C415T and Inosine Triphosphate Pyrophosphatase (ITPA) C94A genetic polymorphisms with azathioprine induced adverse effects in south Indian patients.

20. Effect of VDR (Vitamin D Receptor) gene polymorphisms on efficacy of zoledronic acid in south Indian women with postmenopausal osteoporosis; A cross sectional study

21. Cytogenetic and molecular characterization of teenage and young adult acute lymphoblastic leukaemia with special emphasis on identification of “Philadelphia like” profile

22. Influence of EPHX1 c.337T>C and UGT2B7*2 genetic polymorphism on carbamazepine maintenance dose requirement in person with epilepsy from South Indi

23. Estimating Incremental Cost of treating Antimicrobial Resistant infections in India.

21. Study of prescription pattern of anti-epileptic agents in a tertiary care hospital

22. Evaluation of anti-inflammatory and analgesic activities of thiophene derivatives in wistar albino rats

23. Evaluation of learning and memory enhancing activities of thiazolidinone arecoline derivatives in wistar albino rats

24. Evaluation of hepatoprotective effect of gallic acid in murine model of isoniazid-induced hepatotoxicity.

25. Study of prescription pattern of Antimicrobial drugs in a tertiary care hospital.

26. Evaluation of effect of ciprofloxacin and levofloxacin on depressive behaviour in mice

27. Evaluation of anti-ulcer activity of vanillin using stress and aspirin induced ulcer models in wistar albino rats

28. A comparative study of efficacy and safety of timolol versus latanoprost in the treatment of primary open angle glaucoma at a tertiary care hospital

29. A comparative prospective study to assess the efficacy and safety of iron sucrose versus iron sorbitol citric acid complex in pregnant women with iron deficiency anaemia in a tertiary care hospital

30. Comparison of the effects of imipramine and fluoxetine on the diagnostic parameters of metabolic syndrome in patients with depressive episode at a tertiary care hospital

31. A comparitive study of efficacy and safety of intralesional triamcinolone with verapamilin treatment of keloid and hypertrophic scar in tertiary care hospital

32. A comparative study of the clinical efficacy and safety of topical retapamulin and mupirocin in the treatment of acute bacterial skin infections

33. A prospective randomized open- labelled comparative study of the clinical efficacy and safety of the fixed dose combination of arterolane maleate and piperaquine phosphate with artesunate and sulfadoxine – pyrimethamine in uncomplicated falcip

34. Prospective comparitive study of effect of two cephalosporin sulbactam combinations in chemoprophylaxis of open reduction & internal fixation surgery in closed limb fractures

35. The efficacy and adverse drug profile of risperidone versus olanzapine in the treatment of patients with bipolar affective disorder on combination therapy – a prospective, naturalistic, hospital based clinical study.

36. Comparison of the effect of selective serotonin reuptake inhibitors and selective serotonin norepinephrine reuptake inhibitors on body mass index in patients on long term treatment

37. Comparative assessment of the efficacy of morning dose versus evening dose levothyroxine in hypothyroid patients.

38. Study of prescription pattern of antitubercular drugs in a tertiary care hospital.

39. Comparative assessment of oral and local probiotics as an adjunct to standard therapy for vulvo vaginitis

40. “antiasthmatic effect of ethanolic extract of moringa oleifera (drumstick) seed kernels in an experimental animal model”.

41. Comparison of efficacy and safety of newer antifungal agent sertaconazole with clotrimazole and fluconazole in the treatment of acute vulvovaginal candidiasis.

