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Introduction

Theses and dissertations are documents that present an author's research findings, which are submitted to the University in support of their academic degree. They are very useful to consult when carrying out your own research because they:

• provide a springboard to scope existing literature
• provide inspiration for the finished product
• show you the evolution of an author's ideas over time
• provide relevant and up-to-date research (for recent theses and dissertations)

On this page you will find guidance on how to search for and access theses and dissertations in the Bodleian Libraries and beyond.

Definitions

Terms you may encounter in your research.

Thesis: In the UK, a thesis is normally a document that presents an author's research findings as part of a doctoral or research programme.

Dissertation: In the UK, a dissertation is normally a document that presents an author's research findings as part of an undergraduate or master's programme.

DPhil: An abbreviation for Doctor of Philosophy, which is an advanced research qualification. You may also see it referred to as PhD.

ORA: The Oxford University Research Archive , an institutional repository for the University of Oxford's research output including digital theses.

Theses and dissertations

• Reading theses and dissertations in the Bodleian Libraries

The Bodleian Libraries collection holds DPhil, MLitt and MPhil theses deposited at the University of Oxford, which you can consult. You may also be interested to read theses and dissertations beyond the University of Oxford, some of which can be read online, or you can request an inter-library loan.

Help with theses and dissertations

To find out more about how to find and access theses and dissertations in the Bodleian Libraries and beyond, we recommend the following:

• Bodleian Libraries theses and dissertations Links to information on accessing the Bodleian Libraries collections of Oxford, UK, US and other international theses.
• Oxford University Research Archive guide
• Help & guidance for digital theses Information on copyright, how to deposit your thesis in ORA and other important matters
• Guide to copyright The Bodleian Libraries' Quick guide to copyright and digital sources.

Plagiarism checking tools

Read the University academic good practice page.

Seek your Supervisor or Tutor's guidance. In addition, your Supervisor or Tutor may decide to submit your work to Turnitin, accessible to teaching staff only. Visit the Turnitin website for product information.

Consult books - suggested reading:

• Neville, C. (2016). The complete guide to referencing and avoiding plagiarism (3rd ed.).  Maidenhead: Open University Press. Title available in e-book and print format - shelfmark PN171.F56 NEV 2016 in the Radcliffe Science Library 
• Pears, R. & Shields, G.J. (2019). Cite them right: the essential referencing guide (11th ed.) Basingstoke: Palgrave Macmillan. Title available in e-book format

Depositing your thesis

It is mandatory for students completing a research degree at the University of Oxford (registered to a programme of study on or after 1st October 2007) to deposit an electronic copy of their theses with the Oxford University Research Archive (ORA) in order to meet the requirements of their award. To find out more, visit the Oxford University Research Archive guide.

Quick access to research & writing guides

• Research integrity and ethics The University of Oxford regards research integrity as a core value and has a longstanding commitment to ensuring that it is embedded in its research culture and activity
• Academic good practice Advice on academic good practice including avoiding plagiarism, managing your time, reading, note taking, referencing and revision.
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Home > Sciences > Biomedical Sciences ETDs

Theses and Dissertations in Biomedical Sciences

Theses/dissertations from 2015 2015.

Dissertation: The Effects of Propofol, Sodium Pentobarbital, and Ketamine Hydrochloride on In Vitro Mouse Embryonic Development , Tyler C. Balak

Dissertation: Investigation Into Protein Folding and Misfolding , Jason Charles Collins

Dissertation: Exploring the Neuropeptides, Neuropeptide Receptors and Neurotransmitter Receptors in the Synganglia of Part-Fed Females of Ornithodoros turicata (Argasidae) and Ixodes scapularis (Ixodidae) with Insights Into Their Roles in Contrasting Biology , Noble I. Egekwu

Theses/Dissertations from 2014 2014

Dissertation: Mouse Oocyte Maturation and Embryo Development After Exposure to Vemurafenib (PLX4032), an Anti-Melanoma B-RAF V600E Inhibitor , Bo Liu

Dissertation: Experimental and Computational Analysis of the Synucleins , Agatha Munyanyi

Theses/Dissertations from 2013 2013

Dissertation: New Tools for Real-Time Study of Embryonic Development , Lauren M. Browning

Dissertation: Structural and Functional Study of Multidrug Membrane Transporters , Feng Ding

Dissertation: Attachment Ability and Melanoma Inhibitory Activity mRNA Expression Level Changes in Murine B16-F10 Melanoma Cells Post Nanosecond Electric Pulses , Hongxia Jia

Dissertation: New Types of Morpho-Physiological Changes in Cells Exposed to Nanosecond Pulsed Electric Field , Mikhail A. Rassokhin

Theses/Dissertations from 2012 2012

Dissertation: Nano- and Micro-Second Electrical Pulsing of B16-F10 Mouse Melanoma Cells: Plasma Membrane and Sub-Cellular Organelle Changes , Yiling Chen

Dissertation: Treatment of Aortic Heart Valve Conduit with Glutamine and Heat Shock as a Means to Deter the Constituent Cellular Population From Becoming Apoptotic , Alyce Marie Linthurst Jones

Dissertation: Design of In Vivo Assays for Study of Transport, Biocompatibility and Toxicity of Nanoparticles , Kerry Jean Lee

Dissertation: The Dietary Isoprenoid Perillyl Alcohol Inhibits Telomerase Activity in Prostate Cancer Cells , Tabetha Sundin

Theses/Dissertations from 2011 2011

Dissertation: Age-Related Hamster Mitochondrial Changes and Oocyte Changes Following Autologous Platelet Mitochondrial Microinjection , Fang Li

Dissertation: Nanosecond Pulsed Electric Field Induction of Programmed Cell Death Is Cell Type Dependent: An in vitro Study , Wei Ren

Dissertation: Altering Nitric Oxide Bioavailability and Lipid Profiles in Endothelial Cells By Polycyclic Aromatic Hydrocarbons in Particulate Matter , Liang Yu

Theses/Dissertations from 2010 2010

Dissertation: Group II Metabolic Glutamate Receptors in the Basal Amygdala Regulate Sleep and Fear-Induced Alterations in Sleep , Enheng Dong

Dissertation: Organization of Human Sperm Chromosomes During Pronuclei Formation , Estella Jones

Dissertation: Cellular Immunity in Mouse Models of Viral Encephalitis , Christina Dawn Steel

Dissertation: The Effects of Cocaine and Ecstasy on Cardiac Myocytes and the Intact Myocardium , David A. Tiangco

Dissertation: Characterization of Metastasis-Associated Cell Surface Glycoproteins in Prostate Cancer , Lifang Yang

Theses/Dissertations from 2009 2009

Dissertation: Mechanisms of Regulation of Proximal Tubule Sodium Transporters in Obesity-Induced Hypertension , Marta A. Ambrozewicz

Dissertation: Comparison of Immune Correlates, Age Related Changes and Proteomic Profiling of Healthy Individuals Receiving Influenza Vaccines , Gaurav Basu

Dissertation: Study of the DNA Damage Complexes Within the HTLV-1 Tax Oncoprotein Interactome , Sidi Mehdi Belgnaoui

Dissertation: Interdependent Regulation of Cytomegalovirus Proteins in Complex , Lisa L. Bolin

Dissertation: Role of the Human Cytomegalovirus IE2 Protein on Transcriptional Regulation of Viral Promoters , Siabhon Michelle Harris

Dissertation: Phosphorylation of the Estrogen Receptor Alpha (ERα) at Serine 118 by Phospho-p44/42 MAPK and Regulation by Estrogen and Progesterone in Human Uterine Leiomyoma Tissue and Cells , Tonia Lakisha Hermon

Dissertation: Effects of HZE Irradiation on Chemical Neurotransmission in Rodent Hippocampus , Mayumi Machida

Dissertation: Molecular Dynamics Study of Single Stranded Peptide Nucleic Acids , Anna K. Manukyan

Dissertation: Computational Studies on R67 Dihydrofolate Reductase: An Investigation Into Its Unique Binding Patterns , Chuanyin Shi

Dissertation: Analysis of N-Linked Oligosaccharides of Prostate-Specific Antigen and Prostatic Acid Phosphatase in Prostatic Fluids , Krista Yaudes White

Theses/Dissertations from 2008 2008

Dissertation: MALDI Mass Spectrometry Imaging for the Discovery of Prostate Carcinoma Biomarkers , Lisa Harris Cazares

Dissertation: In Vivo Murine Melanoma Tumor Responses to Nanosecond Pulsed Electric Field Treatment , Xinhua Chen

Dissertation: Nanosecond Pulsed Electric Fields Induce a Mitochondria-Independent Apoptosis in B16F10 Melanoma Cells In Vitro , Wentia Elissa Ford

Dissertation: Subcellular Localization of Human T-cell Leukemia Virus Type 1 Tax Oncoprotein , Kimberly Anne Fryrear

Dissertation: The Application of Innovative High-Throughput Techniques to Serum Biomarker Discovery , Izabela Debkiewicz Karbassi

Dissertation: PGE2 Receptor Subsets Mediate HCG Regulation of the Plasminogen Activator/Plasmin System in Primate Periovulatory Follicles , Nune Markosyan

Dissertation: Cannabinoids: A Novel Treatment Strategy for Retinal Neurodegenerative Disorders , Sandeep Samudre

Dissertation: Gene Therapy Using Tet-Repressor System to Modulate Prostate Tumor Microenvironment , Nazita Yousefieh

Theses/Dissertations from 2007 2007

Dissertation: Down-Regulation of Natural Killer Cell Activation in Response to Influenza Virus in Older Adults , Yu Jing

Dissertation: Serotype Association and Regulation of the Hyaluronate Lyase Gene of Streptococcus pyogenes , Martha Stokes

Theses/Dissertations from 2006 2006

Dissertation: Extracellular Superoxide Dismutase Protects Cardiomyocytes During Hyperoxia , Mervat Elsayed Ali

Dissertation: Isolation and Functional Mapping of Human T-Cell Leukemia Virus Type 1 Tax Oncoprotein DNA-Damage Complexes , Sarah Saionz Durkin

Dissertation: Nanosecond Pulsed Electric Field Effects on Cell Cycle and Apoptosis , Emily H. Hall

Dissertation: Structure-Function Studies of the cAMP-Dependent Protein Kinase In Vitro and in Intact Cells , Gary Z. Morris

Dissertation: Modulation of TGFβ-Induced PAI -1 Expression by Changes in Actin Polymerization in Human Mesangial Cells , Keyur Patel

Dissertation: Cellular Mechanism of Arglabin-Dimethylaminohydrochloride Cytotoxicity , Xiaofei Qin

Dissertation: The Study of Nitric Oxide Synthase Expression, Function, and Regulation in the Renal Vasculature During Postnatal Renal Development , Brian Blake Ratliff

Dissertation: The Use of Proteomic Technologies to Identify Serum Glycoproteins for the Early Detection of Liver and Prostate Cancers , Elizabeth Ellen Schwegler

Dissertation: Diverse Effects of Nanosecond Pulsed Electric Fields on Mammalian Cells , Jody Anne White

Theses/Dissertations from 2005 2005

Dissertation: Mechanisms of Cell Death Initiated in Herpes Simplex Virus Thymidine Kinase Expressing Colon Tumor Cells Treated with Ganciclovir and UCN-01 , Christina Elizabeth Ahn

Dissertation: Regulation of SPARC Gene Expression by the Activator Protein 1 Transcription Factor , Joseph William Briggs

