About Series GRM
Series GRM Clamps are designed specifically for handling sheet metal in stamping/fabricating press applications. A compact size makes the Series GRM Clamp ideal for applications in confined work areas.
Example Series GRM Clamp:
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A Clinical Study of the Pharmacokinetics and Safety of BCD-263 and Opdivo® as Monotherapy in Subjects With Advanced Melanoma of the Skin
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Following screening, subjects will be randomized to receive either BCD-263 or Opdivo in a 1:1 ratio and enter the main study period.
During the main study period, subjects will receive therapy with BCD-263 or Opdivo, which will be administered intravenously until disease progression or signs of unacceptable toxicity develop (whichever occurs earlier).
At Week 25, after completion of all scheduled procedures subjects in both groups will continue to receive open-label BCD-263 for up to a total of 2 years of therapy, or disease progression, or signs of unacceptable toxicity (whichever occurs first).
Following discontinuation of the study therapy, the subjects will enter a follow-up period, during which data on overall survival will be collected through telephone contacts.
Inclusion Criteria:
- Age ≥18 years at the time of signing the informed consent form;
- Body weight 60 to 90 kg.
Histologically confirmed melanoma with the following prognostic characteristics:
- LDH <ULN of local laboratory (enrollment of subjects with LDH <2x ULN of local laboratory is allowed until the number of subjects with LDH >ULN is 30% of the total population of randomized subjects. The Sponsor will inform when enrollment of subjects is limited by LDH level <ULN of the local laboratory).
- Absence, according to the Investigator, of clinically significant symptoms associated with the tumor.
- Absence, according to the Investigator, of rapidly progressing metastatic melanoma.
- Newly diagnosed advanced unresectable (stage III) or metastatic disease (stage IV), or progressive disease during / relapsing after radical treatment.
Exclusion Criteria:
- Indications for radical treatment (surgery, radiation therapy).
- Uveal or mucosal melanoma.
- Previous systemic anticancer therapy for advanced unresectable or metastatic skin melanoma (a history of neoadjuvant or adjuvant therapy is allowed, provided that the therapy was completed at least 12 weeks before randomization).
- Active CNS metastases and/or carcinomatous meningitis.
- Previous invasive cancer, excluding diseases treated with potentially curative therapy with no evidence of recurrence for 2 years from the start of this therapy (subjects with radically resected basal cell carcinoma of the skin, superficial bladder cancer, squamous cell carcinoma of the skin, cervical carcinoma in situ of the uterus and other carcinomas in situ may be included).
- Subjects with severe concomitant disorders, life-threatening acute complications of the primary disease (including massive pleural, pericardial, or peritoneal effusions requiring intervention, pulmonary lymphangitis, bleeding or organ perforation) at the time of signing the informed consent and during the screening period.
- Concomitant diseases and/or conditions that significantly increase the risk of adverse events (AEs) during the study.
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PHD Manufacturing is "The Preferred Source" manufacturer of hangers, bracing, and more for the Fire Sprinkler Industry
Phd manufacturing expert: 1-800-321-2736.
I.P. Pipe Clamps
Figure: 2001 - 2016
Material: Low Carbon Steel, Available In Aluminum And Stainless Steel
Finish: Electro-Galvanized
ORDERING: Specify figure number.
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Overview. Series PFC Pneumatic Frame Clamps feature a rugged cam design that provides consistent clamping force of up to 11,250 pounds throughout a wide power window. A wide jaw throat accommodates large parts with simple tooling. Series PFC Clamps are designed to clamp heavy parts such as the frame of an automobile.
PHD, Inc. Request a Quote. Series PFC Pneumatic Frame Clamps feature a rugged cam design that provides consistent clamping force of up to 11,250 pounds throughout a wide power window. A wide jaw throat accommodates large parts with simple tooling. Series PFC Clamps are designed to clamp heavy parts such as the frame of an automobile.
The forming clamps press the bottom frame section onto the top frame section until the seams overlap and provide an even seam for welding. APPLICATION ... PHD, Inc. 9009 Clubridge Drive P.O. Box 9070, Fort Wayne, Indiana 46899 U.S.A. Phone (260) 747-6151 • Fax (260) 747-6754
Series GRM Pneumatic Workholding Clamps are ideal for sheet metal clamping and feature a simple design, high clamp force, and durability. Units are available in two sizes with 13 jaw styles each, up to 500 pounds clamp force, and include many options for mounting, switches, and tips. The adjustable rotation stop allows for multiple jaw openings ...