42. Preliminary evaluation of anticonvulsant activity of aqueous extract of adhatoda vasica leaves in male and female albino rats

43. Preliminary evaluation of hypoglycemic activity of methanol extract of roots of acorus calamus in alloxan induced diabetic albino rats

44. To study effectiveness and tolerability of opipramol in the treatment of generalized anxiety disorder and somatoform disorders

45. A comparative study for efficacy `of combination therapy of inhaled levosalbutamol and ipratropium bromide against combination therapy of inhaled levosalbutamol and beclomethasone dipropionate in the treatment of bronchial asthma in adults

46. Monitoring and evaluation of adverse drug reactions in antiretroviraltherapy centre and dermatology department in a tertiary hospital

47. A prospective observational study on pattern of steroid utilization in a rural teaching hospital

48. A study of prescription pattern in musculoskeletal disorders causing low back pain(lbp) at kvg medical college, hospital,sullia,karnataka

49. A study of prescription pattern in the drug therapy of rheumatoid arthrits at kvg medical college and hospital, sullia (d.k), karnataka.

50. A prospective study on the use of anaesthetic agents in modern surgical practice at k.v.g. medical college & hospital, sullia (d.k.), karnataka.

51. Adverse drug reaction monitoring in a teaching hospital, mandya.

52. Study of analgesics usage in third trimester of pregnancy and its illeffects on pregnancy course and outcome.

53. To evaluate the analgesic activity of garlic extract in rats

54. A study to assess adverse drug reactions to anti retro viral therapy: type and risk factors in art centre at k. R. Hospital, mysore.

55. A randomized, prospective study of single dose epidural 0.2% levobupivacaine with 25µg fentanyl and single dose epidural 0.2% ropivacaine with 25µg fentanyl for post-operative analgesia in patients undergoing elective lower limb surgeries.

56. A prospective study of oral betahistine and ondansetron in the prevention of post operative nausea and vomiting, in patients undergoing tympanomastoid surgeries under local anaesthesia

57. Effect of minoxidil on blood glucose levels in normal and type 2 diabetic model of rats and its pharmacodynamic interation with glibenclamide: an experimental study

58. Prescription audit of antibacterials in suspected neonatal sepsis at a tertiary care hospital

59. Efficacy of supplementation of probiotics along with antimicrobial agents in vulvovaginal infections in a tertiary care hospital

60. Study of anticonvulsant effect of nebivolol in maximal electro shock (mes) and pentylenetetrazole (ptz) induced seizure models in mice

61. A prospective study to evaluate the effect of cilostazol on the lipid profile in patients of peripheral arterial disease as an adjunct to statins

62. Experimental evaluation of anti convulsant activity of atorvastatin in wistar rats

63. A randomised controlled study to compare the efficacy of racecadotril versus diphenoxylate in acute radiation enteritis.

64. Assessment of adverse drug reactions in geriatric patients in a tertiary care hospital

65. Factors affecting adherence to drugs and its influence on outcomes in select chronic disese (cardiovascular disease and diabetes mellitus at a tertiary care hospital

66. Patterns and determinants of poly pharmacy in perioperative patients in general surgical war ds of a tertiary care hospital: a prospective observational study

67. Pattern of use of analgesis for post-operative pain managment in adults undergoing laparotomy surgery-a prospective observational study in a tertiary care hospital

68. Patterns of drug use and factors affecting adherence to medication in rheumatoid arthritis- a prospective, observational, hospital based study

69. Study of prescription pattern in the management of herpes zoster at brims hospital, bidar

70. “a comparative study of efficacy and safety of alternate day rosuvastatin dosing versus daily rosuvastatin dosing in patients with dyslipidemia”

71. Evaluation of the appropriateness of prescribing in geriatric patients admitted in various departments in government teaching hospital, bidar institute of medical sciences, bidar. Karnataka

72. A prospective study of various poisoning, pattern, pharmacological management and their outcome in a tertiary care hospital

73. Drug utilization study of antibiotics use in orthopaedic units of basaveshwar teaching and general hospital attached to hke society mahadevappa rampure medical college gulbarga

74. A comparative study to evaluate the efficacy, tolerability and response rates of two antidepressants escitalopram with sertraline in patients of major depressive disorder.

75. Role of antimicrobial agents for the prevention of surgical site infections with pharmacoeconomics in the general surgery units.