Dissertation: Defensin in the Ticks Dermacentor variabilis and Ixodes scapularis , Shane Michael Ceraul

Dissertation: Developing and Optimizing Conditions for Single Cell Genetic Analysis , Susan Adele Gitlin

Dissertation: Tumor Response TCF-4/β-Catenin Regulatory Elements for Enhancing Cancer Gene Therapies , Saurabh Kumar Gupta

Dissertation: The Antitumor Agent, Arglabin-DMA, Preferentially Induces Apoptosis in Human Colon Tumor Cells , Sung Wook Kwon

Theses/Dissertations from 2004 2004

Dissertation: The Ultrastructure of the Olfactory System in Two Species of Short-Tailed Shrews, Blarina brevicauda and Blarina carolinensis , Lisa Johnson Byrum

Theses/Dissertations from 2003 2003

Dissertation: Characterization of Mouse Prostate Tumor-Infiltrating Leukocytes , Daniel Alan Holterman

Dissertation: The Quantitative Assessment of Osteoinductivity of Human Demineralized Bone Matrix and cDNA Array Analysis of Osteogenic Differentiation in Human Periosteal Cells , Sittisak Honsawek

Dissertation: Embryo and Gamete Development Upon Exposure to CCA Components: CrO3, CuO, and AS2O5 , Nerbana Talaat-Elsebaei Mahmoud

Dissertation: K+-Induced Smooth Muscle Calcium Sensitization Requires RhoA Kinase (ROK) Translocation to Caveolae Which Is Inhibited in Non-Neuronal Cell Memory , Nicole Hairrell Urban

Dissertation: Hyaluronate Lyase Gene of Streptococcus pyogenes : Molecular Characterization and Regulation , Sheryl Lynne Walton

Theses/Dissertations from 2002 2002

Dissertation: Involvement of Platelet-Derived Growth Factor, PDGF Receptor Signaling, Focal Adhesion Kinase and SRC in Pressure-Induced Vascular Smooth Muscle Hypertrophy , Darian Clark Rice

Dissertation: Apoptosis Pathways: Presence and significance in Ejaculated Human Spermatozoa , Steven Lewis Taylor

Dissertation: Prostate Specific Membrane Antigen (PSMA): Immunoassay Development and Characterization of Transcriptional Regulation , Zhen Xiao

Theses/Dissertations from 2001 2001

Dissertation: Detection of Aneuploidy for Chromosomes 7 and 8 Using Fluorescence In Situ Hybridization in Patients with Aplastic Anemia and Sequencing of the Mitotic Checkpoint Gene hBUB1 , Laura Jane Aridgides

Dissertation: Characterization of Murine Cytomegalovirus m142 and m143 Essential Gene Products , Bridget Linette Dalton

Dissertation: Estrogen Regulation of the Pregnant Baboon Placental 11β-Hydroxysteroid Dehydrogenase (11β-HSD)-Catalyzed Metabolism of Cortisol and Cortisone and Its Effect on the Development of the Fetal Hypothalamic-Pituitary-Adrenal Axis , William Adair Davies

Dissertation: Regulation of the HCMV UL98 Promoter by Cooperation of the Cyclic AMP Response Element and Gamma Interferon Response Element , Tabmitha Patricia Young Jervey

Dissertation: Interactions Among Murine Cytomegalovirus US22 Family Gene Products That Influence Viral Pathogenesis , Zaruhi Karabekian

Dissertation: Characterization of the Biological Activities of Recombinant Fusion Protein Green Fluorescent Protein/Human Zona Pellucida Protein 3 (GFP/HZP3) , Zhiyong Lin

Dissertation: Characterization of the Human Cytomegalovirus UL75 Late Gene Promoter , Bernard J. P. McWatters

Theses/Dissertations from 2000 2000

Dissertation: Characterization of Human T-Cell Leukemia Virus 1 Reverse Transcriptase , Pinky Gundayao Agbuya

Dissertation: Mechanistic Characterization of the Mitochondrial Type I DNA Topoisomerase and a Study of Genes Containing Type I DNA Topoisomerase-Related Domains , Jaydee Dones Cabral

Dissertation: Role of Lipolysis and Lipogenesis in the Development of Diet-Induced Obesity , Michael John Davies

Dissertation: Transcriptional Regulation of Chicken Apolipoprotein A-I Gene Expression , Wen Lin Kumfert

Dissertation: Investigations on the Use of Ion Mobility Spectrometry for Clinical Chemistry Applications , Henri Parson Patten

Dissertation: Telomerase Activity in Human Preimplantation Embryos , Diane Lynne Wright

Dissertation: Human Gonadotropin-Releasing Hormone (hGnRH) Gene Expression and Hormone Regulation in Human Placental JEG-3 Cells , Heming Zheng

Theses/Dissertations from 1999 1999

Dissertation: Production of Copper-Complexing Ligands in Response to Elevated Concentrations of Copper in Marine Synechococcus spp. , Arunsri Chatkaeomorakot Brown

Dissertation: Construction of an Escherichia coli lac Repressor-Based System to Study Human Cytomegalovirus Gene Expression , Laura Fernanda Cageao-Luchetti

Dissertation: Tissue-Specific Expression and Steroid Hormone Regulation of Human Gonadotropin -Releasing Hormone (hGnRH) Gene in Placental Cells (JEG -3 cells) , Zhengguang Chen

Dissertation: Identification and Characterization of Determinants of Head and Neck Tumor Cell Invasion , Yangguan Wu

Theses/Dissertations from 1998 1998

Dissertation: Expression, Isolation and Purification of Human Zona Pellucida Protein 3 , Ting-Fung Chi

Dissertation: Characterization of the Biological Functions of Human Recombinant Zona Pellucida Protein 3 , Yu Wen Juan

Dissertation: Pressure-Induced Intracellular Signaling in Isolated Arteries , Victor A. Miriel

Dissertation: Leukemia Inhibitory Factor (LIF): Murine Preimplantation Embryo Development, Implantation Rates, and Skeletal Development , Michael Hayes Mitchell

Dissertation: The Role of Glycoconjugates in Mediating Human Fertilization and Induction of Fetomaternal Tolerance , Manish S. Patankar

Dissertation: Mouse Embryo Development in the Presence of Capsaicin , Carlos Santiago Villar-Gosalvez

Theses/Dissertations from 1997 1997

Dissertation: Differential Endometrial Responses of Primates vs Rodents: Screening for Antiproliferative Effects of Antiprogestins , David Williams Burleigh

Dissertation: Fluorescence in Situ Hybridization Analysis of Human Embryos Derived From in Vitro and in Vivo Matured Oocytes , Constance DeScisciolo

Dissertation: Choline Acetyltransferase and Carnitine Acetyltransferase Activity in Human Spermatozoa During Capacitation , Lisa A. Eccles

Dissertation: Abnormalities in Post-Translational Processing of Platelet Rap 1B in NIDDM: A Possible Cause of Platelet Hyperactivity and Cardiovascular Disease in Diabetes , Elizabeth Ann Hall

Dissertation: Interaction of ACTH and Estradiol in the Regulation of Growth, Differentiation, and Steroidogenic Maturation of the Baboon Fetal Adrenal Gland , Maria Gomez Leavitt

Dissertation: The Cellular and Molecular Dynamics of the Queuosine Modification in Transfer RNA: Definition, Modulation, Deficiencies and Effect of the Queuosine Modification System , Rana C. Morris

Dissertation: Characterization of the Fast Axonally Transported Proteins in the Rat Optic Pathway , Surafel Mulugeta

Dissertation: Arterial Wall Hypertrophy and PDGF-A Expression in One-Kidney, One-Clip Hypertension and Angiotensin II Infusion Are Mediated By Elevated Arterial Pressure , Sheri Blair Parker

Dissertation: Type II Estrogen Binding-Site Agonist: The Synthesis and Biological Evaluation of the Enantiomers of Methyl-Para-Hydroxyphenyllactate (MeHPLA) , Lester G. Pretlow

Dissertation: The Effects of Estrogen on Dorsal Root Ganglion Neurons , Sheila A. Scoville

Dissertation: Axotomy and Regeneration of the Rat Facial Nerve: A Histomorphometric Study of the Facial Nucleus, Nerve and Orbicularis Oculi Muscle in an Experimental Model of Facial Paralysis , Peter Konstantinos Thanos

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How to write a Doctoral Thesis

Prof. HR Ahmad, Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi, Pakistan. E-mail: [email protected]

Note: * Ahmad HR. In: Medical Writing. Eds. SA Jawaid, MH Jafary & SJ Zuberi. PMJA, 1997 Ed II: 133-142.

PATIENT care and teaching are rather well established components of our medical career. However, with the passage of time a third component has started to influence our medical culture, namely research. 1 - 4 How to accept this challenge is a question. 5 Indeed, teaching and research form a dialectic unit, meaning that teaching without a research component is like a soup without salt. It is a well-established fact that the research activity of an institution is directly proportional to the number of qualified and committed PhD candidates. An inspiring infrastructure, laboratory facilities and libraries are pre-requisites for a research culture to grow. 6 - 8 This forms the basis of a generation cycle for an institution, so that research activity and its culture continues to grow from one generation to the next. The main objective of doctoral work in biomedical sciences is to develop a galaxy of scientist physicians and surgeons possessing high degree of humility, selflessness and ethical superiority. Such a programme will add a scholastic dimension to the clinical faculty.

Education in how to write a doctoral thesis or dissertation should be a part of the postgraduate curriculum, parallel to the laboratory work and Journal Club activities during the PhD studies and/or residency levels. 9 , 10 The overall structure of a doctoral thesis is internationally standardized. However, it varies in style and quality, depending upon how original the work is, and how much the author has understood the work. Therefore a thorough discussion with supervisor, colleagues and assistance from other authors through correspondence can be useful sources for consultation.

The choice of a topic for a doctoral thesis is a crucial step. It should be determined by scanning the literature whether the topic is original or similar work has already been done even a hundred years ago. It is the responsibility of both the supervisor and the PhD candidate to sort out this problem by continuous use of internet and a library. 11 The work leading to the PhD degree can originate from research in following spheres: 12

• b) Methodology
• c) Diagnostic
• d) Therapeutic and Management
• e) Epidemiology

The availability of internationally standardized methods, as well as research committed supervisors can enable physicians and surgeons to do PhD work in both basic and clinical health sciences. The importance of research in basic health sciences cannot be overemphasized. It is rather the base of the applied sciences. There are many instances where the elucidation of a mechanism involved in a process awaits the development of an adequate methodology. 13 In such a scenario; a new method is like a new eye. Research activity in the field of (a) and (b) illuminates the research directions for (c) (d) and (e). It is worth noting that sometimes important basic questions can come from (e) and stimulate research activity in the domain of basic health sciences. 14 , 15

Types of Doctoral Thesis

TYPE-I: Book Form: a classical style. The blueprint of this form is shown in Table-I .

Type-I: The Classical Book Form

TYPE-II: Cumulative Doctoral thesis: A modem but quite useful practice.

INTRODUCTION

A book containing the pearls of a PhD work has standardized divisions and formats, where the number of pages should be weighted in terms of content rather than container. The book includes summary, introduction, materials and methods, results, discussion, conclusions, references and acknowledgements.