FRAME CLAMPS TOGGLE CLAMPS IDENTIFICATION & CRIMPING CLAMPS DIE LIFTERS CLAMPIB18 phdinc.com (800) 624-8511 ... Rugged Design PHD Clamps are rugged, long life actuators. Customer-driven, lab and field-tested designs ensure peak performance throughout the life of the product. You can be assured PHD
PHD designs and manufacturers pneumatic, hydrauli,c and electrical grippers & actuators for Industrial Automation. 1-800-624-8511 ... Series GRM Clamps are designed specifically for handling sheet metal in stamping/fabricating press applications. A compact size makes the Series GRM Clamp ideal for applications in confined work areas. Example ...
Custom Frame Clamp to Interface with Existing Tooling and Meet Performance Requirements. PHD's Custom Solutions engineers collaborated with the automotive company to fully understand the design and performance requirements of the application. It was determined that PHD's standard PFC Clamp's proven technology would meet the customer's force and ...
PHD Manufacturing is "The Preferred Source" manufacturer of hangers, bracing, and more for the Fire Sprinkler Industry PHD Manufacturing Expert: 1-800-321-2736. ... Import Wide Mouth Beam Clamp. Domestic Wide Mouth Beam Clamp. PHD STOCK LOCATIONS PHD ELECTRICAL STOCK LOCATIONS
PHD Manufacturing Expert: 1-800-321-2736. Send a Drawing Request a Quote. Home; About PHD; Products; Literature; Affiliations; What's New; Technical Data; ... Heavy Duty Double Bolt Pipe Clamp. Riser Clamps. Copper Tubing Riser Clamps. Two Bolt Underground Pipe Clamp. Washer For Fig. 580. Four Bolt Underground Pipe Clamp. Washer For Fig. 590 ...
Manhole Frames; Geosynthetics & Stormwater Management; Irrigation & Drainage; Safety & Security; ... PHD Manufacturing Beam Clamps 10 Products Close. Close. Clear All Availability In Store Farmville, 2799 W 3Rd Street ... 3/8 in. Malleable Iron Center Load Beam Clamp with Extension Pipe in Black. 4.3 out of 5 Customer Rating. Info Requires ...
Find many great new & used options and get the best deals for PHD PFC ML314854, FRAME CLAMP #310922 at the best online prices at eBay! Free shipping for many products!
PHD Manufacturing Expert: 1-800-321-2736. Send a Drawing Request a Quote. Home; About PHD; Products; Literature; Affiliations; What's New; Technical Data; ... 7 Series Klo-Shure Clamp For Elastomeric Insulation. 8 Series Klo-Shure Clamp For Elastomeric Insulation. 9 Series Klo-Shure Clamp For Fiberglass Insulation. PHD STOCK LOCATIONS
Function. Material: Finish: CLAMP MATERIAL: Low Carbon Steel, Available In Stainless Steel. CUSHION MATERIAL: Multi-Flex TES A9110 EV1 Black, in accordance with ASTM D4474 TES 0130 A90000. FINISH: Western Gold. ORDERING: Specify figure number. View Data Sheet.
PHD Manufacturing is "The Preferred Source" manufacturer of hangers, bracing, and more for the Fire Sprinkler Industry PHD Manufacturing Expert: 1-800-321-2736. Send a Drawing Request a Quote. ... Beam Clamps. Figure: 7005 - 7007. Function. Material: Malleable Iron. Finish: Electro-Galvanized.
Overview. Series PEC Pneumatic Power Clamps feature a superior cam/roller drive system as compared to toggle mechanisms used by competitors. This provides for the widest range in clamping force in its class and the ability to lock in closed position for the last 6° of rotation. Additionally, multiple output shaft options allow the clamp arms ...
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Efficacy assessment: time to response [ Time Frame: week 25 ] To compare time to response according to RECIST 1.1 and iRECIST criteria after administration of BCD-263 or Opdivo. ... Contact: Anton Lutckii, MD PhD +7 (812) 380 49 33 ext 6768: [email protected]: Locations. Show 30 study locations ...
On 22 March 2024, a terrorist attack which was carried out by the Islamic State (IS) occurred at the Crocus City Hall music venue in Krasnogorsk, Moscow Oblast, Russia.. The attack began at around 20:00 MSK (), shortly before the Russian band Picnic was scheduled to play a sold-out show at the venue. Four gunmen carried out a mass shooting, as well as slashing attacks on the people gathered at ...
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PHD Manufacturing is "The Preferred Source" manufacturer of hangers, bracing, and more for the Fire Sprinkler Industry PHD Manufacturing Expert: 1-800-321-2736. ... I.P. Pipe Clamps. Figure: 2001 - 2016. Function. Material: Low Carbon Steel, Available In Aluminum And Stainless Steel.