76. A prospective study to compare efficacy and tolerability of ranolazine and nicorandil in the patients of angina pectoris at basaveshwara teaching and general hospital, gulbarga

77. Drug utilisation study of anticonvulsant agents in paediatric unit in a teritiary care hospital

78. Comparative study of safety and efficacy of inhalation anti-asthma drugs versus systemic anti-asthma drugs in a tertiary care hospital.

79. Study of prescription pattern of antiemetic drugs in a tertiary care hospital.

80. A comparative study of antinociceptive activity of paroxitine with pethidine in acute pain in albino rats

81. A comparative study of efficacy, tolerabilty and safety profile of fluoxetine with desvenlafaxine in patients with depression in a tertiary care hospital.

82. A comparative study of efficacy of silodosin and tamsulosin in patients of lower ureteric culculi in a tertiary care hospital

83. A prospective comparative efficacy & safety study of topical retapamulin and mupirocin

84. A comparative study of the efficacy and safety of levocetirizine and rupatadine

85. A comparative study of the efficacy and safety of amitryptyline and topiramate in the prophylaxis of migraine

86. A comparative study of intravenous paracetamol and tramadol for post operative analgesic efficacy in orthopedic surgeries at a tertiary care hospital, bangalore

87. Study of anti inflammatory activity of ficus racemosa linn stem bark extract in albino rats

88. Study of analgesic activity of murraya koenigii leaves extractin albino mice

89. A comparative study of the efficacy and safety of oral flunarizine to oral propranalol in prophylaxis of migraine in rajarajeswari medical college and hospital bangalore

90. A comparitive study of efficacy and tolerability of oral desloratadine, ketotifen and rupatadine in seasonal allergic rhinitis

91. A study of the pattern of drug use for postoperative analgesia following lower abdominal surgeries in a tertiary care hospital.

92. Study of prescription pattern of oral contraceptive pills in a tertiary care hospital.

93. A study of the pattern of preanaesthetic medication for major surgeries under general anaesthesia in a tertiary care hospital

94. A comparative study of efficacy and tolerability of olopatadine, ketotifen and epinastine in seasonal allergic conjunctivitis

95. A comparative study of efficacy and tolerability of methotrexate, sulfasalazine and leflunomide in rheumatoid arthritis

96. A study of the pattern of drug use for general and regional anesthesia for caesarean section and to compare the maternal and neonatal outcome

97. Evaluation of nephroprotective action of ethanolic extract of leaves of alocasia macrorrhizos in rats

98. Study of prescription patterns and pharmacoeconomic evaluation of anti-epileptic drugs

99. A prospective study on pattern of poisoning among adult in-patients in a tertiary care hospital.

100. Evaluation of Glycemic Index and Insulin Index of a marketed sugar product.

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How to get through the MPharm dissertation

The MPharm dissertation is one of the longest pieces of writing we create as pharmacy students. I remember feeling quite anxious about it all. I wasn’t too sure how I was going to write 10,000 words on a topic which at the time I had no idea about, however once I got into it, I really enjoyed writing my dissertation.

The dissertation is usually a lengthy process composed of weeks filled with intense research, several draft versions, blog entries, and supervisory meetings. I was fortunate enough to get a research project in the area of pharmacy education. My project focused on student learning in integrated pharmacy curricular. At the time of receiving my title I wasn’t sure what to expect, but I was intrigued to see what developed once I started. I began my dissertation by conducting a literature search which allowed me to access the plethora of literature available within the field of pharmacy education. I made sure my literature search was as specific as possible to ensure the papers were relevant and accurate for the research topic. I remember when I would hear or read ‘buzz words’ like ‘integrated’ or ‘curriculum’ my ears would crop up and my eyes would become fixed on the particular article. It was also ironic that during the end of my dissertation the GPhC consultation on the initial education and training standards for pharmacists began. However, the MPharm dissertation is not always plain sailing and everyone’s experience varies, here I share four-tips which helped me get through the MPharm dissertation. I hope they will be useful for MPharm students starting their dissertation.