Two exercises are mandatory before starting a PhD programme:

• Literature survey using a regular library hours and internet surfing
• Familiarization with the hands-on-experience of methodology involved in the work
• The importance of a continuous literature survey using library, internet and direct correspondence with authors across the globe in the same field cannot be over-emphasized. The main goal of this exercise is to pinpoint the unresolved problem in the literature. An attempt to solve this problem now becomes the topic of the PhD thesis. All the relevant references should be collected, and carefully preserved in the form of a card system arranged alphabetically according to themes and authors. The introduction of the thesis should be styled like a review article with a critical analysis of the work of authors in the literature. The aims of the present PhD work can then also be addressed in the form of questions. The objectives would then deal with how to achieve the aims of the proposed study.

MATERIALS / SUBJECTS AND METHODS

Now comes the most crucial and functional part of the doctoral work, the materials/subjects and methods section. This part can be considered as the motor of the PhD work. The reliability, sensitivity and specificity of the motor must be checked before embarking on a long journey. Controlling the controls is the best guide for a precise and authentic work. Usually materials and methods contain components such as a description of the species involved, their number, age, weight and anthropometric parameters, types of surgical procedures and anesthesia if applied, and a detailed description of methodology. Continuous or point measurements should be thoroughly described. However, a dynamic method should always be preferred to static one.

The experimental protocol should be designed after a small pilot study, which is especially advisable in research on human subjects. A detailed and well-thought experimental protocol forms the basis of conditions under which the results would be obtained. Any deviation from the experimental protocol will affect the outcome, and the interpretation of results. It may be noted that great discoveries are usually accidental and without a protocol, based merely on careful observation! However, for the sake of a publication, a protocol has to be designed after the discovery. After having described the different phases of the experimental protocol with the help of a schematic diagram e.g., showing variables, time period and interventions, the selection of a statistical method should be discussed. Negative results should not be disregarded because they represent the boundary conditions of positive results. Sometimes the negative results are the real results.

It is usual practice that most PhD candidates start writing the methodological components first. This is followed by writing the results. The pre-requisites for writing results are that all figures, tables, schematic diagrams of methods and a working model should be ready. They should be designed in such a way that the information content of each figure should, when projected as a frame be visually clear to audience viewing it from a distance of about fifty feet. It is often observed that the presenters themselves have difficulty in deciphering a frame of the Power-Point being projected in a conference.

The results of a doctoral thesis should be treated like a bride. The flow of writing results becomes easier if all figures and tables are well prepared. This promotes the train of thoughts required to analyze the data in a quantitative fashion. The golden rule of writing results of a thesis is to describe what the figure shows. No explanation is required. One should avoid writing anything which is not there in a figure. Before writing one should observe each diagram for some time and make a list of observations in the form of key words. The more one has understood the information content of a figure; the better will be the fluency of writing. The interruption of the flow in writing most often indicates that an author has not understood the results. Discussion with colleagues or reference to the literature is the only remedy, and it functions sometimes like a caesarean procedure.

Statistical methods are good devices to test the degree of authenticity and precision of results if appropriately applied. The application of statistical technique in human studies poses difficulties because of large standard deviations. Outliers must be discussed, if they are excluded for the sake of statistical significance. Large standard deviations can be minimized by increasing the number of observations. If a regression analysis is not weighted, it gives faulty information. The correlation coefficient value can change from 0.7 to 0.4 if the regression analysis is weighted using Fisher’s test. The dissection of effect from artifact should be analysed in such a way that the signal to noise ratio of a parameter should be considered. A competent statistician should always be consulted in order to avoid the danger of distortion of results.

The legend of a figure should be well written. It contains a title, a brief description of variables and interventions, the main effect and a concluding remark conveying the original message. The writing of PhD work is further eased by a well maintained collection of data in the form of log book, original recordings, analyzed references with summaries and compiling the virgin data of the study on master plan sheet to understand the original signals before submitting to the procedures of statistics. The original data belong to the laboratory of an institution where it came into being and should be preserved for 5-7 years in the archive for the sake of brevity.

This is the liveliest part of a thesis. Its main goal is to defend the work by staging a constructive debate with the literature. The golden rule of this written debate should be that a rigid explanation looks backward and a design looks forward. The object is to derive a model out of a jig-saw puzzle of information. It should be designed in such a way that the results of the present study and those of authors from the literature can be better discussed and interpreted. Agreement and disagreement can be better resolved if one considers under what experimental conditions the results were obtained by the various authors. It means that the boundary conditions for each result should be carefully analyzed and compared.

The discussion can be divided into the following parts:

• criticism of material/subjects and methods
• a list of important observations of the present study
• interpretation and comparison of results of other authors using a literature table
• design of a model
• claim of an original research work
• The criticism of the methodological procedure enables a candidate to demonstrate how precisely the research work has been carried out. The interpretation of results depends critically on the strict experimental protocol and methods. For example, an epidemiological work is a study of a population. However, if the population sampling is done regularly at a specific location; the question arises as to how a result derived from a localized place can be applied to the whole population.
• After having discussed at length the strong and weak points of material/subjects and methods, one should list in a telegraphic design the most important observations of the present study. This may form a good agenda to initiate interpretation, argument, reasoning and comparison with results of other authors. The outcome of this constructive debate should permit the design of a working model in the form of a block diagram. All statements should be very carefully referenced. The ratio of agreement and disagreement should indicate the ability of the author to reconcile conflicting data in an objective and quantitative way. Attempts should be made to design a solution out of the given quantum of information. It is also well known that most of the processes of human physiology can only be understood if their time course is known. The dynamic aspect of interpretation of results is therefore more powerful and superior to the static one. 16 Therefore a continuous record of variables should be preferred and sought to reveal the secrets hidden in the kinetics.
• Finally, the discussion should conclude how far the study was successful in answering the questions being posed at the end of the introduction part. Usually a doctoral thesis raises more questions than it answers. In this way research does not come to a standstill and does become a life time engagement for a committed scientist. Also it is important to note that all scientific theses should be quantifiable and falsifiable, otherwise they lose the spirit and fragrance of a scientific research.
• The author’s claim of original work is finally decided by the critical review of his research work by the literature and the number of times being cited. It can be easily read by a high rate of a citation index of a publication and invitation. When a methodological research clicks, one becomes a star overnight.

Type-II: CUMULATIVE DOCTORAL THESES

Another way of writing a doctoral work is a cumulative type of thesis. 11 It consists of a few original publications in refereed journals of repute. It is supplemented by a concise summary about the research work. This type of thesis is usually practiced in Sweden, Germany and other countries. It has the advantage of being doubly refereed by the journals and the faculty of health sciences. Additionally, papers are published during a doctoral work. A declaration has to be given to the faculty of science about the sharing of research work in publications, provided there are co-authors. The weightage should be in favour of the PhD candidate, so that the thesis can ethically be better defended before the team of august research faculty.

ACKNOWLEDGEMENTS

A critical review of this manuscript by Dr. Roger Sutton, Dr. Khalid Khan, Dr. Bukhtiar Shah and Dr. Satwat Hashmi is gratefully acknowledged.

Dedicated to the memory of Mr. Azim Kidwai for his exemplary academic commitment and devotion to the science journalism in Pakistan.

Home > Communities > School of Medicine & Health Sciences > Department of Biomedical Sciences > BMS-GRAD

Biomedical Sciences Theses and Dissertations

Theses/dissertations from 2023 2023.

Understanding NANOG's Role During Cell Differentiation , Oluwatobiloba Samuel Aminu

The Interplay Between PARP-1 And Histone Modifications In Transcriptional Regulation During Development And Heat Shock Response , Gbolahan Gbenga Bamgbose

CCl2 Suppression In Lewis Lung Carcinoma Model Enhances Host Survival And Immune Response In The Tumor Microenvironment , Nivedita Biswas

Neuromodulatory Mechanisms Of Neuropeptides In The Amygdala , Cody Adam Boyle

The Effect Of Sterol Carrier Protein 2 Gene Ablation And Dietary Cholesterol On Brain And Liver Lipid Composition In Male And Female Mice , Madison Jochim

Staphylococcal Enterotoxin I Immunotherapy Combined With HLA-DQ8 Induces Tumoricidal Activity, With Low Superantigen Toxicity, Leading To Long-Term Survival And Tumor-Specific Memory Against Established B16-F10 Melanoma In Humanized HLA-DQ8 Transgenic Mice , Nathan Velaris

Theses/Dissertations from 2022 2022

Role Of Aurora Kinase A, Rab4a, And Endolysosomes In The Development Of Alzheimer’s Disease-Like Pathology , Zahra Afghah

The Discovery And Investigation Of Jig (CG14850): A Previously Uncharacterized Novel Drosophila Melanogaster Protein , Sayem Hoque Bhuiyan

Modulation Of Monoamine Transporters By Palmitoylation In Human Health And Disease , Christopher Ryan Brown

Effects Of Small Molecule FAK Activators On Gastrointestinal Mucosal Healing , Sema Oncel

The Effects Of The Alpha1a Adrenergic Receptor In Modulating Psychiatric Symptoms , Jason Power

RSV-Induced Actin Modulation: Contributes To Bronchial Wall Thickening; Does Not Induce Emt, And Is CDC42-Assisted , Sattya Narayan Talukdar

Translocation Of Yops By Yersinia Pestis Into Canine Cell Lines , Betsy Louise Young

Theses/Dissertations from 2021 2021

Using Machine Learning On Diverse Datasets To Predict Drug-Induced Liver Injury , Temidayo Adeluwa

Role Of Gravin/AKAP12 Variants In Regulating Endothelial Cell Behavior , Ashrifa Ali

Role Of Schlafen 12 In Lung Adenocarcinoma And Triple Negative Breast Cancer , Sarmad Al-Marsoummi

Transcriptomic Analysis Of Young Regenerating Magnocellular Neurons (MCNs) Vs Mature Non- Regenerating MCNs , Malak Alzidaneen

Effects Of HIV-1 Gp120 On Intracellular Levels Of Iron And Reactive Oxygen Species: Implications For Lysosomal Stress , Koffi L. Lakpa

The Effect Of Fatty Acid-Binding Protein 1 Gene Ablation On Brain And Liver Lipid Metabolism , Regan Clarice Lawrence

Endolysosome Involvement In The Protective Effects Of 17ơ-Estradiol Against HIV-1 Protein-Induced Neuronal Injury , Nicole Miller

Snail As A Dual DNA/RNA Binding Transcription Factor , Smruthi Rudraraju

Pathological Role Of Interferon (IFN)-Gamma During Influenza Pathogenesis , Taylor Marie Schmit

Theses/Dissertations from 2020 2020

Molecular Mechanisms Of Transcriptional Responses In Stress-Induced Human Cells , Sayantani Ghosh Dastidar

Characterizing Palmitoylation On The Sodium Hydrogen Exchanger Isoform 1 (NHE1) , Moriah Hovde

Interferon-γ Medaites Lung Damage Through The Hyper-Activation Of Ccr2+ Inflammatory Monocytes During Influenza Virus Infection , Mitchell Anthony Klomp

Contribution Of Intestinal Dysfunction To Alzheimer’s Disease Progression , Mona Sohrabi Thompson

Investigation Of The Neurological Manifestations Of Lyme Disease And The Impact Of Borrelia Burgdorferi On The Epigenetic Landscape Of Astrocytes , Derick Thompson

Theses/Dissertations from 2019 2019

Interplay Between Environmental Signals And Chromatin Remodeling During The Process Of Epithelial To Mesenchymal Transition (EMT) , Atrayee Bhattacharya

SPARC, A Matricellular Protein, In A Cell Culture Model Of Heavy Metal Cadmium Induced Bladder Urothelial Carcinoma , Emily Rae Biggane

Alpha1a-Adrenergic Receptor Modulation Of Epileptiform Activity And Seizures , Joseph Patrick Biggane

Endolysosome Dysfunction And Inter-Organellar Signalling: An 'Iron-Ic' Story , Peter Halcrow

Inflammation Is A Common Factor Between Central And Peripheral Neurodegeneration , Brett Anthony Mcgregor

Avian IgY As An Immunotherapy For Flaviviral Infections , Kyle O'donnell

Effects Of A Confidence-Based, Individualized Remediation Strategy On Student Learning And Final Grades In A Multi-Campus Human Anatomy Curriculum , Ethan Snow

Characterization Of Dopamine Transporter Amino Terminal Palmitoylation And Neurotoxic Substrate Activity , Daniel Jacob Stanislowski

Understanding the Molecular and Cellular Functions of Odd-Skipped Related 1 in Outflow Tract Development , Menglan Xiang

Theses/Dissertations from 2018 2018

The Involvement Of Polyol Pathway In Hypgerglycemia And Cadmium Toxicity In The Establishment Of Diabetic Neprhopathy , Bethany Anne Davis

Staphylococcal Enterotoxins G And I Elicit Long-Term Anti-Tumor Responses In Humanized HLA-DQ8αβ Transgenic Mice , Peter Knopick

Amyloid Precursor Protein And Insulin Homeostasis , Joshua Kulas

Trpc1-Mediated Ca2+ Entry Regulates Metabolism By Modulating Adipose Differentiation, Autophagy, And Adiponectin Secretion , Anne Schaar

The Effects Of 27-Hydroxycholesterol And Palmitic Acid On Parkinson's Disease-Like Pathology , Jared Schommer

Isolation And Characterization Of Stem Cell Population In Human Proximal Tubule Cells And The Effect Of Cadmium In The Isolated Proximal Tubule Stem/progenitor Cell Line. , Swojani Shrestha

Characterization Of Infectious Isolates Of Borrelia Burgdorferi In North Dakota, Bb0399 And Bbb28 In B. Burgdorferi, And Borrelia Miyamotoi In Vitro And In Vivo , Brandee Lynn Stone

The Role Of The Cholesterol Metabolite, 27-Hydroxycholesterol, In Colon Cancer Cells , Jessica A. Warns

Theses/Dissertations from 2017 2017

Characterization Of The Immune Stimulating Properties Of Type III Secretion System Needle Protein Bscf From Bordetella Pertussis: Towards The Development Of A New Acellular Pertussis Vaccine , Travis Douglas Alvine

Acetate Supplementation Reduces Disease Progression, Alters Cns And Myelin Lipid Content, And Influences Cns And Myelin Protein Content In Mice Subjected To Experimental Autoimmune Encephalomyelitis , Amber C. Chevalier

Mechanisms Of Dopaminergic, Histaminergic, And Glutamatergic Neuromodulation Within The Medial Entorhinal Cortex , Nicholas Ian Cilz

Mechanistic Insights Into Neutrophil Turnover During Gram-Negative Pneumonic Sepsis , Christopher Jondle

Amphetamine Exposure During Embryogenesis Leads To Long-Term And Transgenerational Increase In Behavioral Response And Decrease In Dopamine Uptake , Talus J. Mccowan

Immune Regulatory Mechanism And Myeloid Cells Functions In Brain Parasite Infection , Fredice Quenum Zangbede

Molecular Mechanisms Regulating Rna Polymerase Ii Pausing During Gene Activation , Ann Sanoji Samarakkody

The Role Of Α-Synuclein In Brain Lipid Metabolism And Inflammation , Drew R. Seeger

Epigenetic Remodeling As A Mediator Of Environmental Toxicant Exposure In The Brain , Christopher David Walden

Theses/Dissertations from 2016 2016

Chronic Amphetamine Exposure Causes Long Term Effects On Dopamine Uptake In Cultured Cells , Nafisa Ferdous

Characterization Of Two Surface Proteins From The Lyme Spirochete And Their Roles During Mammalian Infection , Robert Anthony Gaultney

Using Simian Virus 40 As A Model To Determine The Effects Of Replication And Transcription On Histone Methylation , Les Kallestad

Understanding Addiction, Depression, And Autism Spectrum Disorder Through Structure-Function Analyses Of The Dopamine And Serotonin Transporters , Danielle Krout

Gata4 Interacts With Hedgehog Signaling Pathway In Regulating Outflow Tract Development , Jielin Liu

Role Of The Cholesterol Metabolite 27-Hydroxycholesterol In Breast And Prostate Cancer , Shaneabbas S. Raza

The Impact Of Anterior Gradient 2 (AGR2) Expression In Models Of Arsenite And Cadmium Induced Breast And Bladder Cancers , Jamie Lynn Van Gieson

Theses/Dissertations from 2015 2015

The Growth And Metabolic Effects Of Pseudouridine Synthase Gene Deletion On Escherichia Coli Strain Bl21 , Lisa Marie Burnette

Alpha1a Adrenergic Receptor Influences On Adult Neurogenesis, Cell Fate, Mood, Learning, Memory, Lifespan, And Cancer Incidence , Katie Collette

Understanding The Structure-Function Relationships Between Monoamine Neurotransmitter Transporters And Their Cognate Ions And Ligands , Bruce Felts

Corticotropin-Releasing Factor Facilitates Epileptiform–activity In The Entorhinal Cortex Via CRF2 Signaling Mechanisms , Lalitha Kurada

Regulation Of Vectorial Active Transport In Human Proximal Tubule Cells By MT-3: The Role Of The C-Terminal Domain On E-And N-Cadherin Expression And The Confirmation Of Protein-Protein Interactions , Andrea Marie Nore

The N-Terminus Of Type III Secretion Needle Protein YscF From Yersinia Pestis Functions To Modulate Innate Immune Responses , Patrick Osei-Owusu

Characterization Of Dopamine Transporter Palmitoylation , Danielle Elizabeth Rastedt

N-Cadherin Expression And EMT Progression In Arsenic- And Cadmium-Transformed Urotsa , Elizabeth Sandquist

Innate Immune Response To Yersinia Pestis , Sanghita Sarkar

Dopamine Transporter Phosphorylation, Palmitoylation And Membrane Localization And Mobility In Health And Disease , Madhur Shetty

Role Of Lectins Receptors In Development Of Sepsis During Pulmonary Bacterial Infection , Anthony Lee Steichen

The Unique N- And C-Terminal Domains Of Metallothionein-3 Influence The Growth And Differentiation Of Breast Cancer Cells , Brent Jeffrey Voels

The Role Of Atg7 In The Host Defense Against Bacterial Infection , Yan Ye

Theses/Dissertations from 2014 2014

The Interplay Between Aging, Growth Hormone, The Methionine Pathway, And Epigenetic Methylation Marks And Mechanisms , Vanessa Louise Armstrong

Regulation Of Proline-Directed Phosphorylation Site, Threonine 53 On Dopamine Transporter , Sathyavathi Challasivakanaka

Role Of BipA As A Modulator Of Gene Expression And Ribosome Assembly In Escherichia Coli , Promisree Choudhury

Attachment Sites Of Irreversible Cocaine Analogs On The Dopamine Transporter , Rejwi Acharya Dahal

Goose-Derived Igy: A Potential Therapeutic Antibody For The Treatment Of Infectious Disease , Ashley Louisa Fink

Role Of The α1A-Adrenergic Receptor In Synaptic Plasticity, Cognition & Neurogenesis , Brianna Lynn Goldenstein

Therapeutic IgY: Safe, Diverse, And Effective For Use Against Viral Targets , Nicole Noel Haese

Theses/Dissertations from 2013 2013

Acetate Increases Brain Purine Metabolism And Glial Cell Culture Fatty Acid Content: Studies Investigating Glyceryl Triacetate's Therapeutic Mechanism Of Action , Dhaval Paresh Bhatt

Epigenetic Patterns: Process-Driven Or Sequence-Driven? , Amanda Gefroh

Inhibition Of The Ysc Type III Secretion System Of Yersinia Pestis By Compound D And Interaction Of Type III Secretion System Needle Proteins With Host Receptors , Danielle L. Jessen

A Mass Spectrometry-Based Method For Quantification Of Human Metallothionein Isoforms And Usefulness In Biomarker Detection Of Cancers And Metal Toxicity , Aaron Andrew Mehus

Role Of The Alzheimer's Amyloid Precursor Protein In High Fat Diet Induced Obesity And Regulating Macrophage Phenotype , Kendra L. Puig

Theses/Dissertations from 2012 2012

Ciliary neurotrophic factor signaling in the magnocellular neurosecretory system : mechanisms of neuronal survival and sprouting , Jason Michael Askvig

Analysis Of The Role Of Amphetamine In The Induction Of Changes In Histone Modifications Of Dopaminergic Pathway Genes , Amritendu Chakraborty

Cholesterol Dyshomeostasis And Age Related Macular Degeneration , Bhanu Chandar Dasari

The Role Of Endolysosomes In Models Of Neurodegenerative Disorders And In Regulating Levels Of Intracellular Calcium , Liang Hui

Analysis Of Yscf And Associated Homologs And The Presence Of An Inflammatory Molecular Pattern , William Andrew Roughead

Neuroglial Mechanisms Involved In The Anti-Inflammatory Effect Of Acetate Supplementation , Mahmoud Lotfy Soliman

Induced Gene Expression In Bladder Cancer: Kindlin-2 And Metallothionein-1x , Sherine Talaat

Roles of CCAAT/enhancer-binding protein [beta] and [-delta] in immunoglobulin G immune complex-induced Inflammation , Chunguang Yan

Theses/Dissertations from 1994 1994

The Effect of an Anaerobic Training Program Utilizing A Skating Treadmill on Anaerobic Performance, Lactate, and Other Metabolic Parameters , Trini T. Vargas

Theses/Dissertations from 1991 1991

Measurement of Ascorbic Acid and Dehydroascorbic Acid in Mammalian Tissues using HPLC with Electrochemical Detection , Debra A. Fry

Theses/Dissertations from 1988 1988

Lysosomal Enzymes in Undifferentiated and Differentiated HL-60 Cells , Julie J. Ackerman

A Study of the Effects of Polyethylene Glycol on Interactions Between Glycolytic Enzymes and F-Actin, and Among Glycolytic Enzymes , Julie L. Walsh

Theses/Dissertations from 1985 1985

Surface Coat Material Associated with the Developing Otic Vesicle , Allan R. Sinning

Theses/Dissertations from 1983 1983

Release of Histone Lysine Methyltransferases from Rat Brain Chromatin by Nuclease Digestion , Dale V. Onisk

Theses/Dissertations from 1980 1980

Carboxyl Methylation of Non-Histone Chromosomal Proteins , Douglas P. Quick

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Major subjects

Biochemistry.

Do histone modifications control gene expression?

Does endotoxin cause or contribute to neurodegenerative diseases?

Molecular interactions of drugs with the allosteric sites of vertebrate Cys-loop receptors

Why do bacteria carry toxin-antitoxin systems?

Aneuploidy in cancer: lessons so far

Big data in genomics and healthcare and how it has defined cancer diagnosis and treatment

Modelling in Biology: accurate descriptions of our pathetic thinking or pathetic descriptions of the real world?

Trace the economic and biological causes of the current antibiotic resistance crisis. Is there a solution and, if so, does it lie in the hands of patients, clinicians, regulators or researchers?