Firstly, organisation. Dissertation deadlines may seem like a long time away, but make sure you are aware of your deadline and start planning in advance. Within a qualitative research project, you may need to conduct interviews or focus groups with participants, and therefore ethical approval is necessary before you start data collection. This process can sometimes take a couple of weeks and slightly delay data collection, so it’s important to account for this. The best way I found to organise my time was by making lists and drafting a timeline or timetable. Aim to plan each week and write down what you want to get out from that week. It’s important to have a clear and coherent plan to keep on top of things, just make sure you know what your aiming for each week. Don’t worry too much if you don’t meet your plan or something else comes in the way that’s normal, but just getting into a habit of planning is really good. You can use post-it notes, diaries or the reminders app on your phone to maintain your progress.

Secondly, don’t panic. This is sometimes easier said than done. The dissertation can sometimes be stressful so try and be enthusiastic and remain positive. Speak to your peers, supervisor or module co-ordinator if you’re feeling overwhelmed, they will be more than happy to re-assure you that everything’s ok. There are also organisations like pharmacist support who can help you if you’re feeling like you just need to speak to someone anonymously.

Thirdly, work hard play hard. Make sure you give yourself at least one day of the week where you don’t think about your dissertation. For me personally this was Friday. I used this time to go out and see friends and visit the new restaurants and cafes that had opened in Newcastle. This was a great way for me to catch up with all my university friends who I would rarely see during the week. This becomes more important nearer to the end of your dissertation, as you will notice your stress levels increase, and you get a lot of encouragement from your peers to keep soldiering on.

Lastly, Enjoy it! Although the dissertation can sometimes feel overwhelming, the skills you learn from the MPharm dissertation are invaluable and the process is a real learning curve. You definitely strengthen your friendship groups during this time but also build good rapport with your supervisor. Once you have your dissertation printed and bound in your hands the surge of pride and achievement is just indescribable, and you soon realise that the good times at university are coming to an end.

About the author:

Ausaf Hayat Khan, recently completed his MPharm at Newcastle university. He will soon be pursuing his preregistration training within the hospital sector and will be presenting his dissertation at the 10th Biennial Monash Pharmacy Education Symposium 2019.

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Home > Eppley Institute > Theses & Dissertations

Theses & Dissertations: Cancer Research

Theses/dissertations from 2024 2024.

Therapeutic Effects of BET Protein Inhibition in B-cell Malignancies and Beyond , Audrey L. Smith

Identification of Mitotic Phosphatases and Cyclin K as Novel Molecular Targets in Pancreatic Cancer , Yi Xiao

Theses/Dissertations from 2023 2023

Development of Combination Therapy Strategies to Treat Cancer Using Dihydroorotate Dehydrogenase Inhibitors , Nicholas Mullen

Overcoming Resistance Mechanisms to CDK4/6 Inhibitor Treatment Using CDK6-Selective PROTAC , Sarah Truong

Theses/Dissertations from 2022 2022

Omics Analysis in Cancer and Development , Emalie J. Clement

Investigating the Role of Splenic Macrophages in Pancreatic Cancer , Daisy V. Gonzalez

Polymeric Chloroquine in Metastatic Pancreatic Cancer Therapy , Rubayat Islam Khan

Evaluating Targets and Therapeutics for the Treatment of Pancreatic Cancer , Shelby M. Knoche

Characterization of 1,1-Diarylethylene FOXM1 Inhibitors Against High-Grade Serous Ovarian Carcinoma Cells , Cassie Liu

Novel Mechanisms of Protein Kinase C α Regulation and Function , Xinyue Li

SOX2 Dosage Governs Tumor Cell Identity and Proliferation , Ethan P. Metz

Post-Transcriptional Control of the Epithelial-to-Mesenchymal Transition (EMT) in Ras-Driven Colorectal Cancers , Chaitra Rao

Use of Machine Learning Algorithms and Highly Multiplexed Immunohistochemistry to Perform In-Depth Characterization of Primary Pancreatic Tumors and Metastatic Sites , Krysten Vance

Characterization of Metastatic Cutaneous Squamous Cell Carcinoma in the Immunosuppressed Patient , Megan E. Wackel