Transposable elements – a powerful force driving evolution

Can the gut microbiota influence host appetite? Implications for the aetiology of obesity

Can vaccine innovation solve the last mile problem for vaccines in low-resource settings

Eradication of Polio: Past Challenges and Future Prospects

Is the age of antibiotics over?

Microbiome regulation of the gut-brain axis: implications for anxiety and depression

On the origin of the bacterial flagellum: an example of irreducible complexity?

Recent advances in the blockade of immune checkpoints in cancer immunotherapy

What are the major causes of delay in response to emerging disease outbreaks: the case of the 2014-2016 Ebola outbreak in West Africa

Pharmacology

Cystic-fibrosis related diabetes

How do SNAREs mediate membrane fusion?

Is CRISPR ready for the clinic?

Phantom pain: a ghost in the machine or a biological basis?

Plant-derived polysaccharides - sweet medicine of tomorrow?

Why are opioids problematic analgesics?

Plant Sciences

"Scrambled Genomes": examining the methodology and goals of the Sc2.0 synthetic genome project

Engineering C4 Rice: Molecular Targets and Progress so far

Is Trehalose-6-phosphate a central regulator of plant carbon partitioning?

Sucrose signalling and its role in plant development

Who needs cells anyway?

Is visual adaptation diminished in autism spectrum disorders?

Memory reconsolidation blockade: a novel treatment for Post-Traumatic Stress Disorder

Parental influence on child language development: does gender matter?

Sleep disorders as model for Consciousness Research: a cognitive framework for parasomnias

The role of genetics in the transgenerational transmission of memories

The role of insulin in cognitive decline in the elderly

Physiology, Development and Neuroscience

Adaptations of cancer cells for metastasis to the brain

How and why is the infant gut microbiota affected by caesarean section? The crying need for well-designed research

How do astrocytes support and modulate neuronal function? Exploring neurovascular coupling, neurometabolic coupling, and gliotransmission

The missing nuances of science and society: How popular science is shaping policy and understanding

The role of operant conditioning in spinal cord plasticity and its potential therapeutic implications for spinal cord injury

The significance of proinflammatory mediators in disrupting HRV: a link to cardiovascular morbidity in schizophrenia?

Psychology, Neuroscience and Behaviour

Prenatal stress: relevance to major depressive disorder

Promises and limitations of a combinatorial approach to spinal cord injury

Social neurons? A critical examination of how individual neurons might implement primate social cognition

The bidirectional relationship between the hippocampus and metabolic syndrome

The Cognitive and Neurobiological Benefits of an Imperfect Memory

Why are drug seeking habits maladaptive?

How have homosexual mating preferences evolved in males and females?

How relevant is the Drosophila segmentation paradigm to the study of segmentation in other arthropods and other animals?

Mechanisms of mass extinction

Migration of Homo erectus out of Africa

The meaning of alarm calls: honesty and deception

Wolves verses Eurasian Lynx as candidates for large predator reintroduction in mainland Britain - which may be the most suitable and why?

Minor subjects

Conservation science.

Causes and remedies for the decline in red squirrel numbers in Britain

How do deer impact forest organisms in UK lowland woodland?

Reintroduction and translocation as conservation tools for rhinos

Translocation as a tool for tiger ( Panthera tigris ) conservation: problems and potential solutions

With respect to myxomatosis and RHD virus how have rabbit populations co-evolved with the viruses and how may rabbit populations be affected in the future?

Development and Psychopathology

To what extent have biasing in screening and diagnosis contributed to the sex ratios observed in autism?

Health, Medicine and Society

Medicalisation and violence against women: implications for the medical encounter

Human Ecology and Behaviour

The use of wood in prehistory

Neural Degeneration and Regeneration

Progress towards establishing lead times of biomarkers for early diagnosis of idiopathic Parkinson's disease

The Pharmacological Targeting of the Amyloid-beta pathway in Alzheimer's: issues and prospects

Philosophy and Ethics of Medicine

Dementia: how changing perspectives affect clinical decision making

Should the MMR vaccine be mandatory? The problem of herd immunity threshold

Psychology and Social Issues

Reducing Extremist Violence by increasing Integrative Complexity - why understanding the role of emotion is central to success

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Home > USC Columbia > Engineering and Computing, College of > Biomedical Engineering > Biomedical Engineering Theses and Dissertations

Biomedical Engineering Theses and Dissertations

Theses/dissertations from 2023 2023.

Laboratory Management Models in Core Facilities , Karmen Michael Owen

Detecting Physiological Concentrations of Alzheimer’s Associated Amyloid-β Protein Utilizing a Cell-Based Response , Brittany Elizabeth Watson

Volume Change Measurements of Cancer Cells in a Microfluidics Platform , Yukuan Yu

Theses/Dissertations from 2022 2022

Investigating the Impact of Endothelial Dysfunction and Aging On Vascular Remodeling Using Mouse Models , Liya Du

Histomechanical Compatibility of Coronary Artery Bypass Grafts , Colton J. Kostelnik

The Effect of Pulsed Field DC Electrophoresis and Field Amplified Sample Stacking on the Microchip Electrophoretic Separation of Organic Dyes , Travis Geoffrey Stewart

Long Non-coding RNA PVT1 – An Exploratory Study in Ovarian and Endometrial Cancer , Kevin Tabury

Interrogating the Role of ING4 in Hematopoietic Stem Cells and Cancer , Zanshé Thompson

Theses/Dissertations from 2021 2021

An in Vitro Approach To Vascular Therapeutic Testing , Shahd Ali Hasanain

Age and Sex Dependency of Thoracic Aortic Aneurysm Progression in a Mouse Model of Marfan Syndrome , Nazli Gharraee

Impaired Metabolic Flexibility in a Mouse Model Of Leigh Syndrome , Richard Sterling McCain Jr

Vascular Endothelial Dysfunction and Effects on Arterial Wall Microstructure , Jeffrey Thomas Rodgers

The Immune Modulatory Role of Endocannabinoid Anandamide to Suppress Inflammation Through Regulation of Microrna and Microbiome , Muthanna Ali Sultan

Theses/Dissertations from 2020 2020

Advanced Geometric Analyses in Vascular Disease and Interventions , Dara Ahmadi Azar

Nitric Oxide Expression With Age and Diet in the Arterial Wall of Apoe Knockout Mice , Kara Cooper

cis -Resveratrol Upregulates Tyrosyl-tRNA Synthetase and Inhibits the Proliferation of Select Breast Cancer Cell Lines , Marion Cone Hope III

Using Human Granulosa Cells to Select the Most Competent Embryos for Uterine Transfer in in Vitro Fertilization Cycles , Richard John Kordus

Effect of Cannabinoid Treatment on Immune Cell Functions During Acute Lung Injury , Amira Kamil Mohammed

Theses/Dissertations from 2019 2019

Beneficial Effects of Resveratrol Against Colitis and Colorectal Cancer Mediated by the Host Microbiome, Epigenome, and Immune Response , Haider Rasheed Daham Alrafas

Three-Dimensional Plasma Cell Survival Microniche in Multiple Myeloma , Katrina A. Harmon

Adipose Tissue Engineering: A Therapeutic Strategy for the Treatment of Obesity and Glucose Intolerance , Michael A. Hendley

Role of P-Glycoprotein in Alzheimer’s Disease for Enhanced Brain Elimination of Amyloid-β , Hope Holt

Three-Dimensional Collagen Tubes for In Vitro Modeling , Rebecca Jones

Experimental Methods and Techniques for Improved Biomechanical Characterization of Diverse Murine Aortopathies , Brooks Alexander Lane

Experimental Study of Free-Solution Separation Under Pulsed Electrophoresis in Microchip , Xin Liu

Biophysical Analyses of Left Ventricular Remodeling Secondary to Myocardial Infarction and Left Ventricular Pressure Overload , William Manuel Torres

RAGE Expression and Inflammation in Alzheimer’s Disease: in Vitro Model Development and Investigation of a Potential Peptoid Inhibitor , Lauren Michell Wolf

Theses/Dissertations from 2018 2018

Identification of the Mechanisms Through Which Botanicals Attenuate Pathogenesis of Human Diseases , Esraah Alharris

A Comprehensive Reengineering Of The Hospital Emergency Triage System , Nicholas D. Boltin

Matrix Stiffness Modulates Mesenchymal Stem Cell Sensitivity to Geometric Asymmetry Signals , Maria Eugenia Piroli

Association Between Mechanics And Biology In Vascular Graft Remodeling , David Andrew Prim

Modulation Of Amyloid-β Aggregation Via Small Molecules And Glycine Zipper Alterations , Steven Zebulon Vance

Theses/Dissertations from 2017 2017

Atherosclerotic Plaque Adhesion Strength and its role in Plaque Rupture , Bilal Merei

Far-Field Optical Microscopy Based on Stimulated Emission Depletion , Yunxia Wang

Theses/Dissertations from 2016 2016

A Theoretical Study of Polymer based Drug Delivery Systems , Ebtisam Abdullatif Aldaais

Automated Image Analysis And Spatial Computational Modeling Of NF-kB In Cerebrovascular Endothelial Cells , Kasey Catalfomo

Therapeutic Potential Of Catechins And Derivatives For The Prevention Of Alzheimer’s Disease , Shelby Elaine Chastain

A Mechanical Approach to the Characterization of Material Failure of Atherosclerotic Lesions , Lindsey A. Davis

Enabling Studies to Optimize Biomaterials for the Treatment of Myocardial Infarction , Eva Adriana Romito

Theses/Dissertations from 2015 2015

Effects of Cell Adhesion Peptides, pH, and Matrix Shape on Maintenance of Breast Cancer Stem Cells in an Engineered Hydrogel Matrix , Leily Daneshian

Design and Development of a Ventilation Chamber for Testing Efficacy of Tracheal Stents , Caroline N. Horton

Material Considerations for Development of 3D Printed Bronchial and Tracheal Stents , Nidah M. Hussain

Theses/Dissertations from 2014 2014

Isolation of Natural Nrf2 Activators from American Ginseng , Akrm Abdalrahman

Genes Mediating Cardiac Remodeling During Pregnancy and the Early Post-Partum-Period in Mice , Esam Aljrbi

A Three-Dimensional in Vitromodel of Atherogenesis , Pin Hsuan Chang

Identifying Performance Criteria of Fully Bioresorbable Scaffolds for Endovascular Applications , Jahid Ferdous

Novel Conditioning Protocols Focusing on Oxygen Manipulation to Enhance Stem Cell Transplantation , Brandon William Hanna

Developing a Bioreactor for Biaxial Mechanical Testing and Conditioning of Vascular Tissue , Steve Marcous

Experimental and Theoretical Studies of Native and Engineered Vascular Tissue Mechanics , Boran Zhou

Theses/Dissertations from 2013 2013

Toward Directing Cell Fate: Carbon Nanotubes As Modulators of Extracellular and Transporters of Intracellular Cues , Qingsu Cheng

Biomechanics of Porcine Renal Artery and the Development of A Replacment Vessel , Mohamed Gabr

Osteon-Mimetic Nanocomposite Materials For Bone Regeneration , Ozan Karaman

Microencapsulation of a Connexin-43 Mimetic Peptide as a Novel Wound Healing Agent in an Ocular Injury Model , Keith Brian Moore

Gold Nanoparticles and Peptoids as Novel Inhibitors of Amyloid Beta Aggregation in Alzheimer's Disease , Kelly Ann Moore

Effect of Physiological Oxygen Levels On Osteogenic Differentiation of Adipose-Derived Stem Cells , Suchit Sahai

Investigation of START Domain Proteins in Human Luteinized Cells and COS-1 Cells , Bo Shi

Characterizing Hypoxia and Its Behavioral Effects In 3-Dimensional Cell Aggregates , Matthew Lorincz Skiles

The Effect of αCT-1 Peptide on Bone Marrow Stromal Cells Following Injury , Adam Clay Vandergriff

Theses/Dissertations from 2012 2012

Flow-Induced Forces Regulate the Development of Cardiac Valves , Stefanie Vawn Biechler

Stimulated Emission Depletion (STED) Microscopy and Pacific Orange Dye Optimization For H9C2 Cox-1 Imaging Via Indirect Immunocytochemistry , John Wesley Merriman

Vasculogenic Scaffolds: How Cell-Cell and Cell-Matrix Interactions Regulate Vascular Differentiation and Morphogenesis , Samantha Jo Stinson

A Novel Quantitative Mechanical Test of Atherosclerotic Plaque Stability , Ying Wang

Theses/Dissertations from 2011 2011

Synthesis and Characterization of Thermally Responsive Nanocapsules Surface Decorated With Folic Acid For Targeted Drug Delivery and Cancer Destruction , Kyle Bradley Gilstrap

Study of Polyphenols and Naphthalimide Analogs As Inhibitors of Amyloid- β Protein Aggregation In Alzheimer'S Disease , Chen Suo

Development and Characterization of Micro/Nano Scale Biomaterials For Biomedical Applications , WUJIE ZHANG

Theses/Dissertations from 2010 2010

Study of Structural and Physical Properties of Small Molecule and Nanoparticle Inhibitors of Amyloid-B Protein Fibril Formation In Alzheimer'S Disease , Deborah Soto-Ortega

Theses/Dissertations from 2009 2009

A Novel Technique for Fabricating Aligned Nanofibers by Using Solution Electrospinning , Ozan Karaman

Synthesis and Characterization of Injectable Star-shaped Poly(Lactide-co-Glycolide-co-Acrylate) Macromers , Jianping Wu

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Biomedical Research Paper Topics

This page offers students an extensive list of biomedical research paper topics , expert advice on how to choose these topics, and guidance on how to write a compelling biomedical research paper. The guide also introduces the services of iResearchNet, an academic assistance company that caters to the unique needs of each student. Offering expert writers, custom-written works, and a host of other features, iResearchNet provides the tools and support necessary for students to excel in their biomedical research papers.

100 Biomedical Research Paper Topics

Biomedical research is a vibrant field, with an extensive range of topics drawn from various sub-disciplines. It encompasses the study of biological processes, clinical medicine, and even technology and engineering applied to the domain of healthcare. Given the sheer breadth of this field, choosing a specific topic can sometimes be overwhelming. To help you navigate this rich landscape, here is a list of biomedical research paper topics, divided into ten categories, each with ten specific topics.

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1. Genetics and Genomics

• Role of genetics in rare diseases
• Advances in gene editing: CRISPR technology
• Human genome project: findings and implications
• Genetic basis of cancer
• Personalized medicine through genomics
• Epigenetic modifications and disease progression
• Genomic data privacy and ethical implications
• Role of genetics in mental health disorders
• Prenatal genetic screening and ethical considerations
• Gene therapy in rare genetic disorders

2. Bioengineering and Biotechnology

• Tissue engineering in regenerative medicine
• Bioprinting of organs: possibilities and challenges
• Role of nanotechnology in targeted drug delivery
• Biosensors in disease diagnosis
• Bioinformatics in drug discovery
• Development and application of biomaterials
• Bioremediation and environmental cleanup
• Biotechnology in agriculture and food production
• Therapeutic applications of stem cells
• Role of biotechnology in pandemic preparedness

3. Neuroscience and Neurology

• Pathophysiology of Alzheimer’s disease
• Advances in Parkinson’s disease research
• Role of neuroimaging in mental health diagnosis
• Understanding the brain-gut axis
• Neurobiology of addiction
• Role of neuroplasticity in recovery from brain injury
• Sleep disorders and cognitive function
• Brain-computer interfaces: possibilities and ethical issues
• Neural correlates of consciousness
• Epigenetic influence on neurodevelopmental disorders

4. Immunology

• Immune response to COVID-19
• Role of immunotherapy in cancer treatment
• Autoimmune diseases: causes and treatments
• Vaccination and herd immunity
• The hygiene hypothesis and rising allergy prevalence
• Role of gut microbiota in immune function
• Immunosenescence and age-related diseases
• Role of inflammation in chronic diseases
• Advances in HIV/AIDS research
• Immunology of transplantation

5. Cardiovascular Research

• Advances in understanding and treating heart failure
• Role of lifestyle factors in cardiovascular disease
• Cardiovascular disease in women
• Hypertension: causes and treatments
• Pathophysiology of atherosclerosis
• Role of inflammation in heart disease
• Novel biomarkers for cardiovascular disease
• Personalized medicine in cardiology
• Advances in cardiac surgery
• Pediatric cardiovascular diseases

6. Infectious Diseases

• Emerging and re-emerging infectious diseases
• Role of antiviral drugs in managing viral diseases
• Antibiotic resistance: causes and solutions
• Zoonotic diseases and public health
• Role of vaccination in preventing infectious diseases
• Infectious diseases in immunocompromised individuals
• Role of genomic sequencing in tracking disease outbreaks
• HIV/AIDS: prevention and treatment
• Advances in malaria research
• Tuberculosis: challenges in prevention and treatment

7. Aging Research

• Biological mechanisms of aging
• Impact of lifestyle on healthy aging
• Age-related macular degeneration
• Role of genetics in longevity
• Aging and cognitive decline
• Social aspects of aging
• Advances in geriatric medicine
• Aging and the immune system
• Role of physical activity in aging
• Aging and mental health

8. Endocrinology

• Advances in diabetes research
• Obesity: causes and health implications
• Thyroid disorders: causes and treatments
• Role of hormones in mental health
• Endocrine disruptors and human health
• Role of insulin in metabolic syndrome
• Advances in treatment of endocrine disorders
• Hormones and cardiovascular health
• Reproductive endocrinology
• Role of endocrinology in aging

9. Mental Health Research

• Advances in understanding and treating depression
• Impact of stress on mental health
• Advances in understanding and treating schizophrenia
• Child and adolescent mental health
• Mental health in the elderly
• Impact of social media on mental health
• Suicide prevention and mental health services
• Role of psychotherapy in mental health
• Mental health disparities

10. Oncology

• Advances in cancer immunotherapy
• Role of genomics in cancer diagnosis and treatment
• Lifestyle factors and cancer risk
• Early detection and prevention of cancer
• Advances in targeted cancer therapies
• Role of radiation therapy in cancer treatment
• Cancer disparities and social determinants of health
• Pediatric oncology: challenges and advances
• Role of stem cells in cancer
• Cancer survivorship and quality of life

These biomedical research paper topics represent a wide array of studies within the field of biomedical research, providing a robust platform to delve into the intricacies of human health and disease. Each topic offers a unique opportunity to explore the remarkable advancements in biomedical research, contributing to the ongoing quest to enhance human health and wellbeing.

Choosing Biomedical Research Paper Topics

The selection of a suitable topic for your biomedical research paper is a critical initial step that will largely influence the course of your study. The right topic will not only engage your interest but will also be robust enough to contribute to the existing body of knowledge. Here are ten tips to guide you in choosing the best topic for your biomedical research paper.

• Relevance to Your Coursework and Interests: Your topic should align with the courses you have taken or are currently enrolled in. Moreover, a topic that piques your interest will motivate you to delve deeper into research, resulting in a richer, more nuanced paper.
• Feasibility: Consider the practicality of your proposed research. Do you have access to the necessary resources, including the literature, laboratories, or databases needed for your study? Ensure that your topic is one that you can manage given your resources and time constraints.
• Novelty and Originality: While it is essential to ensure your topic aligns with your coursework and is feasible, strive to select a topic that brings a new perspective or fresh insight to your field. Originality enhances the contribution of your research to the broader academic community.
• Scope: A well-defined topic helps maintain a clear focus during your research. Avoid choosing a topic too broad that it becomes unmanageable, or so narrow that it lacks depth. Balancing the scope of your research is key to a successful paper.
• Future Career Goals: Consider how your chosen topic could align with or benefit your future career goals. A topic related to your future interests can provide an early start to your career, showcasing your knowledge in that particular field.
• Available Supervision and Mentoring: If you’re in a setting where you have a mentor or supervisor, choose a topic that fits within their area of expertise. This choice will ensure you have the best possible guidance during your research process.
• Ethical Considerations: Some topics may involve ethical considerations, particularly those involving human subjects, animals, or sensitive data. Make sure your topic is ethically sound and you’re prepared to address any related ethical considerations.
• Potential Impact: Consider the potential impact of your research on the field of biomedical science. The best research often addresses a gap in the current knowledge or has the potential to bring about change in healthcare practices or policies.
• Literature Gap: Literature review can help identify gaps in the existing body of knowledge. Choosing a topic that fills in these gaps can make your research more valuable and unique.
• Flexibility: While it’s essential to start with a clear topic, remain open to slight shifts or changes as your research unfolds. Your research might reveal a different angle or a more exciting question within your chosen field, so stay flexible.

Remember, choosing a topic should be an iterative process, and your initial ideas will likely evolve as you conduct a preliminary literature review and discuss your thoughts with your mentors or peers. The ultimate goal is to choose a topic that you are passionate about, as this passion will drive your work and make the research process more enjoyable and fulfilling.

How to Write a Biomedical Research Paper

Writing a biomedical research paper can be a daunting task. However, with careful planning and strategic execution, the process can be more manageable and rewarding. Below are ten tips to help guide you through the process of writing a biomedical research paper.

• Understand Your Assignment: Before you begin your research or writing, make sure you understand the requirements of your assignment. Know the expected length, due date, formatting style, and any specific sections or components you need to include.
• Thorough Literature Review: A comprehensive literature review allows you to understand the current knowledge in your research area and identify gaps where your research can contribute. It will help you shape your research question and place your work in context.
• Clearly Define Your Research Question: A well-defined research question guides your research and keeps your writing focused. It should be clear, specific, and concise, serving as the backbone of your study.
• Prepare a Detailed Outline: An outline helps organize your thoughts and create a roadmap for your paper. It should include all the sections of your research paper, such as the introduction, methods, results, discussion, and conclusion.
• Follow the IMRaD Structure: Most biomedical research papers follow the IMRaD format—Introduction, Methods, Results, and Discussion. This structure facilitates the orderly and logical presentation of your research.
• Use Clear and Concise Language: Biomedical research papers should be written in a clear and concise manner to ensure the reader understands the research’s purpose, methods, and findings. Avoid unnecessary jargon and ensure that complex ideas are explained clearly.
• Proper Citation and Reference: Always properly cite the sources of information you use in your paper. This not only provides credit where it’s due but also allows your readers to follow your line of research. Be sure to follow the citation style specified in your assignment.
• Discuss the Implications: In your discussion, go beyond simply restating your findings. Discuss the implications of your results, how they relate to previous research, and how they contribute to the existing knowledge in the field.
• Proofread and Edit: Never underestimate the importance of proofreading and editing. Checking for grammatical errors, punctuation mistakes, and clarity of language can enhance the readability of your paper.
• Seek Feedback Before Final Submission: Before submitting your paper, seek feedback from peers, mentors, or supervisors. Fresh eyes can often spot unclear sections or errors that you may have missed.