Visceral adipose tissue remodeling in pancreatic ductal adenocarcinoma cachexia: the role of activin A signaling , Pauline Xu

Phos-Tag-Based Screens Identify Novel Therapeutic Targets in Ovarian Cancer and Pancreatic Cancer , Renya Zeng

Theses/Dissertations from 2021 2021

Functional Characterization of Cancer-Associated DNA Polymerase ε Variants , Stephanie R. Barbari

Pancreatic Cancer: Novel Therapy, Research Tools, and Educational Outreach , Ayrianne J. Crawford

Apixaban to Prevent Thrombosis in Adult Patients Treated With Asparaginase , Krishna Gundabolu

Molecular Investigation into the Biologic and Prognostic Elements of Peripheral T-cell Lymphoma with Regulators of Tumor Microenvironment Signaling Explored in Model Systems , Tyler Herek

Utilizing Proteolysis-Targeting Chimeras to Target the Transcriptional Cyclin-Dependent Kinases 9 and 12 , Hannah King

Insights into Cutaneous Squamous Cell Carcinoma Pathogenesis and Metastasis Using a Bedside-to-Bench Approach , Marissa Lobl

Development of a MUC16-Targeted Near-Infrared Antibody Probe for Fluorescence-Guided Surgery of Pancreatic Cancer , Madeline T. Olson

FGFR4 glycosylation and processing in cholangiocarcinoma promote cancer signaling , Andrew J. Phillips

Theses/Dissertations from 2020 2020

Cooperativity of CCNE1 and FOXM1 in High-Grade Serous Ovarian Cancer , Lucy Elge

Characterizing the critical role of metabolic and redox homeostasis in colorectal cancer , Danielle Frodyma

Genomic and Transcriptomic Alterations in Metabolic Regulators and Implications for Anti-tumoral Immune Response , Ryan J. King

Dimers of Isatin Derived Spirocyclic NF-κB Inhibitor Exhibit Potent Anticancer Activity by Inducing UPR Mediated Apoptosis , Smit Kour

From Development to Therapy: A Panoramic Approach to Further Our Understanding of Cancer , Brittany Poelaert

The Cellular Origin and Molecular Drivers of Claudin-Low Mammary Cancer , Patrick D. Raedler

Mitochondrial Metabolism as a Therapeutic Target for Pancreatic Cancer , Simon Shin

Development of Fluorescent Hyaluronic Acid Nanoparticles for Intraoperative Tumor Detection , Nicholas E. Wojtynek

Theses/Dissertations from 2019 2019

The role of E3 ubiquitin ligase FBXO9 in normal and malignant hematopoiesis , R. Willow Hynes-Smith

BRCA1 & CTDP1 BRCT Domainomics in the DNA Damage Response , Kimiko L. Krieger

Targeted Inhibition of Histone Deacetyltransferases for Pancreatic Cancer Therapy , Richard Laschanzky

Human Leukocyte Antigen (HLA) Class I Molecule Components and Amyloid Precursor-Like Protein 2 (APLP2): Roles in Pancreatic Cancer Cell Migration , Bailee Sliker

Theses/Dissertations from 2018 2018

FOXM1 Expression and Contribution to Genomic Instability and Chemoresistance in High-Grade Serous Ovarian Cancer , Carter J. Barger

Overcoming TCF4-Driven BCR Signaling in Diffuse Large B-Cell Lymphoma , Keenan Hartert

Functional Role of Protein Kinase C Alpha in Endometrial Carcinogenesis , Alice Hsu

Functional Signature Ontology-Based Identification and Validation of Novel Therapeutic Targets and Natural Products for the Treatment of Cancer , Beth Neilsen

Elucidating the Roles of Lunatic Fringe in Pancreatic Ductal Adenocarcinoma , Prathamesh Patil

Theses/Dissertations from 2017 2017

Metabolic Reprogramming of Pancreatic Ductal Adenocarcinoma Cells in Response to Chronic Low pH Stress , Jaime Abrego