Writing a biomedical research paper is a significant academic endeavor, but remember that every researcher started where you are right now. It’s a process that requires time, effort, and patience. Remember, the ultimate goal is not just to get a good grade but also to contribute to the vast body of biomedical knowledge.

iResearchNet’s Custom Writing Services

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• Expert Degree-Holding Writers: iResearchNet takes pride in our team of knowledgeable and experienced writers who hold advanced degrees in diverse fields. These writers are not only academic experts but are also keenly in tune with the complex landscape of biomedical research. This breadth and depth of expertise ensure that your paper benefits from a thorough understanding of the topic, resulting in a well-informed, academically credible document.
• Custom Written Works: We appreciate the unique academic goals and distinct requirements of each student. That’s why iResearchNet specializes in providing custom-written papers. Our aim is to capture your individual academic voice and perspective, blending it with our professional acumen to create a paper that reflects your specific academic needs and aspirations.
• In-Depth Research: Every paper that we produce is founded on the bedrock of extensive and in-depth research. Our writers are committed to exploring a wide range of credible and reputable sources to enrich your paper with diverse viewpoints and comprehensive information. This dedication to rigorous research ensures that your paper is not only thoroughly informed but also accurately referenced, adding to its academic integrity.
• Custom Formatting: Academic institutions often require different formatting styles. Be it APA, MLA, Chicago/Turabian, or Harvard, our writers are adept at all these academic formatting styles. We strive to adhere strictly to your specified formatting style, contributing to the polished and professional presentation of your paper.
• Top Quality: Quality is the cornerstone of our services at iResearchNet. We believe that each paper we craft should demonstrate a high standard of scholarship. Our writers dedicate their skills and effort to ensure every aspect of your paper, from clarity of language to depth of analysis and precision of information, reflects top-quality work.
• Customized Solutions: Recognizing that each research paper brings a distinct set of challenges and requirements, we offer customized solutions. Our approach is to thoroughly understand your specific needs and shape our writing services accordingly. We ensure that every aspect of your paper, from its overarching structure to the smallest details, aligns with your expectations.
• Flexible Pricing: We believe that high-quality academic writing services should be accessible. That’s why we offer our top-quality services at competitive prices, striking a careful balance between affordability and excellence. We provide a range of pricing options designed to cater to various budget needs without compromising on the quality of our services.
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• Timely Delivery: At iResearchNet, we understand the critical importance of adhering to deadlines in the academic world. We commit to the timely delivery of all orders, ensuring that you are always able to submit your work on time. With our service, you can put aside worries about late submissions.
• 24/7 Support: Academic queries or concerns can arise at any time, and we are here to assist you around the clock. We have a dedicated support team ready to answer your questions, address your concerns, or simply provide guidance about your project, at any time of the day or night.
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• Money Back Guarantee: Your satisfaction is our ultimate goal. We strive to meet your expectations, but if for any reason the final work falls short, we offer a money-back guarantee. This policy is a testament to our confidence in the quality of our services and our commitment to your academic success.

At iResearchNet, we strive to be more than just a writing service provider. We aspire to be a trusted academic partner, providing support and expertise to help you navigate the complexities of writing a biomedical research paper. With our combination of expert knowledge, high commitment to quality, and excellent customer service, we are the ideal choice for all your academic writing needs.

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Biomedical Science

• Getting Started
• Books and eBooks
• FInding full-text articles
• Google Scholar
• Clinical Trials
• Open Science: key websites
• Dissertations and final year projects
• Referencing and Academic Integrity
• Academic Writing
• New Biomed Resources
• Useful LibGuides

Please note :

• TU Dublin use the word "dissertation" for work done as part of an undergraduate or taught master's course, and the word  "thesis" for work done for PhD or research masters degrees
• Dissertations and theses completed before 2019 were submitted to DIT, which preceded TU Dublin, and these are listed as Dublin Institute of Technology works .

Final Year Dissertations

Dissertations for a number of science undergraduate and taught postgraduate programs are available to view in pdf  format from 2014 onwards. To view the outline,  layout, citation style and referencing quality of a science eDissertation follow the steps below:

Start at the TU Dublin Library Catalogue

• From the drop-down search menu choose Subject or  Title Search
• Input your program code e.g. TU852. You can use either a current TU Dublin program code or an older DIT code.
• Select the e Dissertations option.
• Click on the blue dissertations link and view or download the pdf as required. 

 Tip: Sort by Reverse Year to view the newer titles.  

Research Theses

Arrow@TUDublin is the institutional repository for the university and is where researchers and staff  make a version of their theses and published articles or book chapters freely available. All material on Arrow is full text. The theses collection for MPhils and PhDs is also available on Arrow.

• Open Access Theses and Dissertations (OATD)  provides online access to graduate theses and dissertations from over 1100 colleges, universities, and research institutions from around the world.
• The  DART-Europe E-Theses Portal provides access to over 1.6 million open access research theses from 572 Universities in 29 European countries.
• The British Library EThOS theses online service  offers a search option to over 500,000 doctoral theses. Download instantly for your research, or order a scanned copy quickly and easily.

A selection of research theses is also available for use in TU Dublin Library.  A listing of hardcopy PhD theses is available here.  Please note that print theses are for use in the library only.

• << Previous: Open Science: key websites
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• Last Updated: Mar 20, 2024 5:41 PM
• URL: https://tudublin.libguides.com/biomedical_science

Enjoy a completely custom, expertly-written dissertation. Choose from hundreds of writers, all of whom are career specialists in your subject.

45 Biomedical Research Topics for You

Although choosing relevant biomedical research topics is often an arduous task for many, it shouldn’t be for you. You no longer have to worry as we have provided you with a list of topics in biomedical science in this write-up.

Biomedical research is a broad aspect of science, and it is still evolving. This aspect of science involves a variety of ways to prevent and treat diseases that lead to illness and death in people.

This article contains 45 biomedical topics. The topics were carefully selected to guide you in choosing the right topics. They can be used for presentations, seminars, or research purposes, as the case may be.

So, suppose you need topics in biomedical ethics for papers or biomedical thesis topics for various purposes. In that case, you absolutely have to keep reading! Are you ready to see our list of biomedical topics? Then, let’s roll.

Biomedical Engineering Research Topics

Biomedical engineering is the branch of engineering that deals with providing solutions to problems in medicine and biology. Biomedical engineering research is an advanced area of research. Are you considering taking up research in this direction?

Research topics in this area cannot just be coined while eating pizza. It takes a lot of hard work to think out something meaningful. However, we have made a list for you! Here is a list of biomedical engineering topics!

• How to apply deep learning in biomedical engineering
• Bionics: the latest discoveries and applications
• The techniques of genetic engineering
• The relevance of medical engineering today
• How environmental engineering has affected the world

Biomedical Ethics Topics

There are ethical issues surrounding healthcare delivery, research, biotechnology, and medicine. Biomedical Ethics is fundamental to successful practice experience and is addressed by various disciplines. If you want to research this area, then you do not have to look for topics. Here’s a list of biomedical ethics for paper that you can choose from:

• The fundamentals of a physician-patient relationship
• How to handle disability issues as a health care sector
• Resource allocation and distribution
• All you need to know about coercion, consent, and or vulnerability
• Ethical treatment of subjects or animals in clinical trials

Relevant Biomedical Topics

Topics in Biomedical science are numerous, but not all are relevant today. Since biomedical science is constantly evolving, newer topics are coming up. If you desire in your topic selection, read on. Here is a list of relevant biomedical topics just for you!

• The replacement of gene therapy by gene editing
• Revolution of vaccine development by synthetic biology
• Introduction of artificial blood – the impact on the health sector
• Ten things know about artificial womb
• Transplanted reproductive organs and transgender birth

Biomedical Science Topics

Biomedical science is the aspect of scientific studies that focuses on applying biology and chemistry to health care. This field of science has a broad range of disciplines. If you intend to do research in this field, look at this list of research topics in biomedical science.

• The role of biomechanics in health care delivery
• Importance of biomaterials and regeneration engineering
• The application of cell and molecular engineering to medicine
• The evolution of medical instrumentation and devices
• Neural engineering- the latest discoveries

Seminar Topics for Biomedical Instrumentation

Biomedical science is constantly making progress, especially in the aspect of biomedical instrumentation. This makes it worthy of a seminar presentation in schools where it is taught. However, choosing a biomedical research topic for a biomedical instrumentation seminar may not come easy. This is why we have collated five brilliant topics for biomedical instrumentation just for you. They include:

• Microelectrode in neuro-transplants
• Hyperbaric chamber for oxygen therapy
• How concentric ring electrodes can be used to manage epilepsy
• How electromagnetic interference makes cochlear implants work
• Neuroprosthetics Management using Brain-computer interfaces (BCI)

Biomedical Engineering Topics for Presentation

One of the interesting aspects of biomedical science in biomedical engineering. It is the backbone that gives the biomedical science structure. Are you interested in making presentations about biomedical engineering topics? Or do you need biomedical engineering topics for paper? Get started here! We have compiled a list of biomedical engineering topics for you. Here they are:

• In-the-ear device to control stuttering: the basis of its operation
• How to implement the magnetic navigated catheterization
• Semiconductor-cell interfaces: the rudiments of its application
• The benefits of tissue engineering of muscle
• The benefits of sensitive artificial skin for prosthetic arms

Hot Topics in Biomedical Research

Biomedical research is fun because it is often relatable. As interesting as it seems, choosing a topic for research doesn’t come easy at all. Yet, there are also a lot of trending events around biomedical topics. To simplify your selection process, we have written out a few of them here.

Here are some hot biomedical research topics below.

• What is immunology, and what is the relevance today?
• Regenerative medicine- definition, importance, and application
• Myths about antibiotic resistance
• Vaccine development for COVID-19
• Infectious diseases now and before

Biomedical Research Topics

Biomedical research is an extensive process. It requires a lot of time, dedication, and resources. Getting a topic shouldn’t be added to that list. There are biomedical thesis topics and research topics in biomedical science for you here:

• Air pollution- sources, impact, and prevention
• Covid-19 vaccination- the effect on life expectancy
• Hyper insomnia- what is responsible?
• Alzheimer’s disease- newer treatment approaches
• Introduction of MRI compatible infusion pump

Biomedical Nanotechnology Topics

Biomedical research topics and areas now include nanotechnology. Nanotechnology has extended its tentacles to medicine and has been used to treat cancer successfully. This makes it a good research area. It is good for seminar presentations. Here are some biomedical nanotechnology topics below.

• The uses of functional particles and nanomaterials
• Nanoparticles based drug delivery system
• The incorporation of nanoporous membranes into biomedical devices
• Nanostructured materials for biological sensing
• Nanocrystals- imaging, transportation, and toxicity features

Seeking professional assistance to write your biomedical research or thesis? Look no further! At our reputable writing service, our experienced writers specialize in providing tailored support for the complexities of biomedical research. When you say, “ do my thesis for me ” we’re here to guide you through formulating research questions, conducting literature reviews, and analyzing data sets. Entrust the writing process to our experts while you focus on exploring the frontiers of biomedical research. Contact us today for a meticulously crafted thesis that enhances your chances of success.

We believe you have been thoroughly equipped with a list of biomedical topics. This way, you wouldn’t have to go through the stress of choosing a topic for research, seminars, or other educational purposes. Now that you have the topics at your fingertips make your choice and enjoy!