Understanding the Relationship between TGF-Beta and IGF-1R Signaling in Colorectal Cancer , Katie L. Bailey

The Role of EHD2 in Triple-Negative Breast Cancer Tumorigenesis and Progression , Timothy A. Bielecki

Perturbing anti-apoptotic proteins to develop novel cancer therapies , Jacob Contreras

Role of Ezrin in Colorectal Cancer Cell Survival Regulation , Premila Leiphrakpam

Evaluation of Aminopyrazole Analogs as Cyclin-Dependent Kinase Inhibitors for Colorectal Cancer Therapy , Caroline Robb

Identifying the Role of Janus Kinase 1 in Mammary Gland Development and Breast Cancer , Barbara Swenson

DNMT3A Haploinsufficiency Provokes Hematologic Malignancy of B-Lymphoid, T-Lymphoid, and Myeloid Lineage in Mice , Garland Michael Upchurch

Theses/Dissertations from 2016 2016

EHD1 As a Positive Regulator of Macrophage Colony-Stimulating Factor-1 Receptor , Luke R. Cypher

Inflammation- and Cancer-Associated Neurolymphatic Remodeling and Cachexia in Pancreatic Ductal Adenocarcinoma , Darci M. Fink

Role of CBL-family Ubiquitin Ligases as Critical Negative Regulators of T Cell Activation and Functions , Benjamin Goetz

Exploration into the Functional Impact of MUC1 on the Formation and Regulation of Transcriptional Complexes Containing AP-1 and p53 , Ryan L. Hanson

DNA Polymerase Zeta-Dependent Mutagenesis: Molecular Specificity, Extent of Error-Prone Synthesis, and the Role of dNTP Pools , Olga V. Kochenova

Defining the Role of Phosphorylation and Dephosphorylation in the Regulation of Gap Junction Proteins , Hanjun Li

Molecular Mechanisms Regulating MYC and PGC1β Expression in Colon Cancer , Jamie L. McCall

Pancreatic Cancer Invasion of the Lymphatic Vasculature and Contributions of the Tumor Microenvironment: Roles for E-selectin and CXCR4 , Maria M. Steele

Altered Levels of SOX2, and Its Associated Protein Musashi2, Disrupt Critical Cell Functions in Cancer and Embryonic Stem Cells , Erin L. Wuebben

Theses/Dissertations from 2015 2015

Characterization and target identification of non-toxic IKKβ inhibitors for anticancer therapy , Elizabeth Blowers

Effectors of Ras and KSR1 dependent colon tumorigenesis , Binita Das

Characterization of cancer-associated DNA polymerase delta variants , Tony M. Mertz

A Role for EHD Family Endocytic Regulators in Endothelial Biology , Alexandra E. J. Moffitt

Biochemical pathways regulating mammary epithelial cell homeostasis and differentiation , Chandrani Mukhopadhyay

EPACs: epigenetic regulators that affect cell survival in cancer. , Catherine Murari

Role of the C-terminus of the Catalytic Subunit of Translesion Synthesis Polymerase ζ (Zeta) in UV-induced Mutagensis , Hollie M. Siebler

LGR5 Activates TGFbeta Signaling and Suppresses Metastasis in Colon Cancer , Xiaolin Zhou

LGR5 Activates TGFβ Signaling and Suppresses Metastasis in Colon Cancer , Xiaolin Zhou

Theses/Dissertations from 2014 2014

Genetic dissection of the role of CBL-family ubiquitin ligases and their associated adapters in epidermal growth factor receptor endocytosis , Gulzar Ahmad

Strategies for the identification of chemical probes to study signaling pathways , Jamie Leigh Arnst

Defining the mechanism of signaling through the C-terminus of MUC1 , Roger B. Brown

Targeting telomerase in human pancreatic cancer cells , Katrina Burchett

The identification of KSR1-like molecules in ras-addicted colorectal cancer cells , Drew Gehring