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Home » Blog » Dissertation » Topics » Science » Biomedical Science » 80 Biomedical Science Research Topics

80 Biomedical Science Research Topics

FacebookXEmailWhatsAppRedditPinterestLinkedInIf you are a student seeking compelling research topics in Biomedical Science, Let us help you. Biomedical Science is a Scientific exploration that intersects with medical innovation to unlock the human body’s mysteries and improve healthcare outcomes. From dissecting cellular pathways to pioneering medical technologies, Biomedical Science offers vast research opportunities that promise to transform […]

If you are a student seeking compelling research topics in Biomedical Science, Let us help you. Biomedical Science is a Scientific exploration that intersects with medical innovation to unlock the human body’s mysteries and improve healthcare outcomes. From dissecting cellular pathways to pioneering medical technologies, Biomedical Science offers vast research opportunities that promise to transform lives.

This blog post serves as a beacon for students seeking research topics in this dynamic field. Whether you’re passionate about disease mechanisms, cutting-edge diagnostics, regenerative medicine, or medical ethics, the curated list of research topics below will guide you toward impactful and meaningful contributions to Biomedical Science. As you embark on your academic journey, let these topics ignite your curiosity and lead you toward discoveries that shape the future of healthcare.

A List Of Potential Research Topics In Biomedical Science:

• The role of microRNAs in regulating gene expression and disease development.
• Advancements in 3D printing for personalized medical implants and prosthetics.
• Investigating the gut-brain axis and its implications for mental health disorders.
• Targeting epigenetic modifications for cancer therapy and prevention.
• Precision medicine approaches for autoimmune diseases.
• Biomechanics of bone tissue and implications for osteoporosis treatments.
• Novel strategies for enhancing drug delivery across the blood-brain barrier.
• The role of extracellular vesicles in intercellular communication and disease progression.
• Gene-environment interactions in disease susceptibility and prevention.
• Innovative strategies for gene therapy delivery and integration.
• Immune checkpoint blockade in cancer therapy: Current challenges and future directions.
• Exploring the gut-liver axis and its relevance in metabolic diseases.
• The potential of exosome-based therapies for regenerative medicine.
• Computational models for predicting drug interactions and adverse effects.
• Stem cell-derived organoids as disease models and drug screening platforms.
• Insights into the microbiome’s impact on mental health and neurological disorders.
• Biomechanical engineering for developing functional tissue replacements.
• Addressing antibiotic resistance through novel antimicrobial strategies.
• The gut microbiome is a modulator of immune responses and inflammation.
• Analyzing the role of non-coding RNAs in disease progression.
• Artificial intelligence in predicting disease outbreaks and pandemic control.
• Mechanisms of drug resistance in cancer and strategies to overcome it.
• Biomedical implications of CRISPR-based gene drives for disease control.
• Integrating omics data for comprehensive disease understanding.
• Epitranscriptomics: Exploring RNA modifications and their functional implications.
• Personalized cancer immunotherapy based on tumour mutational profiles.
• Emerging biotechnologies for enhancing tissue and organ transplantation.
• Targeting senescence pathways for anti-aging interventions.
• Role of mitochondrial dysfunction in neurodegenerative diseases.
• Engineering functional biomaterials for wound healing and tissue repair.
• Precision medicine in cardiovascular diseases: Genomics, proteomics, and beyond.
• Immunomodulatory strategies for treating autoimmune and inflammatory disorders.
• Metabolic reprogramming in cancer and therapeutic interventions.
• Regenerative potential of mesenchymal stem cells in tissue repair.
• Engineering synthetic biology circuits for therapeutic applications.
• Neurodegenerative diseases and the potential of gene therapy approaches.
• Harnessing the microbiome for developing novel probiotics and therapeutics.
• Targeting tumour microenvironment for enhancing cancer therapy efficacy.
• Exploring the role of circular RNAs in disease pathogenesis.
• Integrating artificial intelligence with medical imaging for enhanced diagnostics.
• Predictive modelling in personalized medicine for disease treatment optimization.
• Emerging therapies for neurodegenerative disorders like Alzheimer’s and Parkinson’s diseases.
• Nanoparticles as drug delivery agents: Enhancing precision and efficacy.
• Harnessing stem cells and biomaterials for tissue engineering and regenerative medicine.
• Immunotherapies for cancer treatment: Current status and future directions.
• Genomics-driven approaches to precision oncology and targeted therapies.
• Gut microbiome composition and its impact on health and disease.
• Artificial intelligence applications in medical imaging for accurate diagnosis.
• Ethical considerations of CRISPR-Cas9 gene editing for human enhancement.
• Integrating bioinformatics in analyzing complex biological data.
• Cardiovascular applications of stem cell therapy for tissue regeneration.
• Biomarker discovery in personalized medicine: Challenges and innovations.
• Repurposing existing drugs for treating rare and neglected diseases.
• Advancements in vaccine development and distribution strategies.
• Wearable health technology: Transforming patient monitoring and well-being.
• Neuroimaging techniques for studying brain connectivity and disorders.
• Epigenetic modifications and their role in disease progression.
• Lifestyle interventions for managing metabolic syndrome and related disorders.
• Addressing antimicrobial resistance through novel therapeutic approaches.
• Innovations in biomaterials for medical implant design and function.
• Environmental exposures and their impact on disease susceptibility.
• Molecular insights into ageing and strategies for promoting healthy ageing.
• Telemedicine’s potential in remote patient monitoring and healthcare delivery.
• Drug development lifecycle: From discovery to clinical trials.
• Ethical considerations in human and animal biomedical research.
• Neuroplasticity’s role in post-injury brain rehabilitation.
• Metabolomics in disease profiling and diagnostics.
• Harnessing the immune system in cancer therapy with checkpoint inhibitors.
• Molecular diagnostics for rapid and accurate infectious disease diagnosis.
• Personalized nutrition interventions for improved health outcomes.
• Biopharmaceutical production advancements and challenges.
• Genetic basis and potential treatments for rare genetic diseases.
• Ethical implications of human-animal hybrid research in biomedicine.
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In Biomedical Science, these research topics offer boundless possibilities for advancing human health. These avenues pave the way for impactful contributions to medical knowledge and care innovation from undergraduates to doctoral candidates. Your journey in Biomedical Science can shape the future of health and well-being.

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Ph.D. and M.S. in Biomedical Sciences (Research Based)

Our thesis and dissertation-based M.S. and Ph.D. programs are focused on providing individualized, competency-based education to equip our graduates with the skills, abilities, and attitudes to pursue diverse careers related to biomedical sciences.

During the first year, our students acquire a background in biomedical science, consisting of topics in biochemistry, molecular biology, cell biology, pharmacology, physiology and immunology. They also complete lab rotations to identify the mentor and lab for their thesis or dissertation work. Students also complete discipline-specific advanced courses and electives based on their needs and academic discipline.

While working on their thesis or dissertation research, students participate in mentored experimental research projects with faculty who match their interests.

Biomedical Science Disciplines

• Biochemistry and Cancer Biology
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• Integrative Physiology
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• Structural Anatomy and Rehabilitation Science
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Stipend and benefits for PhD students

All students in our PhD in Biomedical Sciences program receive a benefits package that includes a stipend of $30,000 per year plus full tuition, fees, and health insurance. Students also have opportunities to apply for training grants, fellowships, and scholarships.

This page was last modified on February 12, 2024

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Edinburgh Medical School thesis and dissertation collection

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Edinburgh Medical School is one of two schools at the College of Medicine and Veterinary Medicine at the University of Edinburgh. The Edinburgh Medical School integrates research and teaching across our three Deaneries: Biomedical Sciences, Clinical Sciences and Molecular,Genetic and Population Health Sciences.

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Investigating the role of microglial senescence in central nervous system injury and regeneration , characterisation of the pro-regenerative extracellular matrix in the zebrafish spinal cord , different mutations in the beta-tubulin tubb4b result in a novel spectrum of dominant-negative ciliopathies , investigating the modulators of positional identity in human neuromesodermal progenitor differentiation in vitro , role of the succinate receptor in brown adipose tissue function , phenotype of newly generated neurons following spinal cord injury in zebrafish , exploration of relationships between life course measures of socioeconomic status and structural brain changes linked with older life cognitive decline , high resolution analysis of the tumour microenvironment of high grade serous ovarian cancer (hgsoc) using single cell transcriptomics and quantitative histopathological examination , complications of portal hypertension: clinical studies , imaging of abdominal aortic aneurysm disease activity and implications for endovascular aneurysm repair , hallmarks of cotranslational protein complex assembly and its relationship with the dominant-negative effect , optimising islet transplantation therapy for the treatment of type 1 diabetes by targeting the liver niche with etanercept-loaded microparticles to promote the long term function of islets , developing a systematic, data-driven framework to identify, evaluate, and prioritise candidate drugs for clinical trials in motor neuron disease , investigating an arginase 1⁺ monocyte- macrophage population in driving fibrosis in chronic kidney disease. , in vivo investigation of component-specific functions of the hippo pathway , prevalence of female infertility in the uk armed forces , understanding colorectal cancer risk loci that alter transcriptional dynamics , behaviour change intervention for smokeless tobacco (st) cessation delivered by dentists in a dental setting: a feasibility study , dna methylation & its regulation in colorectal tumours , lesion reversibility in small vessel disease: understanding changes contributing to vascular dementia .

Advanced cell atlas opens new doors in biomedical research

Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to increase knowledge about human health and disease. The study is published in Genome Biology.

Simultaneous measurement of numerous biomolecular variables, known as multi-omics, enables deep and comprehensive profiling of human biology. The new Single Cell Atlas (SCA) is based on analyses of thousands of human tissue samples from 125 different adult and fetal tissues. The researchers combined eight cutting-edge omics technologies, including single-cell RNA sequencing, whole-genome sequencing, and spatial transcriptomics to map and localise genes expressed in the tissue.

The platform provides unique insights into individual cell properties and their interactions within tissues. The extensive collection of data is freely accessible through the platform's website.

"The Single Cell Atlas not only saves time and resources but also fosters a collaborative environment for scientists from diverse fields, paving the way for new discoveries and innovations," says the study's first author Lu Pan, researcher at the Institute of Environmental Medicine, Karolinska Institutet, Sweden.

Looking ahead, the team plans to refine the SCA by introducing more detailed analyses and annual updates. These enhancements will fill gaps in tissue representation and expand the sample size, allowing for more precise research.

"The creation of the SCA marks a significant step forward in biomedical research," says the study's last author Xuexin Li, researcher at the Department of Physiology and Pharmacology (previously at the Department of Medical Biochemistry and Biophysics), Karolinska Institutet. "Our goal is to continually enrich the atlas, making it an invaluable resource for understanding human health and disease."

The research was done in collaboration with China Medical University and several other international collaboration partners in The Single Cell Atlas Consortium. The study was financed by Karolinska Institutet and the KI Network Medicine Global Alliance (KI NMA). Coauthor Volker Lauschke is CEO and shareholder of HepaPredict AB, co-founder and shareholder of PersoMedix AB, and discloses consultancy work for Enginzyme AB. The other authors declare that they have no competing interests.

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Materials provided by Karolinska Institutet . Note: Content may be edited for style and length.

Journal Reference :

• Lu Pan, Paolo Parini, Roman Tremmel, Joseph Loscalzo, Volker M. Lauschke, Bradley A. Maron, Paola Paci, Ingemar Ernberg, Nguan Soon Tan, Zehuan Liao, Weiyao Yin, Sundararaman Rengarajan, Xuexin Li. Single Cell Atlas: a single-cell multi-omics human cell encyclopedia . Genome Biology , 2024; 25 (1) DOI: 10.1186/s13059-024-03246-2

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