Mechanisms of regulation of AID APOBEC deaminases activity and protection of the genome from promiscuous deamination , Artem Georgievich Lada

Characterization of the DNA-biding properties of human telomeric proteins , Amanda Lakamp-Hawley

Studies on MUC1, p120-catenin, Kaiso: coordinate role of mucins, cell adhesion molecules and cell cycle players in pancreatic cancer , Xiang Liu

Epac interaction with the TGFbeta PKA pathway to regulate cell survival in colon cancer , Meghan Lynn Mendick

Theses/Dissertations from 2013 2013

Deconvolution of the phosphorylation patterns of replication protein A by the DNA damage response to breaks , Kerry D. Brader

Modeling malignant breast cancer occurrence and survival in black and white women , Michael Gleason

The role of dna methyltransferases in myc-induced lymphomagenesis , Ryan A. Hlady

Design and development of inhibitors of CBL (TKB)-protein interactions , Eric A. Kumar

Pancreatic cancer-associated miRNAs : expression, regulation and function , Ashley M. Mohr

Mechanistic studies of mitochondrial outer membrane permeabilization (MOMP) , Xiaming Pang

Novel roles for JAK2/STAT5 signaling in mammary gland development, cancer, and immune dysregulation , Jeffrey Wayne Schmidt

Optimization of therapeutics against lethal pancreatic cancer , Joshua J. Souchek

Theses/Dissertations from 2012 2012

Immune-based novel diagnostic mechanisms for pancreatic cancer , Michael J. Baine

Sox2 associated proteins are essential for cell fate , Jesse Lee Cox

KSR2 regulates cellular proliferation, transformation, and metabolism , Mario R. Fernandez

Discovery of a novel signaling cross-talk between TPX2 and the aurora kinases during mitosis , Jyoti Iyer

Regulation of metabolism by KSR proteins , Paula Jean Klutho

The role of ERK 1/2 signaling in the dna damage-induced G2 , Ryan Kolb

Regulation of the Bcl-2 family network during apoptosis induced by different stimuli , Hernando Lopez

Studies on the role of cullin3 in mitosis , Saili Moghe

Characteristics of amyloid precursor-like protein 2 (APLP2) in pancreatic cancer and Ewing's sarcoma , Haley Louise Capek Peters

Structural and biophysical analysis of a human inosine triphosphate pyrophosphatase polymorphism , Peter David Simone

Functions and regulation of Ron receptor tyrosine kinase in human pancreatic cancer and its therapeutic applications , Yi Zou

Theses/Dissertations from 2011 2011

Coordinate detection of new targets and small molecules for cancer therapy , Kurt Fisher

The role of c-Myc in pancreatic cancer initiation and progression , Wan-Chi Lin

The role of inosine triphosphate pyrophosphatase (ITPA) in maintanence [sic] of genomic stability in human cells , Miriam-Rose Menezes

Molecular insights into major histocompatibility complex class I folding and assembly , Laura Christina Simone

The role of bcl-2 in colon cancer metastatic progression , Wang Wang

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There is no regulation for the length of a thesis, but a thesis must contain ALL components (see below). There is great variation in the length of theses, but in Pharmacology, most MSc theses range from 75 - 100 pages; and most PhD theses range from 150 - 250 pages. Ph.D. and M.Sc. thesis manuscripts should be written under the following
Pharmacology & Toxicology Department Theses and Dissertations
The advanced degree programs at the Indiana University of Medicine Department of Pharmacology and Toxicology prepare scientists for careers across the spectrum of biomedical research. The Master of Science (M.S.) degree is a thesis research degree that gives a student the intellectual background to understand and participate in ongoing research ...
Pharmacology and Toxicology Theses and Dissertations
This collection contains theses and dissertations from the Department of Pharmacology and Toxicology, ... Theses/Dissertations from 2017 PDF. The Effects of Acetylenic Tricyclic Bis-(Cyano Enone) on Cell Migration, Eddie Chan. PDF. Regulation of Cardiac Hypertrophy and Metabolism by Regulator of G Protein Signalling 2 (RGS2), Katherine N. Lee.
Clinical Pharmacology Dissertation Topics
Clinical Pharmacology Dissertation Topics - Free download as PDF File (.pdf), Text File (.txt) or read online for free. Scribd is the world's largest social reading and publishing site.
Pharmacology Thesis Topics for MD/DNB
Pharmacology Thesis/Dissertation Topics for MD/DNB. 1. The effect of lamotrigine on working memory in rats. 2. Effectiveness of drug information pamphlets in improving patient medication adherence and usage of commonly prescribed medications and antibiotics among patients in a tertiary care hospital. 3.
How to get through the MPharm dissertation
However, the MPharm dissertation is not always plain sailing and everyone's experience varies, here I share four-tips which helped me get through the MPharm dissertation. I hope they will be useful for MPharm students starting their dissertation. Firstly, organisation. Dissertation deadlines may seem like a long time away, but make sure you ...
Theses & Dissertations: Cancer Research
Theses/Dissertations from 2015. Characterization and target identification of non-toxic IKKβ inhibitors for anticancer therapy, Elizabeth Blowers. Effectors of Ras and KSR1 dependent colon tumorigenesis, Binita Das. Characterization of cancer-associated DNA polymerase delta variants, Tony M. Mertz.
Hot Topics in Pharmaceutical Research
Hot Topics in Pharmaceutical Research. In this virtual issue, we highlight some of the most impactful recent articles in the journal as reflected by citations in 2022. Highly cited articles provide insight into which research topics are attracting the most attention and reflect innovative new discoveries, or timely reviews and perspectives on ...
clinical pharmacology research: Topics by Science.gov
Lessons learned from the past: a guide for the future of clinical pharmacology in the 21st century.. PubMed. Lathers, C M. 2000-09-01. This article is a documentary of the history of the American College of Clinical Pharmacology (ACCP) and the Journal of Clinical Pharmacology.The history of the college and of the journal is presented as summarized by a few of the many leaders who played key ...
Pharmacology Dissertations
Dissertations on Pharmacology. Pharmacology involves the study of drugs and how they affect the body. A pharmacologist contributes to drug development by researching and testing how the body reacts to medication, and whether the medication can have a positive impact on the body in terms of fighting illness and disease. View All Dissertation ...
Dissertation topics for MD Pharmacology
32. A STUDY TO ASSESS ADVERSE DRUG REACTIONS TO ANTI RETRO VIRAL THERAPY: TYPE AND RISK FACTORS IN ART CENTRE AT K. R. HOSPITAL, MYSORE. GOVERNMENT MEDICAL COLLEGE,, MYSORE. 33. A RANDOMIZED, PROSPECTIVE STUDY OF SINGLE DOSE EPIDURAL 0.2% LEVOBUPIVACAINE WITH 25µG FENTANYL AND SINGLE DOSE EPIDURAL 0.2% ROPIVACAINE WITH 25µG FENTANYL FOR POST ...
MD Pharmacology thesis topics MMC
THESIS TITLE. MONTH & YEAR. 1. A Study on the efficacy and tolerability of pentoxifylline in alcoholic hepatitis. Mar 2010. 2. Efficacy and tolerability of Atorvastatin as an add on therapy in the treatment of chronic stable (moderate-severe) asthma. Mar 2009. 3.

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Clinical Pharmacology: Current Topics and Case Studies

Department of Clinical Pharmacology, Medical University Vienna, Vienna General Hospital (AKH), Vienna, Austria

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Table of contents (26 chapters)

Current issues in drug development

Current issues in drug reimbursement

Clinical Trials

Good Clinical Practice (GCP) and scientific misconduct

Phase-I studies and first-in-human trials

Clinical trials - interventional studies

Observational studies

Pharmacokinetics I: PK-PD approaches - antibiotic drug development

Pharmacokinetics II: 14C-labelled microdosing in assessing drug pharmacokinetics at Phase-0

Epidemiology and bio statistics

Placebo effects and placebo control in clinical trials